Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 5466* | 2012 |
The treatment-naive microbiome in new-onset Crohn’s disease D Gevers, S Kugathasan, LA Denson, Y Vázquez-Baeza, W Van Treuren, ... Cell host & microbe 15 (3), 382-392, 2014 | 3438 | 2014 |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118-1125, 2010 | 3200 | 2010 |
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases J Lloyd-Price, C Arze, AN Ananthakrishnan, M Schirmer, J Avila-Pacheco, ... Nature 569 (7758), 655-662, 2019 | 2183 | 2019 |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246-252, 2011 | 1744 | 2011 |
Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn’s disease in children J Hyams, W Crandall, S Kugathasan, A Griffiths, A Olson, J Johanns, ... Gastroenterology 132 (3), 863-873, 2007 | 1060 | 2007 |
Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study S Kugathasan, RH Judd, RG Hoffmann, J Heikenen, G Telega, F Khan, ... The Journal of pediatrics 143 (4), 525-531, 2003 | 702 | 2003 |
Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy JC Martin, C Chang, G Boschetti, R Ungaro, M Giri, JA Grout, K Gettler, ... Cell 178 (6), 1493-1508. e20, 2019 | 666 | 2019 |
A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients AB Hall, M Yassour, J Sauk, A Garner, X Jiang, T Arthur, GK Lagoudas, ... Genome medicine 9, 1-12, 2017 | 631 | 2017 |
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study S Kugathasan, LA Denson, TD Walters, MO Kim, UM Marigorta, ... The Lancet 389 (10080), 1710-1718, 2017 | 594 | 2017 |
Common variants at five new loci associated with early-onset inflammatory bowel disease M Imielinski, RN Baldassano, A Griffiths, RK Russell, V Annese, ... Nature genetics 41 (12), 1335-1340, 2009 | 584 | 2009 |
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature Y Haberman, TL Tickle, PJ Dexheimer, MO Kim, D Tang, R Karns, ... The Journal of clinical investigation 124 (8), 3617-3633, 2014 | 556 | 2014 |
A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease A Bousvaros, S Guandalini, RN Baldassano, C Botelho, J Evans, ... Inflammatory bowel diseases 11 (9), 833-839, 2005 | 514 | 2005 |
Dynamics of metatranscription in the inflammatory bowel disease gut microbiome M Schirmer, EA Franzosa, J Lloyd-Price, LJ McIver, R Schwager, ... Nature microbiology 3 (3), 337-346, 2018 | 501 | 2018 |
Genetics of inflammatory bowel diseases DPB McGovern, S Kugathasan, JH Cho Gastroenterology 149 (5), 1163-1176. e2, 2015 | 490 | 2015 |
Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology … A Bousvaros, DA Antonioli, RB Colletti, MC Dubinsky, JN Glickman, ... Journal of pediatric gastroenterology and nutrition 44 (5), 653-674, 2007 | 487 | 2007 |
Safety, tolerability, and clinical response after fecal transplantation in children and young adults with ulcerative colitis S Kunde, A Pham, S Bonczyk, T Crumb, M Duba, H Conrad Jr, D Cloney, ... Journal of pediatric gastroenterology and nutrition 56 (6), 597-601, 2013 | 455 | 2013 |
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease S Kugathasan, RN Baldassano, JP Bradfield, PMA Sleiman, M Imielinski, ... Nature genetics 40 (10), 1211-1215, 2008 | 416 | 2008 |
Evaluation of the pediatric Crohn disease activity index: a prospective multicenter experience J Hyams, J Markowitz, A Otley, J Rosh, D Mack, A Bousvaros, ... Journal of pediatric gastroenterology and nutrition 41 (4), 416-421, 2005 | 388 | 2005 |
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease K Wang, H Zhang, S Kugathasan, V Annese, JP Bradfield, RK Russell, ... The American Journal of Human Genetics 84 (3), 399-405, 2009 | 355 | 2009 |