| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13146* | 2021 |
| Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease: a 3 year longitudinal study T Baba, A Kikuchi, K Hirayama, Y Nishio, Y Hosokai, S Kanno, ... Brain 135 (1), 161-169, 2012 | 309 | 2012 |
| Asymmetric membrane ganglioside sialidase activity specifies axonal fate JS Da Silva, T Hasegawa, T Miyagi, CG Dotti, J Abad-Rodriguez Nature neuroscience 8 (5), 606-615, 2005 | 263 | 2005 |
| Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson’s disease pathogenesis I Carballo-Carbajal, A Laguna, J Romero-Giménez, T Cuadros, J Bové, ... Nature communications 10 (1), 973, 2019 | 258 | 2019 |
| Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair O Rothfuss, H Fischer, T Hasegawa, M Maisel, P Leitner, F Miesel, ... Human molecular genetics 18 (20), 3832-3850, 2009 | 229 | 2009 |
| VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease E Miura, T Hasegawa, M Konno, M Suzuki, N Sugeno, N Fujikake, ... Neurobiology of disease 71, 1-13, 2014 | 196 | 2014 |
| CSF hypovolemia vs intracranial hypotension in “spontaneous intracranial hypotension syndrome” K Miyazawa, Y Shiga, T Hasegawa, M Endoh, N Okita, S Higano, ... Neurology 60 (6), 941-947, 2003 | 185 | 2003 |
| Plasma membrane ganglioside sialidase regulates axonal growth and regeneration in hippocampal neurons in culture JA Rodriguez, E Piddini, T Hasegawa, T Miyagi, CG Dotti Journal of Neuroscience 21 (21), 8387-8395, 2001 | 181 | 2001 |
| Serine 129 phosphorylation of α-synuclein induces unfolded protein response-mediated cell death N Sugeno, A Takeda, T Hasegawa, M Kobayashi, A Kikuchi, F Mori, ... Journal of Biological Chemistry 283 (34), 23179-23188, 2008 | 179 | 2008 |
| Molecular cloning of mouse ganglioside sialidase and its increased expression in Neuro2a cell differentiation T Hasegawa, K Yamaguchi, T Wada, A Takeda, Y Itoyama, T Miyagi Journal of Biological Chemistry 275 (11), 8007-8015, 2000 | 170 | 2000 |
| The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein T Hasegawa, M Konno, T Baba, N Sugeno, A Kikuchi, M Kobayashi, ... PloS one 6 (12), e29460, 2011 | 159 | 2011 |
| Nuclear and neuritic distribution of serine-129 phosphorylated α-synuclein in transgenic mice H Schell, T Hasegawa, M Neumann, PJ Kahle Neuroscience 160 (4), 796-804, 2009 | 146 | 2009 |
| Tyrosinase-Expressing Neuronal Cell Line as in Vitro Model of Parkinson’s Disease T Hasegawa International journal of molecular sciences 11 (3), 1082-1089, 2010 | 140 | 2010 |
| Plasma membrane ion permeability induced by mutant α‐synuclein contributes to the degeneration of neural cells K Furukawa, M Matsuzaki‐Kobayashi, T Hasegawa, A Kikuchi, N Sugeno, ... Journal of neurochemistry 97 (4), 1071-1077, 2006 | 139 | 2006 |
| In vivo visualization of α-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission … A Kikuchi, A Takeda, N Okamura, M Tashiro, T Hasegawa, S Furumoto, ... Brain 133 (6), 1772-1778, 2010 | 134 | 2010 |
| Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy M Konno, T Hasegawa, T Baba, E Miura, N Sugeno, A Kikuchi, FC Fiesel, ... Molecular neurodegeneration 7, 1-16, 2012 | 125 | 2012 |
| In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET A Kikuchi, N Okamura, T Hasegawa, R Harada, S Watanuki, Y Funaki, ... Neurology 87 (22), 2309-2316, 2016 | 123 | 2016 |
| Accelerated α-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells T Hasegawa, M Matsuzaki, A Takeda, A Kikuchi, H Akita, G Perry, ... Brain research 1013 (1), 51-59, 2004 | 110 | 2004 |
| Association of olfactory dysfunction and brain. Metabolism in Parkinson's disease T Baba, A Takeda, A Kikuchi, Y Nishio, Y Hosokai, K Hirayama, ... Movement Disorders 26 (4), 621-628, 2011 | 106 | 2011 |
| Parkin protects against tyrosinase‐mediated dopamine neurotoxicity by suppressing stress‐activated protein kinase pathways T Hasegawa, A Treis, N Patenge, FC Fiesel, W Springer, PJ Kahle Journal of neurochemistry 105 (5), 1700-1715, 2008 | 102 | 2008 |
Atsushi Takeda, M.D. & Ph.D.Director, National Hospital Organization, Sendai-Nishitaga HospitalVerified email at mail.hosp.go.jp
