Julian Fuchs
Zitiert von
Zitiert von
Heteroaromatic π-stacking energy landscapes
RG Huber, MA Margreiter, JE Fuchs, S von Grafenstein, CS Tautermann, ...
Journal of chemical information and modeling 54 (5), 1371-1379, 2014
Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo
CD Mohan, H Bharathkumar, KC Bulusu, V Pandey, S Rangappa, ...
Journal of Biological Chemistry 289 (49), 34296-34307, 2014
DPPC-cholesterol phase diagram using coarse-grained Molecular Dynamics simulations
Y Wang, P Gkeka, JE Fuchs, KR Liedl, Z Cournia
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (11), 2846-2857, 2016
Rationalizing tight ligand binding through cooperative interaction networks
B Kuhn, JE Fuchs, M Reutlinger, M Stahl, NR Taylor
Journal of chemical information and modeling 51 (12), 3180-3198, 2011
Start selective and rigidify: the discovery path toward a next generation of EGFR tyrosine kinase inhibitors
H Engelhardt, D Böse, M Petronczki, D Scharn, G Bader, A Baum, ...
Journal of medicinal chemistry 62 (22), 10272-10293, 2019
Synthesis of 1, 2-benzisoxazole tethered 1, 2, 3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and …
N Ashwini, M Garg, CD Mohan, JE Fuchs, S Rangappa, S Anusha, ...
Bioorganic & medicinal chemistry 23 (18), 6157-6165, 2015
Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
Y Machado, R Freier, S Scheiblhofer, T Thalhamer, M Mayr, P Briza, ...
Journal of Allergy and Clinical Immunology 137 (5), 1525-1534, 2016
The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101
C Ackaert, S Kofler, J Horejs-Hoeck, N Zulehner, C Asam, ...
PloS one 9 (8), e104520, 2014
Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo
HK Keerthy, CD Mohan, KS Siveen, JE Fuchs, S Rangappa, ...
Journal of Biological Chemistry 289 (46), 31879-31890, 2014
Inhibition of collagenase by mycosporine-like amino acids from marine sources
A Hartmann, J Gostner, J Fuchs, E Chaita, N Aligiannis, L Skaltsounis, ...
Planta Medica 81 (10), 813-820, 2015
Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma
M Neelgundmath, KR Dinesh, CD Mohan, F Li, X Dai, KS Siveen, ...
Bioorganic & medicinal chemistry letters 25 (4), 893-897, 2015
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3
J Böttcher, D Dilworth, U Reiser, RA Neumüller, M Schleicher, ...
Nature chemical biology 15 (8), 822-829, 2019
Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response
A Reintjes, JE Fuchs, L Kremser, HH Lindner, KR Liedl, LA Huber, ...
Proceedings of the National Academy of Sciences 113 (16), 4326-4331, 2016
A gatekeeper helix determines the substrate specificity of Sjögren–Larsson Syndrome enzyme fatty aldehyde dehydrogenase
MA Keller, U Zander, JE Fuchs, C Kreutz, K Watschinger, T Mueller, ...
Nature communications 5 (1), 4439, 2014
Matched molecular pair analysis: significance and the impact of experimental uncertainty
C Kramer, JE Fuchs, S Whitebread, P Gedeck, KR Liedl
Journal of medicinal chemistry 57 (9), 3786-3802, 2014
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
C Kofink, N Trainor, B Mair, S Wöhrle, M Wurm, N Mischerikow, MJ Roy, ...
Nature Communications 13 (1), 5969, 2022
Peptidic macrocycles-conformational sampling and thermodynamic characterization
AS Kamenik, U Lessel, JE Fuchs, T Fox, KR Liedl
Journal of chemical information and modeling 58 (5), 982-992, 2018
Cleavage entropy as quantitative measure of protease specificity
JE Fuchs, S von Grafenstein, RG Huber, MA Margreiter, GM Spitzer, ...
PLoS Computational Biology 9 (4), e1003007, 2013
Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting …
CL Sutherell, C Tallant, OP Monteiro, C Yapp, JE Fuchs, O Fedorov, ...
Journal of Medicinal Chemistry 59 (10), 5095-5101, 2016
Identification of protease specificity by combining proteome-derived peptide libraries and quantitative proteomics
ML Biniossek, M Niemer, K Maksimchuk, B Mayer, J Fuchs, PF Huesgen, ...
Molecular & cellular proteomics 15 (7), 2515-2524, 2016
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