| Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation M Muik, I Frischauf, I Derler, M Fahrner, J Bergsmann, P Eder, R Schindl, ... Journal of Biological Chemistry 283 (12), 8014-8022, 2008 | 497 | 2008 |
| A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels M Muik, M Fahrner, I Derler, R Schindl, J Bergsmann, I Frischauf, ... Journal of biological chemistry 284 (13), 8421-8426, 2009 | 399 | 2009 |
| STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation M Muik, M Fahrner, R Schindl, P Stathopulos, I Frischauf, I Derler, P Plenk, ... The EMBO journal 30 (9), 1678-1689, 2011 | 278 | 2011 |
| TRPC3 and TRPC4 associate to form a redox-sensitive cation channel: evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells M Poteser, A Graziani, C Rosker, P Eder, I Derler, H Kahr, MX Zhu, ... Journal of Biological Chemistry 281 (19), 13588-13595, 2006 | 245 | 2006 |
| Novel pyrazole compounds for pharmacological discrimination between receptor‐operated and store‐operated Ca2+ entry pathways H Schleifer, B Doleschal, M Lichtenegger, R Oppenrieder, I Derler, ... British journal of pharmacology 167 (8), 1712-1722, 2012 | 198 | 2012 |
| Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1–3 channels by a STIM1 coiled-coil mutant I Frischauf, M Muik, I Derler, J Bergsmann, M Fahrner, R Schindl, ... Journal of biological chemistry 284 (32), 21696-21706, 2009 | 196 | 2009 |
| 2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size R Schindl, J Bergsmann, I Frischauf, I Derler, M Fahrner, M Muik, R Fritsch, ... Journal of Biological Chemistry 283 (29), 20261-20267, 2008 | 167 | 2008 |
| Molecular mechanisms of STIM/Orai communication I Derler, I Jardin, C Romanin American Journal of Physiology-Cell Physiology 310 (8), C643-C662, 2016 | 165 | 2016 |
| A Ca2+ Release-activated Ca2+ (CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca2+-dependent Inactivation of ORAI1 Channels*♦ I Derler, M Fahrner, M Muik, B Lackner, R Schindl, K Groschner, ... Journal of biological chemistry 284 (37), 24933-24938, 2009 | 160 | 2009 |
| The action of selective CRAC channel blockers is affected by the Orai pore geometry I Derler, R Schindl, R Fritsch, P Heftberger, MC Riedl, M Begg, D House, ... Cell calcium 53 (2), 139-151, 2013 | 157 | 2013 |
| The Extended Transmembrane Orai1 N-Terminal (ETON) Region Combines Binding Interface and Gate for Orai1 Activation by STIM1*♦ I Derler, P Plenk, M Fahrner, M Muik, I Jardin, R Schindl, HJ Gruber, ... Journal of Biological Chemistry 288 (40), 29025-29034, 2013 | 151 | 2013 |
| The STIM/Orai coupling machinery I Frischauf, R Schindl, I Derler, J Bergsmann, M Fahrner, C Romanin Channels 2 (4), 261-268, 2008 | 146 | 2008 |
| Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+‐dependent inactivation I Derler, M Hofbauer, H Kahr, R Fritsch, M Muik, K Kepplinger, ME Hack, ... The Journal of physiology 577 (1), 31-44, 2006 | 124 | 2006 |
| Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells J Madl, J Weghuber, R Fritsch, I Derler, M Fahrner, I Frischauf, B Lackner, ... Journal of Biological Chemistry 285 (52), 41135-41142, 2010 | 123 | 2010 |
| Mechanistic view on domains mediating STIM1–Orai coupling M Fahrner, M Muik, I Derler, R Schindl, R Fritsch, I Frischauf, C Romanin Immunological reviews 231 (1), 99-112, 2009 | 120 | 2009 |
| Cholesterol modulates Orai1 channel function I Derler, I Jardin, PB Stathopulos, M Muik, M Fahrner, V Zayats, ... Science signaling 9 (412), ra10-ra10, 2016 | 100 | 2016 |
| Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant I Derler, M Fahrner, O Carugo, M Muik, J Bergsmann, R Schindl, ... Journal of biological chemistry 284 (23), 15903-15915, 2009 | 88 | 2009 |
| Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel R Schindl, I Frischauf, J Bergsmann, M Muik, I Derler, B Lackner, ... Proceedings of the National Academy of Sciences 106 (46), 19623-19628, 2009 | 83 | 2009 |
| The STIM1/Orai signaling machinery M Fahrner, I Derler, I Jardin, C Romanin Channels 7 (5), 330-343, 2013 | 74 | 2013 |
| A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca2+ permeation and SOCE-induced gene transcription I Frischauf, V Zayats, M Deix, A Hochreiter, I Jardin, M Muik, B Lackner, ... Science signaling 8 (408), ra131-ra131, 2015 | 72 | 2015 |
