| Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945 N Beckmann, E Giorgetti, A Neuhaus, S Zurbruegg, N Accart, P Smith, ... Acta neuropathologica communications 6, 1-17, 2018 | 112 | 2018 |
| Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders S Carra, P Rusmini, V Crippa, E Giorgetti, A Boncoraglio, R Cristofani, ... Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 100 | 2013 |
| Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins S Carra, V Crippa, P Rusmini, A Boncoraglio, M Minoia, E Giorgetti, ... Progress in neurobiology 97 (2), 83-100, 2012 | 90 | 2012 |
| Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy P Rusmini, V Crippa, E Giorgetti, A Boncoraglio, R Cristofani, S Carra, ... Neurobiology of aging 34 (11), 2585-2603, 2013 | 75 | 2013 |
| Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases R Cristofani, V Crippa, P Rusmini, ME Cicardi, M Meroni, NV Licata, ... Autophagy 13 (8), 1280-1303, 2017 | 73 | 2017 |
| Differential autophagy power in the spinal cord and muscle of transgenic ALS mice V Crippa, A Boncoraglio, M Galbiati, T Aggarwal, P Rusmini, E Giorgetti, ... Frontiers in cellular neuroscience 7, 234, 2013 | 69 | 2013 |
| Aberrant autophagic response in the muscle of a knock-in mouse model of spinal and bulbar muscular atrophy P Rusmini, MJ Polanco, R Cristofani, ME Cicardi, M Meroni, M Galbiati, ... Scientific reports 5 (1), 15174, 2015 | 57 | 2015 |
| Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor B Eftekharzadeh, VC Banduseela, G Chiesa, P Martínez-Cristóbal, ... Nature communications 10 (1), 3562, 2019 | 52 | 2019 |
| Rescue of metabolic alterations in AR113Q skeletal muscle by peripheral androgen receptor gene silencing E Giorgetti, Z Yu, JP Chua, R Shimamura, L Zhao, F Zhu, S Venneti, ... Cell reports 17 (1), 125-136, 2016 | 50 | 2016 |
| Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor–mediated disease JP Chua, SL Reddy, Z Yu, E Giorgetti, HL Montie, S Mukherjee, J Higgins, ... The Journal of Clinical Investigation 125 (2), 831-845, 2015 | 48 | 2015 |
| Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space SM Cadena, Y Zhang, J Fang, S Brachat, P Kuss, E Giorgetti, LS Stodieck, ... Scientific reports 9 (1), 9397, 2019 | 47 | 2019 |
| Synergic prodegradative activity of Bicalutamide and trehalose on the mutant androgen receptor responsible for spinal and bulbar muscular atrophy E Giorgetti, P Rusmini, V Crippa, R Cristofani, A Boncoraglio, ME Cicardi, ... Human molecular genetics 24 (1), 64-75, 2015 | 47 | 2015 |
| Modulation of microglia by voluntary exercise or CSF1R inhibition prevents age-related loss of functional motor units E Giorgetti, M Panesar, Y Zhang, S Joller, M Ronco, M Obrecht, ... Cell reports 29 (6), 1539-1554. e7, 2019 | 46 | 2019 |
| ALS-related misfolded protein management in motor neurons and muscle cells M Galbiati, V Crippa, P Rusmini, R Cristofani, ME Cicardi, E Giorgetti, ... Neurochemistry International 79, 70-78, 2014 | 37 | 2014 |
| Polyglutamine androgen receptor-mediated neuromuscular disease E Giorgetti, AP Lieberman Cellular and molecular life sciences 73, 3991-3999, 2016 | 31 | 2016 |
| Motoneuronal and muscle-selective removal of ALS-related misfolded proteins V Crippa, M Galbiati, A Boncoraglio, P Rusmini, E Onesto, E Giorgetti, ... Biochemical Society Transactions 41 (6), 1598-1604, 2013 | 30 | 2013 |
| Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy M Dossena, G Bedini, P Rusmini, E Giorgetti, A Canazza, V Tosetti, ... PloS one 9 (11), e112746, 2014 | 21 | 2014 |
| Magnetic resonance imaging as a biomarker in rodent peripheral nerve injury models reveals an age-related impairment of nerve regeneration E Giorgetti, M Obrecht, M Ronco, M Panesar, C Lambert, N Accart, ... Scientific Reports 9 (1), 13508, 2019 | 19 | 2019 |
| 994P Efficacy and safety of capmatinib plus spartalizumab in treatment-naïve patients with advanced NSCLC harboring MET exon 14 skipping mutation J Wolf, R Heist, TM Kim, M Nishio, C Dooms, RR Kanthala, E Leo, ... Annals of Oncology 33, S1007-S1008, 2022 | 5 | 2022 |
| First-in-human study of naporafenib (LXH254) with or without spartalizumab in adult patients with advanced solid tumors harboring MAPK signaling pathway alterations F Janku, TM Kim, G Iyer, A Spreafico, E Elez, M de Jonge, N Yamamoto, ... European Journal of Cancer 196, 113458, 2024 | 2 | 2024 |
