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Lee Roberts
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Targeted metabolomics
LD Roberts, AL Souza, RE Gerszten, CB Clish
Current protocols in molecular biology 98 (1), 30.2. 1-30.2. 24, 2012
5342012
Metabolite profiling identifies pathways associated with metabolic risk in humans
S Cheng, EP Rhee, MG Larson, GD Lewis, EL McCabe, D Shen, ...
Circulation 125 (18), 2222-2231, 2012
5272012
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors
LD Roberts, P Boström, JF O’Sullivan, RT Schinzel, GD Lewis, A Dejam, ...
Cell metabolism 19 (1), 96-108, 2014
4602014
Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome
LD Roberts, A Koulman, JL Griffin
The lancet Diabetes & endocrinology 2 (1), 65-75, 2014
2122014
A matter of fat: an introduction to lipidomic profiling methods
LD Roberts, G McCombie, CM Titman, JL Griffin
Journal of Chromatography B 871 (2), 174-181, 2008
1472008
Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway
LD Roberts, T Ashmore, AO Kotwica, SA Murfitt, BO Fernandez, ...
Diabetes 64 (2), 471-484, 2015
1162015
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
LD Roberts, AJ Murray, D Menassa, T Ashmore, AW Nicholls, JL Griffin
Genome biology 12 (8), 1-19, 2011
1052011
Metabolic phenotyping of a model of adipocyte differentiation
LD Roberts, S Virtue, A Vidal-Puig, AW Nicholls, JL Griffin
Physiological genomics 39 (2), 109-119, 2009
972009
Toward new biomarkers of cardiometabolic diseases
LD Roberts, RE Gerszten
Cell metabolism 18 (1), 43-50, 2013
772013
Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
FWB Sanders, A Acharjee, C Walker, L Marney, LD Roberts, F Imamura, ...
Genome biology 19 (1), 1-15, 2018
742018
Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance
C Yew Tan, S Virtue, S Murfitt, LD Roberts, YH Phua, M Dale, JL Griffin, ...
Scientific reports 5 (1), 1-11, 2015
712015
Dietary inorganic nitrate: From villain to hero in metabolic disease?
B McNally, JL Griffin, LD Roberts
Molecular nutrition & food research 60 (1), 67-78, 2016
642016
PTPMT1 inhibition lowers glucose through succinate dehydrogenase phosphorylation
AK Nath, JH Ryu, YN Jin, LD Roberts, A Dejam, RE Gerszten, ...
Cell reports 10 (5), 694-701, 2015
562015
Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism
T Ashmore, LD Roberts, AJ Morash, AO Kotwica, J Finnerty, JA West, ...
BMC biology 13 (1), 1-17, 2015
552015
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice
ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ...
Science translational medicine 10 (454), eaar2718, 2018
522018
Inorganic nitrate mimics exercise-stimulated muscular fiber-type switching and myokine and γ-aminobutyric acid release
LD Roberts, T Ashmore, BD McNally, SA Murfitt, BO Fernandez, ...
Diabetes 66 (3), 674-688, 2017
462017
Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure
AK Nath, LD Roberts, Y Liu, SB Mahon, S Kim, JH Ryu, A Werdich, ...
The FASEB Journal 27 (5), 1928-1938, 2013
452013
A role for vaccinia virus protein C16 in reprogramming cellular energy metabolism
M Mazzon, C Castro, LD Roberts, JL Griffin, GL Smith
The Journal of general virology 96 (Pt 2), 395, 2015
392015
Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor δ from Peroxisome proliferator-activated receptor γ in the ob/obmouse
LD Roberts, DG Hassall, DA Winegar, JN Haselden, AW Nicholls, ...
Genome Medicine 1 (12), 1-12, 2009
382009
Metabolomics and lipidomics study of mouse models of type 1 diabetes highlights divergent metabolism in purine and tryptophan metabolism prior to disease onset
SA Murfitt, P Zaccone, X Wang, A Acharjee, Y Sawyer, A Koulman, ...
Journal of proteome research 17 (3), 946-960, 2018
312018
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