Comprehensive molecular portraits of human breast tumours Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ... Nature 490 (7418), 61-70, 2012 | 9355 | 2012 |
An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor … LA Byers, L Diao, J Wang, P Saintigny, L Girard, M Peyton, L Shen, Y Fan, ... Clinical cancer research 19 (1), 279-290, 2013 | 845 | 2013 |
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia R Garzon, S Volinia, CG Liu, C Fernandez-Cymering, T Palumbo, ... Blood, The Journal of the American Society of Hematology 111 (6), 3183-3189, 2008 | 778 | 2008 |
Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments KA Baggerly, JS Morris, KR Coombes Bioinformatics 20 (5), 777-785, 2004 | 777 | 2004 |
Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic VulnerabilitiesCo-occurring … F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou, P Tong, J Izzo, ... Cancer discovery 5 (8), 860-877, 2015 | 565 | 2015 |
Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells M Sun, Z Estrov, Y Ji, KR Coombes, DH Harris, R Kurzrock Molecular cancer therapeutics 7 (3), 464-473, 2008 | 474 | 2008 |
Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome NT Ihle, LA Byers, ES Kim, P Saintigny, JJ Lee, GR Blumenschein, A Tsao, ... Journal of the National Cancer Institute 104 (3), 228-239, 2012 | 455 | 2012 |
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1 LA Byers, J Wang, MB Nilsson, J Fujimoto, P Saintigny, J Yordy, U Giri, ... Cancer discovery 2 (9), 798-811, 2012 | 433 | 2012 |
Feature extraction and quantification for mass spectrometry in biomedical applications using the mean spectrum JS Morris, KR Coombes, J Koomen, KA Baggerly, R Kobayashi Bioinformatics 21 (9), 1764-1775, 2005 | 405 | 2005 |
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases S Liu, M Umezu-Goto, M Murph, Y Lu, W Liu, F Zhang, S Yu, LC Stephens, ... Cancer cell 15 (6), 539-550, 2009 | 397 | 2009 |
Improved peak detection and quantification of mass spectrometry data acquired from surface‐enhanced laser desorption and ionization by denoising spectra with the undecimated … KR Coombes, S Tsavachidis, JS Morris, KA Baggerly, MC Hung, ... Proteomics 5 (16), 4107-4117, 2005 | 395 | 2005 |
Signal in noise: evaluating reported reproducibility of serum proteomic tests for ovarian cancer KA Baggerly, JS Morris, SR Edmonson, KR Coombes Journal of the National Cancer Institute 97 (4), 307-309, 2005 | 367 | 2005 |
A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal TransitionPan-Cancer EMT … MP Mak, P Tong, L Diao, RJ Cardnell, DL Gibbons, WN William, ... Clinical Cancer Research 22 (3), 609-620, 2016 | 321 | 2016 |
Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology KA Baggerly, KR Coombes The Annals of Applied Statistics, 1309-1334, 2009 | 315 | 2009 |
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival S Rossi, M Shimizu, E Barbarotto, MS Nicoloso, F Dimitri, D Sampath, ... Blood, The Journal of the American Society of Hematology 116 (6), 945-952, 2010 | 284 | 2010 |
Quality control and peak finding for proteomics data collected from nipple aspirate fluid by surface-enhanced laser desorption and ionization KR Coombes, HA Fritsche Jr, C Clarke, JN Chen, KA Baggerly, JS Morris, ... Clinical chemistry 49 (10), 1615-1623, 2003 | 279 | 2003 |
Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery JM Koomen, D Li, L Xiao, TC Liu, KR Coombes, J Abbruzzese, ... Journal of proteome research 4 (3), 972-981, 2005 | 244 | 2005 |
Functional proteomic profiling of AML predicts response and survival SM Kornblau, R Tibes, YH Qiu, W Chen, HM Kantarjian, M Andreeff, ... Blood, The Journal of the American Society of Hematology 113 (1), 154-164, 2009 | 241 | 2009 |
A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers BT Hennessy, Y Lu, AM Gonzalez-Angulo, MS Carey, S Myhre, Z Ju, ... Clinical proteomics 6 (4), 129-151, 2010 | 233 | 2010 |
A comprehensive approach to the analysis of matrix‐assisted laser desorption/ionization‐time of flight proteomics spectra from serum samples KA Baggerly, JS Morris, J Wang, D Gold, LC Xiao, KR Coombes Proteomics 3 (9), 1667-1672, 2003 | 225 | 2003 |