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Nadine Jasmin Ortner
Nadine Jasmin Ortner
Bestätigte E-Mail-Adresse bei uibk.ac.at
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Zitiert von
Jahr
Pharmacology of L-type calcium channels: novel drugs for old targets?
J Striessnig, N J Ortner, A Pinggera
Current molecular pharmacology 8 (2), 110-122, 2015
1312015
L-type calcium channels as drug targets in CNS disorders
NJ Ortner, J Striessnig
Channels 10 (1), 7-13, 2016
1062016
Lower affinity of isradipine for L-type Ca2+ channels during substantia nigra dopamine neuron-like activity: implications for neuroprotection in Parkinson's disease
NJ Ortner, G Bock, A Dougalis, M Kharitonova, J Duda, S Hess, P Tuluc, ...
Journal of Neuroscience 37 (28), 6761-6777, 2017
842017
Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators
NJ Ortner, G Bock, DHF Vandael, R Mauersberger, HJ Draheim, R Gust, ...
Nature communications 5 (1), 3897, 2014
622014
STAC proteins associate to the IQ domain of CaV1. 2 and inhibit calcium-dependent inactivation
M Campiglio, PC de Bagneaux, NJ Ortner, P Tuluc, BE Flucher
Biophysical Journal 114 (3), 638a, 2018
512018
C-terminal modulatory domain controls coupling of voltage-sensing to pore opening in Cav1. 3 L-type Ca2+ channels
A Lieb, N Ortner, J Striessnig
Biophysical journal 106 (7), 1467-1475, 2014
422014
De novo CACAN1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism
NJ Ortner, T Kaserer, JN Copeland, J Striessnig
Pflügers Archiv-European Journal of Physiology 472, 755-773, 2020
412020
Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder
NT Hofer, P Tuluc, NJ Ortner, YV Nikonishyna, ML Fernándes-Quintero, ...
Molecular autism 11, 1-18, 2020
402020
A polybasic plasma membrane binding motif in the I-II linker stabilizes voltage-gated CaV1. 2 calcium channel function
G Kaur, A Pinggera, NJ Ortner, A Lieb, MJ Sinnegger-Brauns, ...
Journal of Biological Chemistry 290 (34), 21086-21100, 2015
342015
Voltage-Gated Ca2+ Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?
NJ Ortner
Frontiers in synaptic neuroscience 13, 5, 2021
262021
RBP2 stabilizes slow Cav1.3 Ca2+ channel inactivation properties of cochlear inner hair cells
NJ Ortner, A Pinggera, NT Hofer, A Siller, N Brandt, A Raffeiner, K Vilusic, ...
Pflügers Archiv-European Journal of Physiology 472, 3-25, 2020
182020
Ca2+ Channel Blockers
J Striessnig, NJ Ortner
Encyclopedia of Molecular Pharmacology, 375-383, 2022
132022
β2-subunit alternative splicing stabilizes Cav2. 3 Ca2+ channel activity during continuous midbrain dopamine neuron-like activity
A Siller, NT Hofer, G Tomagra, N Burkert, S Hess, J Benkert, A Gaifullina, ...
Elife 11, e67464, 2022
102022
Germline de novo variant F747S extends the phenotypic spectrum of CACNA1D Ca2+ channelopathies
F Török, K Tezcan, L Filippini, ML Fernández-Quintero, L Zanetti, KR Liedl, ...
Human Molecular Genetics 32 (5), 847-859, 2023
62023
Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1. 1
Y El Ghaleb, NJ Ortner, W Posch, ML Fernández-Quintero, WE Tuinte, ...
Biophysical Journal 121 (3), 88a, 2022
62022
Cav1.3‐selective inhibitors of voltage‐gated L‐type Ca2+ channels: Fact or (still) fiction?
L Filippini, NJ Ortner, T Kaserer, J Striessnig
British Journal of Pharmacology 180 (10), 1289-1303, 2023
42023
Novel CACNA1A Variant p.Cys256Phe Disrupts Disulfide Bonds and Causes Spinocerebellar Ataxia
YV Nikonishyna, NJ Ortner, T Kaserer, J Hoffmann, S Biskup, M Dafotakis, ...
Movement Disorders 37 (2), 401-404, 2022
32022
CaV1.3 L-type Ca2+ channel modulates pancreatic β-cell electrical activity and survival: Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and …
T Theiner, N Jacobo-Piqueras, NJ Ortner, SM Geisler, P Tuluc
Journal of General Physiology 154 (9), e2021ecc34, 2021
32021
CACNA1D-Related Channelopathies: From Hypertension to Autism
NJ Ortner
22023
The human channel gating–modifying A749G CACNA1D (Cav1. 3) variant induces a neurodevelopmental syndrome–like phenotype in mice
NJ Ortner, A Sah, E Paradiso, J Shin, S Stojanovic, N Hammer, ...
JCI insight 8 (20), 2023
12023
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