Steven Boeynaems
Steven Boeynaems
Verified email at stanford.edu - Homepage
Title
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Cited by
Year
Protein phase separation: a new phase in cell biology
S Boeynaems, S Alberti, NL Fawzi, T Mittag, M Polymenidou, F Rousseau, ...
Trends in cell biology 28 (6), 420-435, 2018
6602018
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ...
Nature neuroscience 18 (9), 1226-1229, 2015
4392015
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
2872017
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
S Boeynaems, E Bogaert, E Michiels, I Gijselinck, A Sieben, A Jovičić, ...
Scientific reports 6, 2016
1902016
Spontaneous driving forces give rise to protein− RNA condensates with coexisting phases and complex material properties
S Boeynaems, AS Holehouse, V Weinhardt, D Kovacs, J Van Lindt, ...
Proceedings of the National Academy of Sciences 116 (16), 7889-7898, 2019
1292019
Beyond junk-variable tandem repeats as facilitators of rapid evolution of regulatory and coding sequences
R Gemayel, J Cho, S Boeynaems, KJ Verstrepen
Genes 3 (3), 461-480, 2012
1152012
Variable glutamine-rich repeats modulate transcription factor activity
R Gemayel, S Chavali, K Pougach, M Legendre, B Zhu, S Boeynaems, ...
Molecular cell 59 (4), 615-627, 2015
872015
Inside out: the role of nucleocytoplasmic transport in ALS and FTLD
S Boeynaems, E Bogaert, P Van Damme, L Van Den Bosch
Acta neuropathologica 132 (2), 159-173, 2016
852016
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism
B Swinnen, A Bento-Abreu, TF Gendron, S Boeynaems, E Bogaert, ...
Acta neuropathologica 135 (3), 427-443, 2018
712018
Molecular dissection of FUS points at synergistic effect of low-complexity domains in toxicity
E Bogaert, S Boeynaems, M Kato, L Guo, TR Caulfield, J Steyaert, ...
Cell reports 24 (3), 529-537. e4, 2018
372018
C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport
J Vanneste, T Vercruysse, S Boeynaems, A Sicart, P Van Damme, ...
Scientific reports 9 (1), 1-10, 2019
212019
Phasing in on the cell cycle
S Boeynaems, P Tompa, L Van Den Bosch
Cell division 13 (1), 1-8, 2018
192018
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity
LM Gittings, S Boeynaems, D Lightwood, A Clargo, S Topia, L Nakayama, ...
Acta neuropathologica 139 (2), 407-410, 2020
142020
Arginine-rich Peptides Can Actively Mediate Liquid-liquid Phase Separation
S Boeynaems, M De Decker, P Tompa, L Van Den Bosch
Bio-protocol 7 (17), 2017
122017
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility
L Fumagalli, FL Young, S Boeynaems, M De Decker, AR Mehta, ...
Science Advances 7 (15), eabg3013, 2021
92021
ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization
GHP Tazelaar, S Boeynaems, M De Decker, JJFA van Vugt, L Kool, ...
Brain communications 2 (2), fcaa064, 2020
92020
Pour some sugar on TDP (-43)
S Boeynaems, AD Gitler
Molecular cell 71 (5), 649-651, 2018
52018
Hydration-dependent phase separation of a prion-like protein regulates seed germination during water stress
Y Dorone, S Boeynaems, B Jin, F Bossi, E Flores, E Lazarus, E Michiels, ...
Available at SSRN 3680875, 2020
42020
Phosphorylation leads the way for protein aggregate disassembly
S Boeynaems, AD Gitler
Developmental cell 45 (3), 279-281, 2018
22018
HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations
R Fazal, S Boeynaems, A Swijsen, M De Decker, L Fumagalli, M Moisse, ...
The EMBO journal 40 (7), e106177, 2021
12021
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Articles 1–20