| Selective tumor cell targeting using low-affinity, multivalent interactions CB Carlson, P Mowery, RM Owen, EC Dykhuizen, LL Kiessling ACS chemical biology 2 (2), 119-127, 2007 | 319 | 2007 |
| BAF complexes facilitate decatenation of DNA by topoisomerase IIα EC Dykhuizen, DC Hargreaves, EL Miller, K Cui, A Korshunov, M Kool, ... Nature 497 (7451), 624-627, 2013 | 287 | 2013 |
| Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes A Alpsoy, EC Dykhuizen Journal of Biological Chemistry 293 (11), 3892-3903, 2018 | 206 | 2018 |
| Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth EC Dykhuizen, JF May, A Tongpenyai, LL Kiessling Journal of the American chemical society 130 (21), 6706-6707, 2008 | 123 | 2008 |
| Selection of DNA-encoded libraries to protein targets within and on living cells B Cai, D Kim, S Akhand, Y Sun, RJ Cassell, A Alpsoy, EC Dykhuizen, ... Journal of the American Chemical Society 141 (43), 17057-17061, 2019 | 96 | 2019 |
| PBRM1 regulates the expression of genes involved in metabolism and cell adhesion in renal clear cell carcinoma B Chowdhury, EG Porter, JC Stewart, CR Ferreira, MJ Schipma, ... PloS one 11 (4), e0153718, 2016 | 93 | 2016 |
| A chemoproteomic portrait of the oncometabolite fumarate RA Kulkarni, DW Bak, D Wei, SE Bergholtz, CA Briney, JH Shrimp, ... Nature chemical biology 15 (4), 391-400, 2019 | 82 | 2019 |
| Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and atrocytes that express CRH-R1 SL Stevens, TE Shaw, E Dykhuizen, NS Lessov, JK Hill, W Wurst, ... Journal of Cerebral Blood Flow & Metabolism 23 (10), 1151-1159, 2003 | 67 | 2003 |
| Individual bromodomains of polybromo-1 contribute to chromatin association and tumor suppression in clear cell renal carcinoma EG Porter, EC Dykhuizen Journal of Biological Chemistry 292 (7), 2601-2610, 2017 | 61 | 2017 |
| Optimization of ligands using focused DNA-encoded libraries to develop a selective, cell-permeable CBX8 chromodomain inhibitor S Wang, KE Denton, KF Hobbs, T Weaver, JMB McFarlane, KE Connelly, ... ACS chemical biology 15 (1), 112-131, 2019 | 58 | 2019 |
| Compositional and functional diversity of canonical PRC1 complexes in mammals KE Connelly, EC Dykhuizen Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (2), 233-245, 2017 | 56 | 2017 |
| Robustness of in vitro selection assays of DNA-encoded peptidomimetic ligands to CBX7 and CBX8 KE Denton, S Wang, MC Gignac, N Milosevich, F Hof, EC Dykhuizen, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 23 (5), 417-428, 2018 | 53 | 2018 |
| BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression A Alpsoy, SM Utturkar, BC Carter, A Dhiman, SE Torregrosa-Allen, ... Cancer research 81 (4), 820-833, 2021 | 48 | 2021 |
| Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite EC Dykhuizen, LL Kiessling Organic letters 11 (1), 193-196, 2009 | 46 | 2009 |
| Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association KE Connelly, TM Weaver, A Alpsoy, BX Gu, CA Musselman, ... Nucleic acids research 47 (5), 2289-2305, 2019 | 44 | 2019 |
| Small molecule targeting of specific BAF (mSWI/SNF) complexes for HIV latency reversal CA Marian, M Stoszko, L Wang, MW Leighty, E de Crignis, CA Maschinot, ... Cell chemical biology 25 (12), 1443-1455. e14, 2018 | 43 | 2018 |
| Small molecule inhibitors of BAF; a promising family of compounds in HIV-1 latency reversal M Stoszko, E De Crignis, C Rokx, MM Khalid, C Lungu, RJ Palstra, ... EBioMedicine 3, 108-121, 2016 | 42 | 2016 |
| A novel CRISPR/Cas9-Based cellular model to explore adenylyl cyclase and cAMP signaling M Soto-Velasquez, MP Hayes, A Alpsoy, EC Dykhuizen, VJ Watts Molecular pharmacology 94 (3), 963-972, 2018 | 32 | 2018 |
| Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation EC Dykhuizen, LC Carmody, N Tolliday, GR Crabtree, MAJ Palmer Journal of biomolecular screening 17 (9), 1221-1230, 2012 | 31 | 2012 |
| Analysis of human nuclear protein complexes by quantitative mass spectrometry profiling KE Connelly, V Hedrick, TJ Paschoal Sobreira, EC Dykhuizen, UK Aryal Proteomics 18 (11), 1700427, 2018 | 30 | 2018 |
