| Protein phase separation: a new phase in cell biology S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ... Trends in cell biology 28 (6), 420-435, 2018 | 1818 | 2018 |
| Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ... Nature neuroscience 18 (9), 1226-1229, 2015 | 668 | 2015 |
| Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ... Molecular cell 65 (6), 1044-1055. e5, 2017 | 533 | 2017 |
| Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ... Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019 | 414 | 2019 |
| Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD S Boeynaems*, E Bogaert*, E Michiels, I Gijselinck, A Sieben, A Jovičić, ... Scientific reports 6, 2016 | 294 | 2016 |
| Beyond junk-variable tandem repeats as facilitators of rapid evolution of regulatory and coding sequences R Gemayel, J Cho, S Boeynaems, KJ Verstrepen Genes 3 (3), 461-480, 2012 | 182 | 2012 |
| A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation Y Dorone*, S Boeynaems*, E Flores, B Jin, S Hateley, F Bossi, E Lazarus, ... Cell, 2021 | 163 | 2021 |
| A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism B Swinnen, A Bento-Abreu, TF Gendron, S Boeynaems, E Bogaert, ... Acta neuropathologica 135, 427-443, 2018 | 148 | 2018 |
| Inside out: the role of nucleocytoplasmic transport in ALS and FTLD S Boeynaems, E Bogaert, P Van Damme, L Van Den Bosch Acta neuropathologica 132, 159-173, 2016 | 142 | 2016 |
| Variable glutamine-rich repeats modulate transcription factor activity R Gemayel, S Chavali, K Pougach, M Legendre, B Zhu, S Boeynaems, ... Molecular cell 59 (4), 615-627, 2015 | 134 | 2015 |
| The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems K Lasker, S Boeynaems, V Lam, D Scholl, E Stainton, A Briner, ... Nature Communications 13 (1), 5643, 2022 | 86* | 2022 |
| Molecular dissection of FUS points at synergistic effect of low-complexity domains in toxicity E Bogaert*, S Boeynaems*, M Kato, L Guo, TR Caulfield, J Steyaert, ... Cell reports 24 (3), 529-537. e4, 2018 | 85 | 2018 |
| C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility L Fumagalli*, FL Young*, S Boeynaems*, M De Decker, AR Mehta, ... Science Advances 7 (15), eabg3013, 2021 | 81 | 2021 |
| HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations R Fazal, S Boeynaems, A Swijsen, M De Decker, L Fumagalli, M Moisse, ... The EMBO journal 40 (7), e106177, 2021 | 79 | 2021 |
| Dynamic mapping of proteome trafficking within and between living cells by TransitID W Qin, JS Cheah, C Xu, J Messing, BD Freibaum, S Boeynaems, ... Cell 186 (15), 3307-3324.e30, 2023 | 63 | 2023 |
| C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport J Vanneste, T Vercruysse, S Boeynaems, A Sicart, P Van Damme, ... Scientific reports 9 (1), 15728, 2019 | 62 | 2019 |
| ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization GHP Tazelaar*, S Boeynaems*, M De Decker*, JJFA van Vugt, L Kool, ... Brain communications 2 (2), fcaa064, 2020 | 58 | 2020 |
| Designer condensates: a toolkit for the biomolecular architect RL Hastings, S Boeynaems Journal of Molecular Biology 433 (12), 166837, 2021 | 41 | 2021 |
| Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity LM Gittings, S Boeynaems, D Lightwood, A Clargo, S Topia, L Nakayama, ... Acta neuropathologica 139, 407-410, 2020 | 41 | 2020 |
| Phase separation in biology and disease; current perspectives and open questions S Boeynaems, S Chong, J Gsponer, L Holt, D Milovanovic, DM Mitrea, ... Journal of molecular biology 435 (5), 167971, 2023 | 40 | 2023 |
Ludo Van Den BoschKU Leuven & VIBVerified email at kuleuven.vib.be
