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Jesse D. Bloom
Jesse D. Bloom
Fred Hutch Cancer Center; University of Washington; Howard Hughes Medical Institute
Bestätigte E-Mail-Adresse bei fredhutch.org - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
cell 182 (5), 1295-1310. e20, 2020
19612020
Protein stability promotes evolvability
JD Bloom, ST Labthavikul, CR Otey, FH Arnold
Proceedings of the National Academy of Sciences 103 (15), 5869-5874, 2006
13422006
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ...
Cell host & microbe 29 (3), 463-476. e6, 2021
12522021
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
11062021
Why highly expressed proteins evolve slowly
DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005
9062005
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ...
Science 371 (6531), 850-854, 2021
7672021
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays
KHD Crawford, R Eguia, AS Dingens, AN Loes, KD Malone, CR Wolf, ...
Viruses 12 (5), 513, 2020
7612020
Permissive secondary mutations enable the evolution of influenza oseltamivir resistance
JD Bloom, LI Gong, D Baltimore
Science 328 (5983), 1272-1275, 2010
7592010
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate
A Addetia, KHD Crawford, A Dingens, H Zhu, P Roychoudhury, ML Huang, ...
Journal of clinical microbiology 58 (11), 10.1128/jcm. 02107-20, 2020
6162020
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020
EB Hodcroft, M Zuber, S Nadeau, TG Vaughan, KHD Crawford, ...
Nature 595 (7869), 707-712, 2021
6002021
In the light of directed evolution: pathways of adaptive protein evolution
JD Bloom, FH Arnold
Proceedings of the National Academy of Sciences 106 (supplement_1), 9995-10000, 2009
5712009
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
TN Starr, AJ Greaney, AS Dingens, JD Bloom
Cell Reports Medicine 2 (4), 2021
4892021
Evolving strategies for enzyme engineering
JD Bloom, MM Meyer, P Meinhold, CR Otey, D MacMillan, FH Arnold
Current opinion in structural biology 15 (4), 447-452, 2005
4792005
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
4422021
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
AJ Greaney, TN Starr, CO Barnes, Y Weisblum, F Schmidt, M Caskey, ...
Nature communications 12 (1), 4196, 2021
407*2021
Thermodynamic prediction of protein neutrality
JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005
4002005
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
Nature microbiology 6 (10), 1233-1244, 2021
395*2021
Stability-mediated epistasis constrains the evolution of an influenza protein
LI Gong, MA Suchard, JD Bloom
Elife 2, e00631, 2013
3742013
Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection
KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, ...
The Journal of infectious diseases 223 (2), 197-205, 2021
3102021
The interface of protein structure, protein biophysics, and molecular evolution
DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ...
Protein Science 21 (6), 769-785, 2012
2382012
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