Irfan Y. Tamboli
Irfan Y. Tamboli
Asst. Professor, Dept. of Biotechnology, SPPU Pune University
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Statins promote the degradation of extracellular amyloid β-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion
IY Tamboli, E Barth, L Christian, M Siepmann, S Kumar, S Singh, ...
Journal of biological chemistry 285 (48), 37405-37414, 2010
Inhibition of glycosphingolipid biosynthesis reduces secretion of the β-amyloid precursor protein and amyloid β-peptide
IY Tamboli, K Prager, E Barth, M Heneka, K Sandhoff, J Walter
Journal of Biological Chemistry 280 (30), 28110-28117, 2005
Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein
V Venkataramani, C Rossner, L Iffland, S Schweyer, IY Tamboli, J Walter, ...
Journal of Biological Chemistry 285 (14), 10678-10689, 2010
Presenilin-1 L166P mutant human pluripotent stem cell–derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation
P Koch, IY Tamboli, J Mertens, P Wunderlich, J Ladewig, K Stüber, ...
The American journal of pathology 180 (6), 2404-2416, 2012
Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Aβ generation
IY Tamboli, H Hampel, NT Tien, K Tolksdorf, B Breiden, PM Mathews, ...
Journal of Neuroscience 31 (5), 1837-1849, 2011
Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid β-protein in perivascular astrocytes
S Utter, IY Tamboli, J Walter, AR Upadhaya, G Birkenmeier, CU Pietrzik, ...
Journal of Neuropathology & Experimental Neurology 67 (9), 842-856, 2008
Loss of γ-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis
IY Tamboli, K Prager, DR Thal, KM Thelen, I Dewachter, CU Pietrzik, ...
Journal of Neuroscience 28 (46), 12097-12106, 2008
Adaptation of neuronal cells to chronic oxidative stress is associated with altered cholesterol and sphingolipid homeostasis and lysosomal function
AB Clement, M Gamerdinger, IY Tamboli, D Lütjohann, J Walter, I Greeve, ...
Journal of neurochemistry 111 (3), 669-682, 2009
Interaction of melanin with proteins–The importance of an acidic intramelanosomal pH
I Mani, V Sharma, I Tamboli, G Raman
Pigment cell research 14 (3), 170-179, 2001
Trehalose alters subcellular trafficking and the metabolism of the Alzheimer-associated amyloid precursor protein
NT Tien, I Karaca, IY Tamboli, J Walter
Journal of Biological Chemistry 291 (20), 10528-10540, 2016
Critical periods after stroke study: translating animal stroke recovery experiments into a clinical trial
AW Dromerick, MA Edwardson, DF Edwards, ML Giannetti, J Barth, ...
Frontiers in human neuroscience 9, 231, 2015
Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein
I Karaca, IY Tamboli, K Glebov, J Richter, LH Fell, MO Grimm, ...
Journal of Biological Chemistry 289 (24), 16761-16772, 2014
Extracellular proteolysis of apolipoprotein E (apoE) by secreted serine neuronal protease
IY Tamboli, D Heo, GW Rebeck
PLoS One 9 (3), e93120, 2014
Human APOE genotype affects intraneuronal Aβ1–42 accumulation in a lentiviral gene transfer model
W Zhao, SB Dumanis, IY Tamboli, GA Rodriguez, M Jo LaDu, ...
Human molecular genetics 23 (5), 1365-1375, 2014
Presenilin 1 affects focal adhesion site formation and cell force generation via c-Src transcriptional and posttranslational regulation
D Waschbüsch, S Born, V Niediek, N Kirchgessner, IY Tamboli, J Walter, ...
Journal of Biological Chemistry 284 (15), 10138-10149, 2009
Sphingolipid storage impairs autophagic clearance of Alzheimer-associated proteins
IY Tamboli, NT Tien, J Walter
Autophagy 7 (6), 645-646, 2011
Lactoferrin–melanin interaction and its possible implications in melanin polymerization: Crystal structure of the complex formed between mare lactoferrin and melanin monomers …
AK Sharma, S Kumar, V Sharma, A Nagpal, N Singh, I Tamboli, I Mani, ...
Proteins: Structure, Function, and Bioinformatics 45 (3), 229-236, 2001
Modulation of Proteolytic Processing by Glycosphingolipids Generates Amyloid β-Peptide
IY Tamboli, K Prager, E Barth, M Heneka, K Sandhoff, J Walter
Sphingolipid Biology, 319-328, 2006
Role of membrane lipids in regulation of Alzheimer’s disease associated proteins and vice-a-versa
IY Tamboli
Universitäts-und Landesbibliothek Bonn, 2008
Article de périodique (Journal article)
IY Tamboli, K Prager, DR Thal, KM Thelen, I Dewachter, CU Pietrzik, ...
The Journal of Neuroscience 28 (46), 12097-12106, 2008
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