Robert L Bowman
Robert L Bowman
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CSF-1R inhibition alters macrophage polarization and blocks glioma progression
SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ...
Nature medicine 19 (10), 1264-1272, 2013
Human iPSC-based modeling of late-onset disease via progerin-induced aging
JD Miller, YM Ganat, S Kishinevsky, RL Bowman, B Liu, EY Tu, ...
Cell stem cell 13 (6), 691-705, 2013
GlioVis data portal for visualization and analysis of brain tumor expression datasets
RL Bowman, Q Wang, A Carro, RGW Verhaak, M Squatrito
Neuro-oncology 19 (1), 139-141, 2017
Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells
F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ...
Cell 181 (7), 1643-1660. e17, 2020
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
DF Quail, RL Bowman, L Akkari, ML Quick, AJ Schuhmacher, JT Huse, ...
Science 352 (6288), aad3018, 2016
Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies
RL Bowman, F Klemm, L Akkari, SM Pyonteck, L Sevenich, DF Quail, ...
Cell reports 17 (9), 2445-2459, 2016
Clonal hematopoiesis and evolution to hematopoietic malignancies
RL Bowman, L Busque, RL Levine
Cell stem cell 22 (2), 157-170, 2018
Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
L Sevenich, RL Bowman, SD Mason, DF Quail, F Rapaport, BT Elie, ...
Nature cell biology 16 (9), 876-888, 2014
Single-cell mutation analysis of clonal evolution in myeloid malignancies
LA Miles, RL Bowman, TR Merlinsky, IS Csete, AT Ooi, ...
Nature 587 (7834), 477-482, 2020
Adipocyte-derived lipids mediate melanoma progression via FATP proteins
M Zhang, JS Di Martino, RL Bowman, NR Campbell, SC Baksh, ...
Cancer discovery 8 (8), 1006-1025, 2018
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance
L Akkari, RL Bowman, J Tessier, F Klemm, SM Handgraaf, M de Groot, ...
Science translational medicine 12 (552), eaaw7843, 2020
Self-renewal of CD133hi cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer
P Sansone, C Ceccarelli, M Berishaj, Q Chang, VK Rajasekhar, F Perna, ...
Nature communications 7 (1), 10442, 2016
STAT3 and STAT6 signaling pathways synergize to promote cathepsin secretion from macrophages via IRE1α activation
D Yan, HW Wang, RL Bowman, JA Joyce
Cell reports 16 (11), 2914-2927, 2016
Microenvironment-derived factors driving metastatic plasticity in melanoma
IS Kim, S Heilmann, ER Kansler, Y Zhang, M Zimmer, K Ratnakumar, ...
Nature communications 8 (1), 14343, 2017
Evolution of cancer stem-like cells in endocrine-resistant metastatic breast cancers is mediated by stromal microvesicles
P Sansone, M Berishaj, VK Rajasekhar, C Ceccarelli, Q Chang, ...
Cancer research 77 (8), 1927-1941, 2017
Cohesin members Stag1 and Stag2 display distinct roles in chromatin accessibility and topological control of HSC self-renewal and differentiation
AD Viny, RL Bowman, Y Liu, VP Lavallée, SE Eisman, W Xiao, ...
Cell stem cell 25 (5), 682-696. e8, 2019
Epigenetic identity in AML depends on disruption of nonpromoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers
JL Glass, D Hassane, BJ Wouters, H Kunimoto, R Avellino, ...
Cancer discovery 7 (8), 868-883, 2017
Microglia promote glioblastoma via mTOR‐mediated immunosuppression of the tumour microenvironment
AA Dumas, N Pomella, G Rosser, L Guglielmi, C Vinel, TO Millner, J Rees, ...
The EMBO journal 39 (15), e103790, 2020
TET2 in normal and malignant hematopoiesis
RL Bowman, RL Levine
Cold Spring Harbor Perspectives in Medicine 7 (8), a026518, 2017
Jak1 integrates cytokine sensing to regulate hematopoietic stem cell function and stress hematopoiesis
M Kleppe, MH Spitzer, S Li, CE Hill, L Dong, E Papalexi, S De Groote, ...
Cell stem cell 21 (4), 489-501. e7, 2017
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