Rare-variant association testing for sequencing data with the sequence kernel association test MC Wu, S Lee, T Cai, Y Li, M Boehnke, X Lin The American Journal of Human Genetics 89 (1), 82-93, 2011 | 2724 | 2011 |
Quality of life and satisfaction with outcome among prostate-cancer survivors MG Sanda, RL Dunn, J Michalski, HM Sandler, L Northouse, L Hembroff, ... New England Journal of Medicine 358 (12), 1250-1261, 2008 | 2631 | 2008 |
Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study LH Nguyen, DA Drew, MS Graham, AD Joshi, CG Guo, W Ma, RS Mehta, ... The Lancet Public Health 5 (9), e475-e483, 2020 | 2592 | 2020 |
Association of public health interventions with the epidemiology of the COVID-19 outbreak in Wuhan, China A Pan, L Liu, C Wang, H Guo, X Hao, Q Wang, J Huang, N He, H Yu, X Lin, ... Jama 323 (19), 1915-1923, 2020 | 1886 | 2020 |
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ... Nature 590 (7845), 290-299, 2021 | 1524 | 2021 |
LKB1 modulates lung cancer differentiation and metastasis H Ji, MR Ramsey, DN Hayes, C Fan, K McNamara, P Kozlowski, C Torrice, ... Nature 448 (7155), 807-810, 2007 | 1193 | 2007 |
Rare-variant association analysis: study designs and statistical tests S Lee, GR Abecasis, M Boehnke, X Lin The American Journal of Human Genetics 95 (1), 5-23, 2014 | 1171 | 2014 |
Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies S Lee, MJ Emond, MJ Bamshad, KC Barnes, MJ Rieder, DA Nickerson, ... The American Journal of Human Genetics 91 (2), 224-237, 2012 | 1105 | 2012 |
Inference in generalized additive mixed models by using smoothing splines X Lin, D Zhang Journal of the Royal Statistical Society Series B: Statistical Methodology …, 1999 | 787 | 1999 |
Optimal tests for rare variant effects in sequencing association studies S Lee, MC Wu, X Lin Biostatistics 13 (4), 762-775, 2012 | 785 | 2012 |
Rising rural body-mass index is the main driver of the global obesity epidemic in adults Nature 569 (7755), 260-264, 2019 | 778 | 2019 |
Powerful SNP-set analysis for case-control genome-wide association studies MC Wu, P Kraft, MP Epstein, DM Taylor, SJ Chanock, DJ Hunter, X Lin The American Journal of Human Genetics 86 (6), 929-942, 2010 | 707 | 2010 |
A century of trends in adult human height NCD Risk Factor Collaboration (NCD-RisC) elife 5, e13410, 2016 | 649 | 2016 |
Bias correction in generalised linear mixed models with a single component of dispersion NE Breslow, X Lin Biometrika 82 (1), 81-91, 1995 | 642 | 1995 |
Bias correction in generalized linear mixed models with multiple components of dispersion X Lin, NE Breslow Journal of the American Statistical Association 91 (435), 1007-1016, 1996 | 554 | 1996 |
Sequence kernel association tests for the combined effect of rare and common variants I Ionita-Laza, S Lee, V Makarov, JD Buxbaum, X Lin The American Journal of Human Genetics 92 (6), 841-853, 2013 | 505 | 2013 |
Reconstruction of the full transmission dynamics of COVID-19 in Wuhan X Hao, S Cheng, D Wu, T Wu, X Lin, C Wang Nature 584 (7821), 420-424, 2020 | 463 | 2020 |
The trans-ancestral genomic architecture of glycemic traits J Chen, CN Spracklen, G Marenne, A Varshney, LJ Corbin, J Luan, ... Nature genetics 53 (6), 840-860, 2021 | 456 | 2021 |
Variance component testing in generalised linear models with random effects X Lin Biometrika 84 (2), 309-326, 1997 | 436 | 1997 |
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ... Nature genetics 50 (4), 559-571, 2018 | 434 | 2018 |