SARS-CoV-2 Nsp5 demonstrates two distinct mechanisms targeting RIG-I and MAVS to evade the innate immune response Y Liu, C Qin, Y Rao, C Ngo, JJ Feng, J Zhao, S Zhang, TY Wang, ... MBio 12 (5), 10.1128/mbio. 02335-21, 2021 | 64 | 2021 |
Adenosine receptor signaling targets both PKA and Epac pathways to polarize dendritic cells to a suppressive phenotype M Kayhan, A Koyas, I Akdemir, AC Savas, C Cekic The Journal of Immunology 203 (12), 3247-3255, 2019 | 30 | 2019 |
Deamidation shunts RelA from mediating inflammation to aerobic glycolysis J Zhao, M Tian, S Zhang, A Delfarah, R Gao, Y Rao, AC Savas, A Lu, ... Cell metabolism 31 (5), 937-955. e7, 2020 | 24 | 2020 |
SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis C Qin, Y Rao, H Yuan, TY Wang, J Zhao, B Espinosa, Y Liu, S Zhang, ... Proceedings of the National Academy of Sciences 119 (26), e2122897119, 2022 | 17 | 2022 |
Interleukin-7 protects CD8+ T cells from adenosine-mediated immunosuppression A Koyas, S Tucer, M Kayhan, AC Savas, I Akdemir, C Cekic Science Signaling 14 (674), eabb1269, 2021 | 16 | 2021 |
Targeting CTP synthetase 1 to restore interferon induction and impede nucleotide synthesis in SARS-CoV-2 infection Y Rao, TY Wang, C Qin, B Espinosa, Q Liu, A Ekanayake, J Zhao, ... BioRxiv, 2021 | 13 | 2021 |
SARS-CoV-2 Nsp5 demonstrates two distinct mechanisms targeting RIG-I and MAVS to evade the innate immune response. mBio 12: e0233521 Y Liu, C Qin, Y Rao, C Ngo, JJ Feng, J Zhao, S Zhang, TY Wang, ... | 11 | 2021 |
Viral pseudoenzymes in infection and immunity TY Wang, J Zhao, AC Savas, S Zhang, P Feng The FEBS journal 287 (19), 4300-4309, 2020 | 6 | 2020 |
Molecular mechanism for adenosine regulation of dendritic cells C Cekic, M Kayhan, A Koyas, I Akdemir, AC Savas The Journal of Immunology 198 (1_Supplement), 67.8-67.8, 2017 | 3 | 2017 |
Molecular mechanisms for adenosine regulation of helper T cell activation C Cekic, I Akdemir, A Koyas, M Kayhan, AC Savas The Journal of Immunology 198 (1_Supplement), 52.22-52.22, 2017 | 1 | 2017 |
Enzyme inhibitors and viral infection therapy F Pinghui, C Zhang, J Zhao, B Espinosa, C Qin, A Savas, RAO Youliang, ... US Patent App. 18/263,582, 2024 | | 2024 |
Metabolic Enzymes in Viral Infection and Host Innate Immunity C Qin, T Xie, WW Yeh, AC Savas, P Feng Viruses 16 (1), 35, 2023 | | 2023 |
The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection S Zhang, N Xie, Y Liu, C Qin, AC Savas, T Wang, S Li, Y Rao, ... bioRxiv, 2023 | | 2023 |
Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection (preprint) Y Rao, TY Wang, C Qin, B Espinosa, Q Liu, A Ekanayake, J Zhao, ... | | 2021 |
Ectopic expression of CD127 restores the numbers of thymic and peripheral T cell populations in adenosine A2A receptor deficient mouse C Cekic, JM Linden, AC Savas, M Kayhan, A Koyas, I Akdemir The Journal of Immunology 198 (1_Supplement), 76.25-76.25, 2017 | | 2017 |
Targeting adenosine A2A receptors to improve vaccine efficacy C Cekic, AC Savas, M Kayhan, A Koyas, I Akdemir The Journal of Immunology 198 (1_Supplement), 79.22-79.22, 2017 | | 2017 |
Adenosine regulation of danger signaling C Cekic, I Akdemir, A Koyas, M Kayhan, AC Savas The Journal of Immunology 198 (1_Supplement), 222.14-222.14, 2017 | | 2017 |
Targeting adenosine receptors to improve vaccine efficacy AC Savaş PQDT-Global, 2016 | | 2016 |