| Heteroaromatic π-stacking energy landscapes RG Huber, MA Margreiter, JE Fuchs, S von Grafenstein, CS Tautermann, ... Journal of chemical information and modeling 54 (5), 1371-1379, 2014 | 187 | 2014 |
| Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo CD Mohan, H Bharathkumar, KC Bulusu, V Pandey, S Rangappa, ... Journal of Biological Chemistry 289 (49), 34296-34307, 2014 | 171 | 2014 |
| DPPC-cholesterol phase diagram using coarse-grained Molecular Dynamics simulations Y Wang, P Gkeka, JE Fuchs, KR Liedl, Z Cournia Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (11), 2846-2857, 2016 | 135 | 2016 |
| A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo C Kofink, N Trainor, B Mair, S Wöhrle, M Wurm, N Mischerikow, MJ Roy, ... Nature Communications 13 (1), 5969, 2022 | 121 | 2022 |
| Start selective and rigidify: the discovery path toward a next generation of EGFR tyrosine kinase inhibitors H Engelhardt, D Böse, M Petronczki, D Scharn, G Bader, A Baum, ... Journal of medicinal chemistry 62 (22), 10272-10293, 2019 | 121 | 2019 |
| Synthesis of 1, 2-benzisoxazole tethered 1, 2, 3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and … N Ashwini, M Garg, CD Mohan, JE Fuchs, S Rangappa, S Anusha, ... Bioorganic & medicinal chemistry 23 (18), 6157-6165, 2015 | 113 | 2015 |
| Rationalizing tight ligand binding through cooperative interaction networks B Kuhn, JE Fuchs, M Reutlinger, M Stahl, NR Taylor Journal of chemical information and modeling 51 (12), 3180-3198, 2011 | 108 | 2011 |
| Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen Y Machado, R Freier, S Scheiblhofer, T Thalhamer, M Mayr, P Briza, ... Journal of Allergy and Clinical Immunology 137 (5), 1525-1534, 2016 | 94 | 2016 |
| The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101 C Ackaert, S Kofler, J Horejs-Hoeck, N Zulehner, C Asam, ... PloS one 9 (8), e104520, 2014 | 94 | 2014 |
| Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3 J Böttcher, D Dilworth, U Reiser, RA Neumüller, M Schleicher, ... Nature chemical biology 15 (8), 822-829, 2019 | 92 | 2019 |
| Inhibition of collagenase by mycosporine-like amino acids from marine sources A Hartmann, J Gostner, JE Fuchs, E Chaita, N Aligiannis, L Skaltsounis, ... Planta Medica 81 (10), 813-820, 2015 | 90 | 2015 |
| Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo HK Keerthy, CD Mohan, KS Siveen, JE Fuchs, S Rangappa, ... Journal of Biological Chemistry 289 (46), 31879-31890, 2014 | 86 | 2014 |
| Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response A Reintjes, JE Fuchs, L Kremser, HH Lindner, KR Liedl, LA Huber, ... Proceedings of the National Academy of Sciences 113 (16), 4326-4331, 2016 | 80 | 2016 |
| Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma M Neelgundmath, KR Dinesh, CD Mohan, F Li, X Dai, KS Siveen, ... Bioorganic & medicinal chemistry letters 25 (4), 893-897, 2015 | 76 | 2015 |
| Matched molecular pair analysis: significance and the impact of experimental uncertainty C Kramer, JE Fuchs, S Whitebread, P Gedeck, KR Liedl Journal of medicinal chemistry 57 (9), 3786-3802, 2014 | 74 | 2014 |
| A gatekeeper helix determines the substrate specificity of Sjögren–Larsson Syndrome enzyme fatty aldehyde dehydrogenase MA Keller, U Zander, JE Fuchs, C Kreutz, K Watschinger, T Mueller, ... Nature communications 5 (1), 4439, 2014 | 70 | 2014 |
| Peptidic macrocycles-conformational sampling and thermodynamic characterization AS Kamenik, U Lessel, JE Fuchs, T Fox, KR Liedl Journal of chemical information and modeling 58 (5), 982-992, 2018 | 68 | 2018 |
| Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting … CL Sutherell, C Tallant, OP Monteiro, C Yapp, JE Fuchs, O Fedorov, ... Journal of Medicinal Chemistry 59 (10), 5095-5101, 2016 | 67 | 2016 |
| PI by NMR: probing CH–π interactions in protein–ligand complexes by NMR spectroscopy G Platzer, M Mayer, A Beier, S Brüschweiler, JE Fuchs, H Engelhardt, ... Angewandte Chemie 132 (35), 14971-14978, 2020 | 64 | 2020 |
| Cleavage entropy as quantitative measure of protease specificity JE Fuchs, S von Grafenstein, RG Huber, MA Margreiter, GM Spitzer, ... PLoS Computational Biology 9 (4), e1003007, 2013 | 60 | 2013 |
Klaus LiedlProfessor for Theoretical Chemistry, University of InnsbruckBestätigte E-Mail-Adresse bei uibk.ac.at
