| Membrane transporters in drug development KM Giacomini, SM Huang, DJ Tweedie, LZ Benet, KLR Brouwer, X Chu, ... Nature reviews Drug discovery 9 (3), 215, 2010 | 2690 | 2010 |
| Biomarkers of free radical damage: applications in experimental animals and in humans LL de Zwart, JHN Meerman, JNM Commandeur, NPE Vermeulen Free Radical Biology and Medicine 26 (1-2), 202-226, 1999 | 1190 | 1999 |
| Enzyme-catalyzed activation of anticancer prodrugs M Rooseboom, JNM Commandeur, NPE Vermeulen Pharmacological reviews 56 (1), 53-102, 2004 | 574 | 2004 |
| Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics JNM Commandeur Pharmacol Rev. 47, 271-330, 1995 | 410 | 1995 |
| Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic … LW Wormhoudt, JNM Commandeur, NPE Vermeulen Critical reviews in toxicology 29 (1), 59-124, 1999 | 398 | 1999 |
| Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver S Oetari, M Sudibyo, JNM Commandeur, R Samhoedi, NPE Vermeulen Biochemical pharmacology 51 (1), 39-45, 1996 | 281 | 1996 |
| A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies SC Ramaiahgari, MW Den Braver, B Herpers, V Terpstra, ... Archives of toxicology 88 (5), 1083-1095, 2014 | 260 | 2014 |
| Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products R Appiah-Opong, JNM Commandeur, B van Vugt-Lussenburg, ... Toxicology 235 (1-2), 83-91, 2007 | 166 | 2007 |
| Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway AR Goeptar, JNM Commandeur, B van Ommen, PJ van Bladeren, ... Chemical research in toxicology 8 (1), 3-21, 1995 | 139 | 1995 |
| Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of β … I Andreadou, WMPB Menge, JNM Commandeur, EA Worthington, ... Journal of medicinal chemistry 39 (10), 2040-2046, 1996 | 135 | 1996 |
| Identification of critical residues in novel drug metabolizing mutants of cytochrome P450 BM3 using random mutagenesis BMA van Vugt-Lussenburg, E Stjernschantz, J Lastdrager, C Oostenbrink, ... Journal of medicinal chemistry 50 (3), 455-461, 2007 | 129 | 2007 |
| Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities J Venhorst, AM ter Laak, JNM Commandeur, Y Funae, T Hiroi, ... Journal of medicinal chemistry 46 (1), 74-86, 2003 | 119 | 2003 |
| Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites MC Damsten, BMA van Vugt-Lussenburg, T Zeldenthuis, JSB de Vlieger, ... Chemico-biological interactions 171 (1), 96-107, 2008 | 117 | 2008 |
| Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review JNM Commandeur, NPE Vermeulen Chemical research in toxicology 3 (3), 171-194, 1990 | 103 | 1990 |
| Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3 BMA van Vugt-Lussenburg, MC Damsten, DM Maasdijk, NPE Vermeulen, ... Biochemical and biophysical research communications 346 (3), 810-818, 2006 | 101 | 2006 |
| Cytotoxicity and cytoprotective activities of natural compounds. The case of curcumin JNM Commandeur, NPE Vermeulen Xenobiotica 26 (7), 667-680, 1996 | 99 | 1996 |
| Diclofenac inhibits tumor necrosis factor‐α‐induced nuclear factor‐κB activation causing synergistic hepatocyte apoptosis L Fredriksson, B Herpers, G Benedetti, Q Matadin, JC Puigvert, H de Bont, ... Hepatology 53 (6), 2027-2041, 2011 | 89 | 2011 |
| Role of Human Glutathione S-Transferases in the Inactivation of Reactive Metabolites of Clozapine S Dragovic, JS Boerma, L van Bergen, NPE Vermeulen, ... Chemical research in toxicology 23 (9), 1467-1476, 2010 | 77 | 2010 |
| Evaluation of alkoxyresorufins as fluorescent substrates for cytochrome P450 BM3 and site-directed mutants BMA Lussenburg, LC Babel, NPE Vermeulen, JNM Commandeur Analytical biochemistry 341 (1), 148-155, 2005 | 77 | 2005 |
| Liquid chromatography/tandem mass spectrometry detection of covalent binding of acetaminophen to human serum albumin MC Damsten, JNM Commandeur, A Fidder, AG Hulst, D Touw, D Noort, ... Drug metabolism and disposition 35 (8), 1408-1417, 2007 | 76 | 2007 |
