EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features T Yamashita, J Ji, A Budhu, M Forgues, W Yang, HY Wang, H Jia, Q Ye, ... Gastroenterology 136 (3), 1012-1024. e4, 2009 | 1350 | 2009 |
Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells C Ma, M Han, B Heinrich, Q Fu, Q Zhang, M Sandhu, D Agdashian, ... Science 360 (6391), eaan5931, 2018 | 1169 | 2018 |
Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning QH Ye, LX Qin, M Forgues, P He, JW Kim, AC Peng, R Simon, Y Li, ... Nature medicine 9 (4), 416-423, 2003 | 1087 | 2003 |
MicroRNA expression, survival, and response to interferon in liver cancer J Ji, J Shi, A Budhu, Z Yu, M Forgues, S Roessler, S Ambs, Y Chen, ... New England Journal of Medicine 361 (15), 1437-1447, 2009 | 1060 | 2009 |
Centrosome amplification and a defective G2–M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform–deficient cells X Xu, Z Weaver, SP Linke, C Li, J Gotay, XW Wang, CC Harris, T Ried, ... Molecular cell 3 (3), 389-395, 1999 | 1010 | 1999 |
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice RH Wang, K Sengupta, C Li, HS Kim, L Cao, C Xiao, S Kim, X Xu, ... Cancer cell 14 (4), 312-323, 2008 | 966 | 2008 |
Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment A Budhu, M Forgues, QH Ye, HL Jia, P He, KA Zanetti, US Kammula, ... Cancer cell 10 (2), 99-111, 2006 | 954 | 2006 |
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients S Roessler, HL Jia, A Budhu, M Forgues, QH Ye, JS Lee, ... Cancer research 70 (24), 10202-10212, 2010 | 953 | 2010 |
Identification of metastasis‐related microRNAs in hepatocellular carcinoma A Budhu, HL Jia, M Forgues, CG Liu, D Goldstein, A Lam, KA Zanetti, ... Hepatology 47 (3), 897-907, 2008 | 934 | 2008 |
EpCAM and α-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma T Yamashita, M Forgues, W Wang, JW Kim, Q Ye, H Jia, A Budhu, ... Cancer research 68 (5), 1451-1461, 2008 | 902 | 2008 |
Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. XW Wang, K Forrester, H Yeh, MA Feitelson, JR Gu, CC Harris Proceedings of the National Academy of Sciences 91 (6), 2230-2234, 1994 | 886 | 1994 |
GADD45 induction of a G2/M cell cycle checkpoint XW Wang, Q Zhan, JD Coursen, MA Khan, HU Kontny, L Yu, ... Proceedings of the National Academy of Sciences 96 (7), 3706-3711, 1999 | 842 | 1999 |
TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer SP Hussain, J Schwank, F Staib, XW Wang, CC Harris Oncogene 26 (15), 2166-2176, 2007 | 734 | 2007 |
p53 modulation of TFIIH–associated nucleotide excision repair activity XW Wang, H Yeh, L Schaeffer, R Roy, V Moncollin, JM Egly, Z Wang, ... Nature genetics 10 (2), 188-195, 1995 | 728 | 1995 |
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45 Q Zhan, MJ Antinore, XW Wang, F Carrier, ML Smith, CC Harris, ... Oncogene 18 (18), 2892-2900, 1999 | 693 | 1999 |
Identification of microRNA‐181 by genome‐wide screening as a critical player in EpCAM–positive hepatic cancer stem cells J Ji, T Yamashita, A Budhu, M Forgues, HL Jia, C Li, C Deng, E Wauthier, ... Hepatology 50 (2), 472-480, 2009 | 660 | 2009 |
Cancer stem cells in the development of liver cancer T Yamashita, XW Wang The Journal of clinical investigation 123 (5), 1911-1918, 2013 | 605 | 2013 |
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity HS Kim, A Vassilopoulos, RH Wang, T Lahusen, Z Xiao, X Xu, C Li, ... Cancer cell 20 (4), 487-499, 2011 | 601 | 2011 |
Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. K Forrester, S Ambs, SE Lupold, RB Kapust, EA Spillare, WC Weinberg, ... Proceedings of the National Academy of Sciences 93 (6), 2442-2447, 1996 | 569 | 1996 |
Activation of hepatic stem cell marker EpCAM by Wnt–β-catenin signaling in hepatocellular carcinoma T Yamashita, A Budhu, M Forgues, XW Wang Cancer research 67 (22), 10831-10839, 2007 | 557 | 2007 |