Christine A. Iacobuzio-Donahue
Christine A. Iacobuzio-Donahue
Verified email at mskcc.org - Homepage
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Year
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
38562008
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
27842009
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ...
Nature 467 (7319), 1114-1117, 2010
23232010
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
19732011
A draft map of the human proteome
MS Kim, SM Pinto, D Getnet, RS Nirujogi, SS Manda, R Chaerkady, ...
Nature 509 (7502), 575-581, 2014
18052014
Genomic analyses identify molecular subtypes of pancreatic cancer
P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ...
Nature 531 (7592), 47-52, 2016
16622016
Whole genomes redefine the mutational landscape of pancreatic cancer
N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ...
Nature 518 (7540), 495-501, 2015
16602015
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
16322012
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
15862011
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ...
Nature 467 (7319), 1109-1113, 2010
12852010
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ...
Cancer cell 25 (6), 735-747, 2014
12372014
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1-2), 324-338, 2015
10152015
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ...
Journal of clinical oncology 27 (11), 1806, 2009
9142009
Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma
RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ...
Nature genetics 47 (10), 1168, 2015
8362015
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
8092009
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
G Feldmann, S Dhara, V Fendrich, D Bedja, R Beaty, M Mullendore, ...
Cancer research 67 (5), 2187-2196, 2007
7762007
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
Y Miyamoto, A Maitra, B Ghosh, U Zechner, P Argani, ...
Cancer cell 3 (6), 565-576, 2003
7512003
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression
RE Wilentz, CA Iacobuzio-Donahue, P Argani, DM McCarthy, JL Parsons, ...
Cancer research 60 (7), 2002-2006, 2000
7092000
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene …
P Argani, C Iacobuzio-Donahue, B Ryu, C Rosty, M Goggins, RE Wilentz, ...
Clinical cancer research 7 (12), 3862-3868, 2001
6122001
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
Y He, J Wu, DC Dressman, C Iacobuzio-Donahue, SD Markowitz, ...
Nature 464 (7288), 610-614, 2010
5332010
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