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Alistair J. Henry
Alistair J. Henry
Sonstige NamenAlistair Henry
UCB
Bestätigte E-Mail-Adresse bei ucb.com
Titel
Zitiert von
Zitiert von
Jahr
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
MS Ominsky, F Vlasseros, J Jolette, SY Smith, B Stouch, G Doellgast, ...
Journal of Bone and Mineral Research 25 (5), 948-959, 2010
5392010
Structure and interactions of the human programmed cell death 1 receptor
X Cheng, V Veverka, A Radhakrishnan, LC Waters, FW Muskett, ...
Journal of Biological Chemistry 288 (17), 11771-11785, 2013
3522013
Characterization of the structural features and interactions of sclerostin
V Veverka, AJ Henry, PM Slocombe, A Ventom, B Mulloy, FW Muskett, ...
Journal of Biological Chemistry 284 (16), 10890-10900, 2009
2872009
The crystal structure of IgE Fc reveals an asymmetrically bent conformation
T Wan, RL Beavil, SM Fabiane, AJ Beavil, MK Sohi, M Keown, RJ Young, ...
Nature immunology 3 (7), 681-686, 2002
2132002
Sclerostin-binding antibody
C Paszty, MK Robinson, K Graham, AJ Henry, KS Hoffmann, J Latham, ...
US Patent 7,592,429, 2009
1592009
Participation of the N-terminal region of Cε3 in the binding of human IgE to its high-affinity receptor FcεRI
AJ Henry, JPD Cook, JM McDonnell, GA Mackay, J Shi, BJ Sutton, ...
Biochemistry 36 (50), 15568-15578, 1997
1421997
The structure of the IgE Cɛ2 domain and its role in stabilizing the complex with its high-affinity receptor FcɛRIα
JM McDonnell, R Calvert, RL Beavil, AJ Beavil, AJ Henry, BJ Sutton, ...
Nature structural biology 8 (5), 437-441, 2001
1182001
Dynamics of intact immunoglobulin G explored by drift‐tube ion‐mobility mass spectrometry and molecular modeling
KJ Pacholarz, M Porrini, RA Garlish, RJ Burnley, RJ Taylor, AJ Henry, ...
Angewandte Chemie International Edition 53 (30), 7765-7769, 2014
1122014
Upregulation of FcϵRI on human basophils by IgE antibody is mediated by interaction of IgE with FcϵRI
D MacGlashan Jr, LM Lichtenstein, J McKenzie-White, K Chichester, ...
Journal of allergy and clinical immunology 104 (2), 492-498, 1999
1061999
Epitopes
M Robinson, A Henry, A Lawson, H Lu, C Paszty, K Hoffmann, J Latham, ...
US Patent App. 11/410,540, 2007
1042007
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI
B Dhaliwal, D Yuan, MOY Pang, AJ Henry, K Cain, A Oxbrow, ...
Proceedings of the National Academy of Sciences 109 (31), 12686-12691, 2012
1002012
A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control
RD Evans, VC Perkins, A Henry, PE Stephens, MK Robinson, FM Watt
The Journal of cell biology 160 (4), 589-596, 2003
982003
Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling
S Shaw, T Bourne, C Meier, B Carrington, R Gelinas, A Henry, ...
MAbs 6 (3), 773-781, 2014
962014
Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors
G Holdsworth, P Slocombe, C Doyle, B Sweeney, V Veverka, K Le Riche, ...
Journal of Biological Chemistry 287 (32), 26464-26477, 2012
942012
Identification of contact residues in the IgE binding site of human FcεRIα
JPD Cook, AJ Henry, JM McDonnell, RJ Owens, BJ Sutton, HJ Gould
Biochemistry 36 (50), 15579-15588, 1997
911997
Automated protein–ligand interaction screening by mass spectrometry
HJ Maple, RA Garlish, L Rigau-Roca, J Porter, I Whitcombe, CE Prosser, ...
Journal of Medicinal Chemistry 55 (2), 837-851, 2012
812012
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
AM Davies, EG Allan, AH Keeble, J Delgado, BP Cossins, AN Mitropoulou, ...
Journal of Biological Chemistry 292 (24), 9975-9987, 2017
732017
Engineering an improved IgG4 molecule with reduced disulfide bond heterogeneity and increased Fab domain thermal stability
SJ Peters, CM Smales, AJ Henry, PE Stephens, S West, DP Humphreys
Journal of Biological Chemistry 287 (29), 24525-24533, 2012
722012
Alternative antibody Fab′ fragment PEGylation strategies: combination of strong reducing agents, disruption of the interchain disulphide bond and disulphide engineering
DP Humphreys, SP Heywood, A Henry, L Ait-Lhadj, P Antoniw, ...
Protein Engineering, Design & Selection 20 (5), 227-234, 2007
692007
Secretion of recombinant human IgE-Fc by mammalian cells and biological activity of glycosylation site mutants
RJ Young, RJ Owens, GA Mackay, CMW Chan, J Shi, M Hide, DM Francis, ...
Protein Engineering, Design and Selection 8 (2), 193-199, 1995
691995
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