Julian Knight
Julian Knight
Professor of Genomic Medicine, University of Oxford
Verified email at well.ox.ac.uk - Homepage
Title
Cited by
Cited by
Year
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10269), 99-111, 2021
21802021
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
15802013
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ...
The Lancet 396 (10249), 467-478, 2020
15122020
A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution
SV Ramagopalan, A Heger, AJ Berlanga, NJ Maugeri, MR Lincoln, ...
Genome research 20 (10), 1352-1360, 2010
9602010
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ...
The Lancet 396 (10267), 1979-1993, 2020
7152020
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 2014
6422014
Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D
SV Ramagopalan, NJ Maugeri, L Handunnetthi, MR Lincoln, SM Orton, ...
PLoS genetics 5 (2), e1000369, 2009
6142009
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
JC Knight, I Udalova, AVS Hill, BM Greenwood, N Peshu, K Marsh, ...
Nature genetics 22 (2), 145-150, 1999
5961999
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Y Peng, AJ Mentzer, G Liu, X Yao, Z Yin, D Dong, W Dejnirattisai, ...
Nature immunology 21 (11), 1336-1345, 2020
5422020
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four …
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10277), 881-891, 2021
5282021
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ...
Nature genetics 44 (5), 502-510, 2012
4942012
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
J Bentham, DL Morris, DSC Graham, CL Pinder, P Tombleson, ...
Nature genetics 47 (12), 1457-1464, 2015
4932015
Major histocompatibility complex genomics and human disease
J Trowsdale, JC Knight
Annual review of genomics and human genetics 14, 301-323, 2013
4922013
Genetic mechanisms of critical illness in Covid-19
E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ...
Nature 591 (7848), 92-98, 2021
4692021
Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera
D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer, HM Ginn, Y Zhao, ...
Cell 184 (9), 2348-2361. e6, 2021
4322021
Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
EE Davenport, KL Burnham, J Radhakrishnan, P Humburg, P Hutton, ...
The Lancet Respiratory Medicine 4 (4), 259-271, 2016
3572016
The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319 , a novel gene involved in neuronal migration
S Paracchini, A Thomas, S Castro, C Lai, M Paramasivam, Y Wang, ...
Human molecular genetics 15 (10), 1659-1666, 2006
3262006
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
3152018
Regulatory polymorphisms underlying complex disease traits
JC Knight
Journal of molecular medicine 83 (2), 97-109, 2005
3042005
Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles
W McGuire, JC Knight, AVS Hill, CEM Allsopp, BM Greenwood, ...
The Journal of infectious diseases 179 (1), 287-290, 1999
3001999
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