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Zi-Ning Lei
Zi-Ning Lei
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Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters
YF Fan, W Zhang, L Zeng, ZN Lei, CY Cai, P Gupta, DH Yang, Q Cui, ...
Cancer letters 421, 186-198, 2018
1082018
Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1-and ABCG2-overexpressing cancer cells
N Ji, Y Yang, CY Cai, ZN Lei, JQ Wang, P Gupta, S Shukla, SV Ambudkar, ...
Cancer letters 440, 82-93, 2019
992019
Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19
ZN Lei, ZX Wu, S Dong, DH Yang, L Zhang, Z Ke, C Zou, ZS Chen
Pharmacology & Therapeutics 216, 107672, 2020
812020
ATP‐binding cassette (ABC) transporters in cancer: A review of recent updates
JQ Wang, ZX Wu, Y Yang, QX Teng, YD Li, ZN Lei, KA Jani, N Kaushal, ...
Journal of Evidence‐Based Medicine 14 (3), 232-256, 2021
772021
Signaling pathways and therapeutic interventions in gastric cancer
ZN Lei, QX Teng, Q Tian, W Chen, Y Xie, K Wu, Q Zeng, L Zeng, Y Pan, ...
Signal Transduction and Targeted Therapy 7 (1), 358, 2022
762022
Discovery of 5-cyano-6-phenylpyrimidin derivatives containing an acylurea moiety as orally bioavailable reversal agents against P-glycoprotein-mediated mutidrug resistance
B Wang, LY Ma, JQ Wang, ZN Lei, P Gupta, YD Zhao, ZH Li, Y Liu, ...
Journal of medicinal chemistry 61 (14), 5988-6001, 2018
632018
Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells
ZX Wu, QX Teng, CY Cai, JQ Wang, ZN Lei, Y Yang, YF Fan, JY Zhang, ...
Biochemical pharmacology 166, 120-127, 2019
572019
Olmutinib (BI1482694/HM61713), a novel epidermal growth factor receptor tyrosine kinase inhibitor, reverses ABCG2-mediated multidrug resistance in cancer cells
W Zhang, YF Fan, CY Cai, JQ Wang, QX Teng, ZN Lei, L Zeng, P Gupta, ...
Frontiers in pharmacology 9, 1097, 2018
562018
Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression
D Liao, W Zhang, P Gupta, ZN Lei, JQ Wang, CY Cai, AAD Vera, L Zhang, ...
Molecules 24 (23), 4383, 2019
542019
VS-4718 antagonizes multidrug resistance in ABCB1-and ABCG2-overexpressing cancer cells by inhibiting the efflux function of ABC transporters
N Ji, Y Yang, CY Cai, ZN Lei, JQ Wang, P Gupta, QX Teng, ZS Chen, ...
Frontiers in Pharmacology 9, 1236, 2018
522018
Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo
AA De Vera, P Gupta, Z Lei, D Liao, S Narayanan, Q Teng, SE Reznik, ...
Cancer letters 442, 91-103, 2019
502019
Ulixertinib (BVD-523) antagonizes ABCB1-and ABCG2-mediated chemotherapeutic drug resistance
N Ji, Y Yang, ZN Lei, CY Cai, JQ Wang, P Gupta, X Xian, DH Yang, ...
Biochemical pharmacology 158, 274-285, 2018
492018
Venetoclax, a BCL-2 Inhibitor, Enhances the Efficacy of Chemotherapeutic Agents in Wild-Type ABCG2-Overexpression-Mediated MDR Cancer Cells
JQ Wang, JY Li, QX Teng, ZN Lei, N Ji, Q Cui, L Zeng, Y Pan, DH Yang, ...
Cancers 12 (2), 466, 2020
442020
Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance
ZX Wu, Y Yang, QX Teng, JQ Wang, ZN Lei, JQ Wang, S Lusvarghi, ...
Cancers 12 (1), 186, 2020
402020
PP2A–AMPKα–HSF1 axis regulates the metal-inducible expression of HSPs and ROS clearance
X Zhu, L Chen, Q Bai, L Ma, D Li, J Zhang, C Gao, Z Lei, Z Zhang, X Xing, ...
Cellular signalling 26 (4), 825-832, 2014
382014
Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells
J Wang, DH Yang, Y Yang, JQ Wang, CY Cai, ZN Lei, QX Teng, ZX Wu, ...
International journal of molecular sciences 21 (4), 1387, 2020
362020
Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis
R Liu, Y Chen, W Fu, S Wang, Y Cui, X Zhao, ZN Lei, A Hettinghouse, ...
Annals of the rheumatic diseases 78 (11), 1524-1535, 2019
362019
Regorafenib antagonizes BCRP-mediated multidrug resistance in colon cancer
YK Zhang, YJ Wang, ZN Lei, GN Zhang, XY Zhang, D Wang, SB Al-Rihani, ...
Cancer letters 442, 104-112, 2019
352019
Sitravatinib, a Tyrosine Kinase Inhibitor, Inhibits the Transport Function of ABCG2 and Restores Sensitivity to Chemotherapy-Resistant Cancer Cells in vitro
Y Yang, N Ji, QX Teng, CY Cai, JQ Wang, ZX Wu, ZN Lei, S Lusvarghi, ...
Frontiers in Oncology 10, 700, 2020
342020
Genetic biomarkers of drug resistance: A compass of prognosis and targeted therapy in acute myeloid leukemia
L Long, YG Assaraf, ZN Lei, H Peng, L Yang, ZS Chen, S Ren
Drug Resistance Updates 52, 100703, 2020
322020
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