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Casey Krusemark
Casey Krusemark
Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University
Verified email at purdue.edu - Homepage
Title
Cited by
Cited by
Year
Spleen tyrosine kinase–mediated autophagy is required for epithelial–mesenchymal plasticity and metastasis in breast cancer
A Shinde, SD Hardy, D Kim, SS Akhand, MK Jolly, WH Wang, ...
Cancer research 79 (8), 1831-1843, 2019
1032019
Selection of DNA-encoded libraries to protein targets within and on living cells
B Cai, D Kim, S Akhand, Y Sun, RJ Cassell, A Alpsoy, EC Dykhuizen, ...
Journal of the American Chemical Society 141 (43), 17057-17061, 2019
962019
Modifying the charge state distribution of proteins in electrospray ionization mass spectrometry by chemical derivatization
CJ Krusemark, BL Frey, PJ Belshaw, LM Smith
Journal of the American Society for Mass Spectrometry 20, 1617-1625, 2009
962009
Mixed isotope photoaffinity reagents for identification of small‐molecule targets by mass spectrometry
SM Lamos, CJ Krusemark, CJ McGee, M Scalf, LM Smith, PJ Belshaw
Angewandte Chemie 118 (26), 4435-4439, 2006
632006
Optimization of ligands using focused DNA-encoded libraries to develop a selective, cell-permeable CBX8 chromodomain inhibitor
S Wang, KE Denton, KF Hobbs, T Weaver, JMB McFarlane, KE Connelly, ...
ACS chemical biology 15 (1), 112-131, 2019
582019
Crosslinking of DNA-linked ligands to target proteins for enrichment from DNA-encoded libraries
KE Denton, CJ Krusemark
MedChemComm 7 (10), 2020-2027, 2016
582016
Chemical derivatization of peptide carboxyl groups for highly efficient electron transfer dissociation
BL Frey, DT Ladror, SB Sondalle, CJ Krusemark, AL Jue, JJ Coon, ...
Journal of the American Society for Mass Spectrometry 24 (11), 1710-1721, 2013
552013
Robustness of in vitro selection assays of DNA-encoded peptidomimetic ligands to CBX7 and CBX8
KE Denton, S Wang, MC Gignac, N Milosevich, F Hof, EC Dykhuizen, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 23 (5), 417-428, 2018
532018
Global amine and acid functional group modification of proteins
CJ Krusemark, JT Ferguson, CD Wenger, NL Kelleher, PJ Belshaw
Analytical chemistry 80 (3), 713-720, 2008
312008
Directed chemical evolution with an outsized genetic code
CJ Krusemark, NP Tilmans, PO Brown, PB Harbury
PLoS One 11 (8), e0154765, 2016
302016
A potent, selective CBX2 chromodomain ligand and its cellular activity during prostate cancer neuroendocrine differentiation
S Wang, A Alpsoy, S Sood, SC Ordonez‐Rubiano, A Dhiman, Y Sun, ...
ChemBioChem 22 (13), 2335-2344, 2021
292021
Sensing Enzymatic Activity by Exposure and Selection of DNA‐Encoded Probes
RR Jetson, CJ Krusemark
Angewandte Chemie International Edition 55 (33), 9562-9566, 2016
292016
Ion–ion reactions with fixed-charge modified proteins to produce ions in a single, very high charge state
BL Frey, CJ Krusemark, AR Ledvina, JJ Coon, PJ Belshaw, LM Smith
International journal of mass spectrometry 276 (2-3), 136-143, 2008
262008
Complete chemical modification of amine and acid functional groups of peptides and small proteins
CJ Krusemark, BL Frey, LM Smith, PJ Belshaw
Gel-Free Proteomics: Methods and Protocols, 77-91, 2011
232011
Ionizable isotopic labeling reagents for relative quantification by mass spectrometry
LM Smith, MR Shortreed, BL Frey, MF Phillips, JJ Coon, SM Lamos, ...
US Patent 7,982,070, 2011
192011
Covalent labelling of fusion proteins in live cells via an engineered receptor–ligand pair
CJ Krusemark, PJ Belshaw
Organic & Biomolecular Chemistry 5 (14), 2201-2204, 2007
182007
Multiplexed Small‐Molecule‐Ligand Binding Assays by Affinity Labeling and DNA Sequence Analysis
B Cai, CJ Krusemark
Angewandte Chemie International Edition 61 (3), e202113515, 2022
162022
Application of a substrate-mediated selection with c-Src tyrosine kinase to a DNA-encoded chemical library
D Kim, Y Sun, D Xie, KE Denton, H Chen, H Lin, MK Wendt, CB Post, ...
Molecules 24 (15), 2764, 2019
152019
A DNA-assisted immunoassay for enzyme activity via a DNA-linked, activity-based probe
D Kim, RR Jetson, CJ Krusemark
Chemical Communications 53 (68), 9474-9477, 2017
122017
Selection methods for proximity-dependent enrichment of ligands from DNA-encoded libraries using enzymatic fusion proteins
B Cai, AB Mhetre, CJ Krusemark
Chemical Science 14 (2), 245-250, 2023
92023
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