| Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses F Weber, V Wagner, SB Rasmussen, R Hartmann, SR Paludan Journal of virology 80 (10), 5059-5064, 2006 | 1079 | 2006 |
| Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen … Z Zhou, OJ Hamming, N Ank, SR Paludan, AL Nielsen, R Hartmann Journal of virology 81 (14), 7749-7758, 2007 | 582 | 2007 |
| An important role for type III interferon (IFN-λ/IL-28) in TLR-induced antiviral activity N Ank, MB Iversen, C Bartholdy, P Staeheli, R Hartmann, UB Jensen, ... The Journal of Immunology 180 (4), 2474-2485, 2008 | 547 | 2008 |
| A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells JT Marques, T Devosse, D Wang, M Zamanian-Daryoush, P Serbinowski, ... Nature biotechnology 24 (5), 559-565, 2006 | 511 | 2006 |
| Guarding the frontiers: the biology of type III interferons A Wack, E Terczyńska-Dyla, R Hartmann Nature immunology 16 (8), 802-809, 2015 | 407 | 2015 |
| Type I and III interferons disrupt lung epithelial repair during recovery from viral infection J Major, S Crotta, M Llorian, TM McCabe, HH Gad, SL Priestnall, ... Science 369 (6504), 712-717, 2020 | 377 | 2020 |
| OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids V Hornung, R Hartmann, A Ablasser, KP Hopfner Nature Reviews Immunology 14 (8), 521-528, 2014 | 335 | 2014 |
| The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities H Kristiansen, HH Gad, S Eskildsen-Larsen, P Despres, R Hartmann Journal of Interferon & Cytokine Research 31 (1), 41-47, 2011 | 323 | 2011 |
| Gene structure and function of the 2′-5′-oligoadenylate synthetase family J Justesen, R Hartmann, NO Kjeldgaard Cellular and Molecular Life Sciences CMLS 57, 1593-1612, 2000 | 272 | 2000 |
| The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains D Aggad, M Mazel, P Boudinot, KE Mogensen, OJ Hamming, R Hartmann, ... The Journal of Immunology 183 (6), 3924-3931, 2009 | 263 | 2009 |
| Interferon-λ is functionally an interferon but structurally related to the interleukin-10 family HH Gad, C Dellgren, OJ Hamming, S Vends, SR Paludan, R Hartmann Journal of Biological Chemistry 284 (31), 20869-20875, 2009 | 261 | 2009 |
| IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission J Klinkhammer, D Schnepf, L Ye, M Schwaderlapp, HH Gad, R Hartmann, ... elife 7, e33354, 2018 | 255 | 2018 |
| Inhibition of SARS–CoV-2 by type I and type III interferons U Felgenhauer, A Schoen, HH Gad, R Hartmann, AR Schaubmar, ... Journal of Biological Chemistry 295 (41), 13958-13964, 2020 | 254 | 2020 |
| Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses OJ Hamming, E Terczyńska‐Dyla, G Vieyres, R Dijkman, SE Jørgensen, ... The EMBO journal 32 (23), 3055-3065, 2013 | 248 | 2013 |
| cGAS is activated by DNA in a length‐dependent manner S Luecke, A Holleufer, MH Christensen, KL Jønsson, GA Boni, ... EMBO reports 18 (10), 1707-1715, 2017 | 246 | 2017 |
| IFN λ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFN α treatment S Davidson, TM McCabe, S Crotta, HH Gad, EM Hessel, S Beinke, ... EMBO molecular medicine 8 (9), 1099-1112, 2016 | 245 | 2016 |
| Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor J Zhu, Y Zhang, A Ghosh, RA Cuevas, A Forero, J Dhar, MS Ibsen, ... Immunity 40 (6), 936-948, 2014 | 243 | 2014 |
| COVID-19 and emerging viral infections: The case for interferon lambda L Prokunina-Olsson, N Alphonse, RE Dickenson, JE Durbin, JS Glenn, ... Journal of Experimental Medicine 217 (5), 2020 | 221 | 2020 |
| Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential E Kindler, HR Jónsdóttir, D Muth, OJ Hamming, R Hartmann, R Rodriguez, ... MBio 4 (1), 10.1128/mbio. 00611-12, 2013 | 220 | 2013 |
| Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses CK Holm, SH Rahbek, HH Gad, RO Bak, MR Jakobsen, Z Jiang, ... Nature communications 7 (1), 10680, 2016 | 214 | 2016 |
