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Lauren J. Rajakovich
Lauren J. Rajakovich
Bestätigte E-Mail-Adresse bei uw.edu - Startseite
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Zitiert von
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Two distinct mechanisms for C–C desaturation by iron (II)-and 2-(oxo) glutarate-dependent oxygenases: Importance of α-heteroatom assistance
NP Dunham, W Chang, AJ Mitchell, RJ Martinie, B Zhang, JA Bergman, ...
Journal of the American Chemical Society 140 (23), 7116-7126, 2018
952018
Metabolic functions of the human gut microbiota: the role of metalloenzymes
LJ Rajakovich, EP Balskus
Natural product reports 36 (4), 593-625, 2019
842019
Substrate-triggered addition of dioxygen to the diferrous cofactor of aldehyde-deformylating oxygenase to form a diferric-peroxide intermediate
ME Pandelia, N Li, H Nørgaard, DM Warui, LJ Rajakovich, W Chang, ...
Journal of the American Chemical Society 135 (42), 15801-15812, 2013
832013
Rapid reduction of the diferric-peroxyhemiacetal intermediate in aldehyde-deformylating oxygenase by a cyanobacterial ferredoxin: Evidence for a free-radical mechanism
LJ Rajakovich, H Nørgaard, DM Warui, W Chang, N Li, SJ Booker, ...
Journal of the American Chemical Society 137 (36), 11695-11709, 2015
622015
Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor
HR Rose, MK Ghosh, AO Maggiolo, CJ Pollock, EJ Blaesi, V Hajj, Y Wei, ...
Biochemistry 57 (18), 2679-2693, 2018
502018
Functional analysis of Bacillus subtilis genes involved in the biosynthesis of 4-thiouridine in tRNA
LJ Rajakovich, J Tomlinson, PC Dos Santos
Journal of bacteriology 194 (18), 4933-4940, 2012
482012
Substrate-triggered Formation of a Peroxo-Fe2 (III/III) Intermediate during Fatty Acid Decarboxylation by UndA
B Zhang, LJ Rajakovich, D Van Cura, EJ Blaesi, AJ Mitchell, CR Tysoe, ...
Journal of the American Chemical Society 141 (37), 14510–14514, 2019
462019
Efficient Delivery of Long-Chain Fatty Aldehydes from the Nostoc punctiforme Acyl–Acyl Carrier Protein Reductase to Its Cognate Aldehyde-Deformylating Oxygenase
DM Warui, ME Pandelia, LJ Rajakovich, C Krebs, JM Bollinger Jr, ...
Biochemistry 54 (4), 1006-1015, 2015
422015
Elucidation of an anaerobic pathway for metabolism of L-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteria
LJ Rajakovich, B Fu, M Bollenbach, EP Balskus
Proceedings of the National Academy of Sciences 118 (32), e2101498118, 2021
392021
A new microbial pathway for organophosphonate degradation catalyzed by two previously misannotated non-heme-iron oxygenases
LJ Rajakovich, ME Pandelia, AJ Mitchell, W Chang, B Zhang, AK Boal, ...
Biochemistry 58 (12), 1627-1647, 2019
382019
Hydrogen donation but not abstraction by a tyrosine (Y68) during endoperoxide installation by verruculogen synthase (FtmOx1)
NP Dunham, JM Del Río Pantoja, B Zhang, LJ Rajakovich, BD Allen, ...
Journal of the American Chemical Society 141 (25), 9964-9979, 2019
352019
O–H activation by an unexpected ferryl intermediate during catalysis by 2-hydroxyethylphosphonate dioxygenase
SC Peck, C Wang, LMK Dassama, B Zhang, Y Guo, LJ Rajakovich, ...
Journal of the American Chemical Society 139 (5), 2045-2052, 2017
342017
Emerging structural and functional diversity in proteins with dioxygen-reactive dinuclear transition metal cofactors
LJ Rajakovich, B Zhang, MJ McBride, AK Boal, C Krebs, JM Bollinger Jr
Comprehensive Natural Products III, 3rd Edition: Chemistry & Biology, 215-250, 2020
182020
Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants
JR Chekan, C Ongpipattanakul, TR Wright, B Zhang, JM Bollinger Jr, ...
Proceedings of the National Academy of Sciences 116 (27), 13299-13304, 2019
182019
Mechanism of the Multistep Catalytic Cycle of 6-Hydroxynicotinate 3-Monooxygenase Revealed by Global Kinetic Analysis
SW Perkins, MZ Hlaing, KA Hicks, LJ Rajakovich, MJ Snider
Biochemistry 62 (10), 1553-1567, 2023
22023
Exploring the functional and mechanistic diversity of diiron oxidases and oxygenases
LJ Rajakovich
The Pennsylvania State University, 2017
22017
Long chain acyl-CoA dehydrogenase deficiency: a new inborn error of metabolism manifesting as congenital surfactant deficiency
KR Suhrie, L Rajakovich, AW Mohsen, J Vockley
MOLECULAR GENETICS AND METABOLISM 102 (3), 251-252, 2011
12011
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