|Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors|
KS Siveen, S Sikka, R Surana, X Dai, J Zhang, AP Kumar, BKH Tan, ...
Biochimica et Biophysica Acta (BBA)-reviews on cancer 1845 (2), 136-154, 2014
|Role of macrophages in tumour progression|
KS Siveen, G Kuttan
Immunology letters 123 (2), 97-102, 2009
|Analysis of the intricate relationship between chronic inflammation and cancer|
EZP Chai, KS Siveen, MK Shanmugam, F Arfuso, G Sethi
Biochemical Journal 468 (1), 1-15, 2015
|Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse …|
KS Siveen, N Mustafa, F Li, R Kannaiyan, KS Ahn, AP Kumar, WJ Chng, ...
Oncotarget 5 (3), 634, 2014
|Vascular endothelial growth factor (VEGF) signaling in tumour vascularization: potential and challenges|
K Sivaraman Siveen, K Prabhu, R Krishnankutty, S Kuttikrishnan, ...
Current Vascular Pharmacology 15 (4), 339-351, 2017
|Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer|
L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ...
Journal of Biological Chemistry 287 (45), 38028-38040, 2012
|Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer|
KA Manu, MK Shanmugam, L Ramachandran, F Li, KS Siveen, ...
Cancer Letters 363 (1), 28-36, 2015
|γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model|
KS Siveen, KS Ahn, TH Ong, MK Shanmugam, F Li, WN Yap, AP Kumar, ...
Oncotarget 5 (7), 1897, 2014
|Nimbolide-induced oxidative stress abrogates STAT3 signaling cascade and inhibits tumor growth in transgenic adenocarcinoma of mouse prostate model|
J Zhang, KS Ahn, C Kim, MK Shanmugam, KS Siveen, F Arfuso, ...
Antioxidants & redox signaling 24 (11), 575-589, 2016
|Targeting acute myeloid leukemia stem cell signaling by natural products|
KS Siveen, S Uddin, RM Mohammad
Molecular cancer 16 (1), 1-12, 2017
|Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products|
KA Manu, MK Shanmugam, F Li, L Chen, KS Siveen, KS Ahn, AP Kumar, ...
Journal of molecular medicine 92 (3), 267-276, 2014
|microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer|
JN Goh, SY Loo, A Datta, KS Siveen, WN Yap, W Cai, EM Shin, C Wang, ...
Biological Reviews 91 (2), 409-428, 2016
|Silymarin and hepatocellular carcinoma: a systematic, comprehensive, and critical review|
JK Mastron, KS Siveen, G Sethi, A Bishayee
Anti-Cancer Drugs 26 (5), 475-486, 2015
|Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives|
NR Parikh, A Mandal, D Bhatia, KS Siveen, G Sethi, A Bishayee
Phytochemistry reviews 13 (4), 793-810, 2014
|RAS-mediated oncogenic signaling pathways in human malignancies|
AQ Khan, S Kuttikrishnan, KS Siveen, KS Prabhu, M Shanmugakonar, ...
Seminars in Cancer Biology 54, 1-13, 2019
|Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3|
X Dai, KS Ahn, C Kim, KS Siveen, TH Ong, MK Shanmugam, F Li, J Shi, ...
Molecular oncology 9 (4), 818-833, 2015
|Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo|
HK Keerthy, CD Mohan, KS Siveen, JE Fuchs, S Rangappa, ...
Journal of Biological Chemistry 289 (46), 31879-31890, 2014
|Role of non receptor tyrosine kinases in hematological malignances and its targeting by natural products|
KS Siveen, KS Prabhu, IW Achkar, S Kuttikrishnan, S Shyam, AQ Khan, ...
Molecular cancer 17 (1), 1-21, 2018
|Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model|
MK Shanmugam, P Rajendran, F Li, C Kim, S Sikka, KS Siveen, ...
Molecular carcinogenesis 54 (10), 971-985, 2015
|Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers|
F Li, MK Shanmugam, KS Siveen, F Wang, TH Ong, SY Loo, ...
Oncotarget 6 (7), 5147, 2015