Henrike O. Heyne
Henrike O. Heyne
Hasso Plattner Institute Potsdam, FIMM, University of Helsinki, Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
STXBP1 encephalopathy: a neurodevelopmental disorder including epilepsy
H Stamberger, M Nikanorova, MH Willemsen, P Accorsi, M Angriman, ...
Neurology 86 (10), 954-962, 2016
1832016
De novo variants in neurodevelopmental disorders with epilepsy
HO Heyne, T Singh, H Stamberger, R Abou Jamra, H Caglayan, D Craiu, ...
Nature genetics 50 (7), 1048-1053, 2018
1462018
GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects
K Platzer, H Yuan, H Schütz, A Winschel, W Chen, C Hu, H Kusumoto, ...
Journal of medical genetics 54 (7), 460-470, 2017
1272017
Delineating the GRIN1 phenotypic spectrum: a distinct genetic NMDA receptor encephalopathy
JR Lemke, K Geider, KL Helbig, HO Heyne, H Schütz, J Hentschel, ...
Neurology 86 (23), 2171-2178, 2016
1112016
Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals
YCA Feng, DP Howrigan, LE Abbott, K Tashman, F Cerrato, T Singh, ...
The American Journal of Human Genetics 105 (2), 267-282, 2019
962019
GRIN2A-related disorders: genotype and functional consequence predict phenotype
V Strehlow, HO Heyne, DRM Vlaskamp, KFM Marwick, G Rudolf, ...
Brain 142 (1), 80-92, 2019
672019
Neolithic and medieval virus genomes reveal complex evolution of hepatitis B
B Krause-Kyora, J Susat, FM Key, D Kühnert, E Bosse, A Immel, C Rinne, ...
Elife 7, e36666, 2018
652018
Genetic influences on brain gene expression in rats selected for tameness and aggression
HO Heyne, S Lautenschläger, R Nelson, F Besnier, M Rotival, A Cagan, ...
Genetics 198 (3), 1277-1290, 2014
602014
Widely used commercial ELISA does not detect precursor of haptoglobin2, but recognizes properdin as a potential second member of the zonulin family
L Scheffler, A Crane, H Heyne, A Tönjes, D Schleinitz, CH Ihling, ...
Frontiers in endocrinology 9, 22, 2018
522018
Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes
L Massier, R Chakaroun, S Tabei, A Crane, KD Didt, J Fallmann, ...
Gut 69 (10), 1796-1806, 2020
402020
Delineating SPTAN1 associated phenotypes: from isolated epilepsy to encephalopathy with progressive brain atrophy
S Syrbe, FL Harms, E Parrini, M Montomoli, U Mütze, KL Helbig, T Polster, ...
Brain 140 (9), 2322-2336, 2017
402017
Paternal-age-related de novo mutations and risk for five disorders
JL Taylor, JCPG Debost, SU Morton, EM Wigdor, HO Heyne, D Lal, ...
Nature communications 10 (1), 1-9, 2019
302019
Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia
T Singh, T Poterba, D Curtis, H Akil, M Al Eissa, JD Barchas, N Bass, ...
MedRxiv, 2020
272020
Targeted gene sequencing in 6994 individuals with neurodevelopmental disorder with epilepsy
HO Heyne, M Artomov, F Battke, C Bianchini, DR Smith, N Liebmann, ...
Genetics in Medicine 21 (11), 2496-2503, 2019
232019
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels
HO Heyne, D Baez-Nieto, S Iqbal, DS Palmer, A Brunklaus, P May, ...
Science translational medicine 12 (556), 2020
222020
Biological concepts in human sodium channel epilepsies and their relevance in clinical practice
A Brunklaus, J Du, F Steckler, II Ghanty, KM Johannesen, CD Fenger, ...
Epilepsia 61 (3), 387-399, 2020
202020
Identification of pathogenic variant enriched regions across genes and gene families
E Pérez-Palma, P May, S Iqbal, LM Niestroj, J Du, HO Heyne, ...
Genome research 30 (1), 62-71, 2020
152020
Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants
S Iqbal, E Pérez-Palma, JB Jespersen, P May, D Hoksza, HO Heyne, ...
Proceedings of the National Academy of Sciences 117 (45), 28201-28211, 2020
92020
Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin
A Tönjes, M Scholz, J Krüger, K Krause, D Schleinitz, H Kirsten, ...
Human molecular genetics 27 (3), 546-558, 2018
72018
Widely used commercial ELISA for human Zonulin reacts with Complement C3 rather than preHaptoglobin2
L Scheffler, A Crane, H Heyne, A Tönjes, D Schleinitz, CH Ihling, ...
bioRxiv, 157578, 2017
72017
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Articles 1–20