JNM Commandeur
JNM Commandeur
Unknown affiliation
Verified email at vu.nl
Cited by
Cited by
Membrane transporters in drug development
KM Giacomini, SM Huang, DJ Tweedie, LZ Benet, KLR Brouwer, X Chu, ...
Nature reviews Drug discovery 9 (3), 215, 2010
Biomarkers of free radical damage: applications in experimental animals and in humans
LL de Zwart, JHN Meerman, JNM Commandeur, NPE Vermeulen
Free Radical Biology and Medicine 26 (1-2), 202-226, 1999
Enzyme-catalyzed activation of anticancer prodrugs
M Rooseboom, JNM Commandeur, NPE Vermeulen
Pharmacological reviews 56 (1), 53-102, 2004
Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics
JNM Commandeur
Pharmacol Rev. 47, 271-330, 1995
Genetic Polymorphisms of Human N-Acetyltransferase, Cytochrome P450, Glutathione-S-Transferase, and Epoxide Hydrolase Enzymes: Relevance to Xenobiotic …
LW Wormhoudt, JNM Commandeur, NPE Vermeulen
Critical reviews in toxicology 29 (1), 59-124, 1999
Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver
S Oetari, M Sudibyo, JNM Commandeur, R Samhoedi, NPE Vermeulen
Biochemical pharmacology 51 (1), 39-45, 1996
A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies
SC Ramaiahgari, MW Den Braver, B Herpers, V Terpstra, ...
Archives of toxicology 88 (5), 1083-1095, 2014
Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products
R Appiah-Opong, JNM Commandeur, B van Vugt-Lussenburg, ...
Toxicology 235 (1-2), 83-91, 2007
Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway
AR Goeptar, JNM Commandeur, B van Ommen, PJ van Bladeren, ...
Chemical research in toxicology 8 (1), 3-21, 1995
Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of β …
I Andreadou, WMPB Menge, JNM Commandeur, EA Worthington, ...
Journal of medicinal chemistry 39 (10), 2040-2046, 1996
Identification of critical residues in novel drug metabolizing mutants of cytochrome P450 BM3 using random mutagenesis
BMA van Vugt-Lussenburg, E Stjernschantz, J Lastdrager, C Oostenbrink, ...
Journal of medicinal chemistry 50 (3), 455-461, 2007
Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities
J Venhorst, AM ter Laak, JNM Commandeur, Y Funae, T Hiroi, ...
Journal of medicinal chemistry 46 (1), 74-86, 2003
Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites
MC Damsten, BMA van Vugt-Lussenburg, T Zeldenthuis, JSB de Vlieger, ...
Chemico-biological interactions 171 (1), 96-107, 2008
Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review
JNM Commandeur, NPE Vermeulen
Chemical research in toxicology 3 (3), 171-194, 1990
Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3
BMA van Vugt-Lussenburg, MC Damsten, DM Maasdijk, NPE Vermeulen, ...
Biochemical and biophysical research communications 346 (3), 810-818, 2006
Cytotoxicity and cytoprotective activities of natural compounds. The case of curcumin
JNM Commandeur, NPE Vermeulen
Xenobiotica 26 (7), 667-680, 1996
Diclofenac inhibits tumor necrosis factor‐α‐induced nuclear factor‐κB activation causing synergistic hepatocyte apoptosis
L Fredriksson, B Herpers, G Benedetti, Q Matadin, JC Puigvert, H de Bont, ...
Hepatology 53 (6), 2027-2041, 2011
Role of Human Glutathione S-Transferases in the Inactivation of Reactive Metabolites of Clozapine
S Dragovic, JS Boerma, L van Bergen, NPE Vermeulen, ...
Chemical research in toxicology 23 (9), 1467-1476, 2010
Evaluation of alkoxyresorufins as fluorescent substrates for cytochrome P450 BM3 and site-directed mutants
BMA Lussenburg, LC Babel, NPE Vermeulen, JNM Commandeur
Analytical biochemistry 341 (1), 148-155, 2005
Liquid chromatography/tandem mass spectrometry detection of covalent binding of acetaminophen to human serum albumin
MC Damsten, JNM Commandeur, A Fidder, AG Hulst, D Touw, D Noort, ...
Drug metabolism and disposition 35 (8), 1408-1417, 2007
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