Gerhard F Ecker
Gerhard F Ecker
Professor of Pharmacoinformatics, University of Vienna
Verified email at - Homepage
TitleCited byYear
Coexistence of passive and carrier-mediated processes in drug transport
K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ...
Nature reviews Drug discovery 9 (8), 597-614, 2010
Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure–activity relationship
M Murias, N Handler, T Erker, K Pleban, G Ecker, P Saiko, T Szekeres, ...
Bioorganic & medicinal chemistry 12 (21), 5571-5578, 2004
Open PHACTS: semantic interoperability for drug discovery
AJ Williams, L Harland, P Groth, S Pettifer, C Chichester, EL Willighagen, ...
Drug discovery today 17 (21-22), 1188-1198, 2012
On the relationship between feature selection and classification accuracy
A Janecek, W Gansterer, M Demel, G Ecker
New challenges for feature selection in data mining and knowledge discovery …, 2008
Resonances in the weak chiral Lagrangian
G Ecker, J Kambor, D Wyler
Nucl. Phys. B 394 (TUM-T-31-92-27), 101-138, 1992
The importance of a nitrogen atom in modulators of multidrug resistance
G Ecker, M Huber, D Schmid, P Chiba
Molecular pharmacology 56 (4), 791-796, 1999
Low-energy expansion of the pion-nucleon Lagrangian
G Ecker, M Mojzis
arXiv preprint hep-ph/9508204, 1995
P-glycoprotein substrate binding domains are located at the transmembrane domain/transmembrane domain interfaces: a combined photoaffinity labeling-protein homology modeling …
K Pleban, S Kopp, E Csaszar, M Peer, T Hrebicek, A Rizzi, GF Ecker, ...
Molecular pharmacology 67 (2), 365-374, 2005
Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands
L Richter, C De Graaf, W Sieghart, Z Varagic, M Mörzinger, IJP De Esch, ...
Nature chemical biology 8 (5), 455, 2012
< VAP> Green function in the resonance region
V Cirigliano, G Ecker, M Eidemüller, A Pich, J Portolés
Physics Letters B 596 (1-2), 96-106, 2004
Structural requirements for activity of propafenone-type modulators in P-glycoprotein-mediated multidrug resistance.
P Chiba, G Ecker, D Schmid, J Drach, B Tell, S Goldenberg, V Gekeler
Molecular Pharmacology 49 (6), 1122-1130, 1996
The N terminus of monoamine transporters is a lever required for the action of amphetamines
S Sucic, S Dallinger, B Zdrazil, R Weissensteiner, TN Jørgensen, M Holy, ...
Journal of Biological Chemistry 285 (14), 10924-10938, 2010
Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast
M Schuetzer-Muehlbauer, B Willinger, R Egner, G Ecker, K Kuchler
International journal of antimicrobial agents 22 (3), 291-300, 2003
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of toxicology 91 (11), 3477-3505, 2017
Prediction of drug–ABC-transporter interaction—Recent advances and future challenges
F Montanari, GF Ecker
Advanced drug delivery reviews 86, 17-26, 2015
Substituted 4-acylpyrazoles and 4-acylpyrazolones: synthesis and multidrug resistance-modulating activity
P Chiba, W Holzer, M Landau, G Bechmann, K Lorenz, B Plagens, ...
Journal of medicinal chemistry 41 (21), 4001-4011, 1998
Synthesis and in vitro multidrug resistance modulating activity of a series of dihydrobenzopyrans and tetrahydroquinolines
R Hiessböck, C Wolf, E Richter, M Hitzler, P Chiba, M Kratzel, G Ecker
Journal of medicinal chemistry 42 (11), 1921-1926, 1999
Structure–activity relationship studies of propafenone analogs based on P-glycoprotein ATPase activity measurements
D Schmid, G Ecker, S Kopp, M Hitzler, P Chiba
Biochemical pharmacology 58 (9), 1447-1456, 1999
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
L Di, P Artursson, A Avdeef, GF Ecker, B Faller, H Fischer, JB Houston, ...
Drug discovery today 17 (15-16), 905-912, 2012
Structure− Activity Relationship Studies on Benzofuran Analogs of Propafenone-Type Modulators of Tumor Cell Multidrug Resistance
G Ecker, P Chiba, M Hitzler, D Schmid, K Visser, HP Cordes, J Csöllei, ...
Journal of medicinal chemistry 39 (24), 4767-4774, 1996
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