Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair TO Auer, K Duroure, A De Cian, JP Concordet, F Del Bene Genome research 24 (1), 142-153, 2014 | 727 | 2014 |
Targeting telomeres and telomerase A De Cian, L Lacroix, C Douarre, N Temime-Smaali, C Trentesaux, ... Biochimie 90 (1), 131-155, 2008 | 678 | 2008 |
Highly efficient G-quadruplex recognition by bisquinolinium compounds A De Cian, E DeLemos, JL Mergny, MP Teulade-Fichou, D Monchaud Journal of the American Chemical Society 129 (7), 1856-1857, 2007 | 469 | 2007 |
Fluorescence-based melting assays for studying quadruplex ligands A De Cian, L Guittat, M Kaiser, B Saccà, S Amrane, A Bourdoncle, ... Methods 42 (2), 183-195, 2007 | 433 | 2007 |
Kinetics of tetramolecular quadruplexes JL Mergny, A De Cian, A Ghelab, B Sacca, L Lacroix Nucleic acids research 33 (1), 81-94, 2005 | 340 | 2005 |
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action A De Cian, G Cristofari, P Reichenbach, E De Lemos, D Monchaud, ... Proceedings of the National Academy of Sciences 104 (44), 17347-17352, 2007 | 329 | 2007 |
Preferential binding of a G-quadruplex ligand to human chromosome ends C Granotier, G Pennarun, L Riou, F Hoffschir, LR Gauthier, A De Cian, ... Nucleic acids research 33 (13), 4182-4190, 2005 | 322 | 2005 |
Improved genome editing efficiency and flexibility using modified oligonucleotides with TALEN and CRISPR-Cas9 nucleases JB Renaud, C Boix, M Charpentier, A De Cian, J Cochennec, ... Cell reports 14 (9), 2263-2272, 2016 | 316 | 2016 |
Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders D Monchaud, C Allain, H Bertrand, N Smargiasso, F Rosu, V Gabelica, ... Biochimie 90 (8), 1207-1223, 2008 | 294 | 2008 |
CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair M Charpentier, AHY Khedher, S Menoret, A Brion, K Lamribet, E Dardillac, ... Nature communications 9 (1), 1133, 2018 | 217 | 2018 |
Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes J Gros, F Rosu, S Amrane, A De Cian, V Gabelica, L Lacroix, JL Mergny Nucleic acids research 35 (9), 3064-3075, 2007 | 203 | 2007 |
Engineering bisquinolinium/thiazole orange conjugates for fluorescent sensing of G‐quadruplex DNA P Yang, A De Cian, MP Teulade‐Fichou, JL Mergny, D Monchaud Angewandte Chemie 121 (12), 2222-2225, 2009 | 191 | 2009 |
Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy T Larcher, A Lafoux, L Tesson, S Remy, V Thepenier, V François, ... PloS one 9 (10), e110371, 2014 | 174 | 2014 |
Cancer translocations in human cells induced by zinc finger and TALE nucleases M Piganeau, H Ghezraoui, A De Cian, L Guittat, M Tomishima, ... Genome research 23 (7), 1182-1193, 2013 | 172 | 2013 |
The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes H Bertrand, D Monchaud, A De Cian, R Guillot, JL Mergny, ... Organic & biomolecular chemistry 5 (16), 2555-2559, 2007 | 170 | 2007 |
Heritable genome editing with CRISPR/Cas9 induces anosmia in a crop pest moth FA Koutroumpa, C Monsempes, MC François, A de Cian, C Royer, ... Scientific Reports 6 (1), 29620, 2016 | 145 | 2016 |
Sequence effects in single-base loops for quadruplexes A Guédin, A De Cian, J Gros, L Lacroix, JL Mergny Biochimie 90 (5), 686-696, 2008 | 119 | 2008 |
Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype L Weber, G Frati, T Felix, G Hardouin, A Casini, C Wollenschlaeger, ... Science advances 6 (7), eaay9392, 2020 | 117 | 2020 |
A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells B Brassart, D Gomez, A De Cian, R Paterski, A Montagnac, KH Qui, ... Molecular pharmacology 72 (3), 631-640, 2007 | 110 | 2007 |
Ascididemin and meridine stabilise G-quadruplexes and inhibit telomerase in vitro L Guittat, A De Cian, F Rosu, V Gabelica, E De Pauw, E Delfourne, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1724 (3), 375-384, 2005 | 97 | 2005 |