Role of Ca2+ in toxic cell killing S Orrenius, DJ McConkey, G Bellomo, P Nicotera
Trends in pharmacological sciences 10 (7), 281-285, 1989
1137 1989 The metabolism of menadione (2-methyl-1, 4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells. H Thor, MT Smith, P Hartzell, G Bellomo, SA Jewell, S Orrenius
Journal of Biological Chemistry 257 (20), 12419-12425, 1982
1076 1982 Free radical-scavenging properties of olive oil polyphenols F Visioli, G Bellomo, C Galli
Biochemical and biophysical research communications 247 (1), 60-64, 1998
990 1998 Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration DJ McConkey, P Nicotera, P Hartzell, G Bellomo, AH Wyllie, S Orrenius
Archives of biochemistry and biophysics 269 (1), 365-370, 1989
708 1989 Bleb formation in hepatocytes during drug metabolism is caused by disturbances in thiol and calcium ion homeostasis SA Jewell, G Bellomo, H Thor, S Orrenius, MT Smith
Science 217 (4566), 1257-1259, 1982
692 1982 Calcium-mediated mechanisms in chemically induced cell death P Nicotera, G Bellomo, S Orrenius
Annual review of pharmacology and toxicology 32 (1), 449-470, 1992
664 1992 Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents F Visioli, G Bellomo, GF Montedoro, C Galli
Atherosclerosis 117 (1), 25-32, 1995
571 1995 Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes D Di Monte, D Ross, G Bellomo, L Eklöw, S Orrenius
Archives of Biochemistry and Biophysics 235 (2), 334-342, 1984
494 1984 Regulation of intracellular calcium compartmentation: studies with isolated hepatocytes and t-butyl hydroperoxide. G Bellomo, SA Jewell, H Thor, S Orrenius
Proceedings of the National Academy of Sciences 79 (22), 6842-6846, 1982
463 1982 Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis D Di Monte, G Bellomo, H Thor, P Nicotera, S Orrenius
Archives of Biochemistry and Biophysics 235 (2), 343-350, 1984
428 1984 HNE interacts directly with JNK isoforms in human hepatic stellate cells. M Parola, G Robino, F Marra, M Pinzani, G Bellomo, G Leonarduzzi, ...
The Journal of clinical investigation 102 (11), 1942-1950, 1998
366 1998 Enhanced LDL oxidation in uremic patients: an additional mechanism for accelerated atherosclerosis? E Maggi, R Bellazzi, F Falaschi, A Frattoni, G Perani, G Finardi, A Gazo, ...
Kidney international 45 (3), 876-883, 1994
351 1994 Measurement of underlying event characteristics using charged particles in pp collisions at and 7 TeV with the ATLAS detector Atlas Collaboration
arXiv preprint arXiv:1012.0791, 2010
341 2010 4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications M Parola, G Bellomo, G Robino, G Barrera, MU Dianzani
Antioxidants & redox signaling 1 (3), 255-284, 1999
333 1999 Altered thiol and calcium homeostasis in oxidative hepatocellular injury G Bellomo, S Orrenius
Hepatology 5 (5), 876-882, 1985
333 1985 When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid M Bagnati, C Perugini, C Cau, R Bordone, E Albano, G Bellomo
Biochemical Journal 340 (1), 143-152, 1999
309 1999 Formation and reduction of glutathione-protein mixed disulfides during oxidative stress: A study with isolated hepatocytes and menadione (2-methyl-1, 4-naphthoquinone) G Bellomo, F Mirabelli, D DiMonte, P Richelmi, H Thor, C Orrenius, ...
Biochemical pharmacology 36 (8), 1313-1320, 1987
309 1987 Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system. P Nicotera, P Hartzell, C Baldi, SA Svensson, G Bellomo, S Orrenius
Journal of Biological Chemistry 261 (31), 14628-14635, 1986
304 1986 Demonstration of nuclear compartmentalization of glutathione in hepatocytes. G Bellomo, M Vairetti, L Stivala, F Mirabelli, P Richelmi, S Orrenius
Proceedings of the National Academy of Sciences 89 (10), 4412-4416, 1992
296 1992 LDL oxidation in patients with severe carotid atherosclerosis. A study of in vitro and in vivo oxidation markers. E Maggi, R Chiesa, G Melissano, R Castellano, D Astore, A Grossi, ...
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology 14 (12), 1892 …, 1994
285 1994