| Pharmacology of L-type calcium channels: novel drugs for old targets? J Striessnig, N J. Ortner, A Pinggera Current molecular pharmacology 8 (2), 110-122, 2015 | 139 | 2015 |
| L-type calcium channels as drug targets in CNS disorders NJ Ortner, J Striessnig Channels 10 (1), 7-13, 2016 | 118 | 2016 |
| Lower affinity of isradipine for L-type Ca2+ channels during substantia nigra dopamine neuron-like activity: implications for neuroprotection in Parkinson's disease NJ Ortner, G Bock, A Dougalis, M Kharitonova, J Duda, S Hess, P Tuluc, ... Journal of Neuroscience 37 (28), 6761-6777, 2017 | 97 | 2017 |
| Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators NJ Ortner, G Bock, DHF Vandael, R Mauersberger, HJ Draheim, R Gust, ... Nature Communications 5 (1), 3897, 2014 | 64 | 2014 |
| De novo CACAN1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism NJ Ortner, T Kaserer, JN Copeland, J Striessnig Pflügers Archiv-European Journal of Physiology 472, 755-773, 2020 | 60 | 2020 |
| STAC proteins associate to the IQ domain of CaV1. 2 and inhibit calcium-dependent inactivation M Campiglio, PC de Bagneaux, NJ Ortner, P Tuluc, BE Flucher Biophysical Journal 114 (3), 638a, 2018 | 52 | 2018 |
| Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder NT Hofer, P Tuluc, NJ Ortner, YV Nikonishyna, ML Fernándes-Quintero, ... Molecular autism 11, 1-18, 2020 | 47 | 2020 |
| C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1. 3 L-type Ca2+ channels A Lieb, N Ortner, J Striessnig Biophysical journal 106 (7), 1467-1475, 2014 | 44 | 2014 |
| A polybasic plasma membrane binding motif in the I-II linker stabilizes voltage-gated CaV1. 2 calcium channel function G Kaur, A Pinggera, NJ Ortner, A Lieb, MJ Sinnegger-Brauns, ... Journal of Biological Chemistry 290 (34), 21086-21100, 2015 | 38 | 2015 |
| Voltage-Gated Ca2+ Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease? NJ Ortner Frontiers in synaptic neuroscience 13, 636103, 2021 | 32 | 2021 |
| RBP2 stabilizes slow Cav1.3 Ca2+ channel inactivation properties of cochlear inner hair cells NJ Ortner, A Pinggera, NT Hofer, A Siller, N Brandt, A Raffeiner, K Vilusic, ... Pflügers Archiv-European Journal of Physiology 472, 3-25, 2020 | 23 | 2020 |
| Ca2+ Channel Blockers J Striessnig, NJ Ortner Encyclopedia of Molecular Pharmacology, 375-383, 2022 | 15 | 2022 |
| The human channel gating–modifying A749G CACNA1D (Cav1. 3) variant induces a neurodevelopmental syndrome–like phenotype in mice NJ Ortner, A Sah, E Paradiso, J Shin, S Stojanovic, N Hammer, ... JCI insight 8 (20), 2023 | 14 | 2023 |
| Cav1.3‐selective inhibitors of voltage‐gated L‐type Ca2+ channels: Fact or (still) fiction? L Filippini, NJ Ortner, T Kaserer, J Striessnig British Journal of Pharmacology 180 (10), 1289-1303, 2023 | 13 | 2023 |
| Germline de novo variant F747S extends the phenotypic spectrum of CACNA1D Ca2+ channelopathies F Török, K Tezcan, L Filippini, ML Fernández-Quintero, L Zanetti, KR Liedl, ... Human Molecular Genetics 32 (5), 847-859, 2023 | 12 | 2023 |
| β2-subunit alternative splicing stabilizes Cav2. 3 Ca2+ channel activity during continuous midbrain dopamine neuron-like activity A Siller, NT Hofer, G Tomagra, N Burkert, S Hess, J Benkert, A Gaifullina, ... Elife 11, e67464, 2022 | 12 | 2022 |
| CACNA1D-Related Channelopathies: From Hypertension to Autism NJ Ortner Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in …, 2023 | 8 | 2023 |
| Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1. 1 Y El Ghaleb, NJ Ortner, W Posch, ML Fernández-Quintero, WE Tuinte, ... Biophysical Journal 121 (3), 88a, 2022 | 6 | 2022 |
| Novel protocol for multiple-dose oral administration of the L-type Ca2+ channel blocker isradipine in mice: A dose-finding pharmacokinetic study T Theiner, NJ Ortner, H Oberacher, G Stojanovic, P Tuluc, J Striessnig Channels 18 (1), 2335469, 2024 | 3 | 2024 |
| Novel CACNA1A Variant p.Cys256Phe Disrupts Disulfide Bonds and Causes Spinocerebellar Ataxia YV Nikonishyna, NJ Ortner, T Kaserer, J Hoffmann, S Biskup, M Dafotakis, ... Movement Disorders 37 (2), 401-404, 2022 | 3 | 2022 |
