Genetic dissection of the α-globin super-enhancer in vivo D Hay, JR Hughes, C Babbs, JOJ Davies, BJ Graham, LLP Hanssen, ... Nature genetics 48 (8), 895-903, 2016 | 367 | 2016 |
Multiplexed analysis of chromosome conformation at vastly improved sensitivity JOJ Davies, JM Telenius, SJ McGowan, NA Roberts, S Taylor, DR Higgs, ... Nature methods 13 (1), 74, 2016 | 276 | 2016 |
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains AM Oudelaar, JOJ Davies, LLP Hanssen, JM Telenius, R Schwessinger, ... Nature genetics 50 (12), 1744-1751, 2018 | 177 | 2018 |
DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease DM Jeziorska, RJS Murray, M De Gobbi, R Gaentzsch, D Garrick, H Ayyub, ... Proceedings of the National Academy of Sciences 114 (36), E7526-E7535, 2017 | 175 | 2017 |
Molecular dynamics simulations of the interactions of medicinal plant extracts and drugs with lipid bilayer membranes W Kopeć, J Telenius, H Khandelia The FEBS journal 280 (12), 2785-2805, 2013 | 142 | 2013 |
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation L Godfrey, NT Crump, R Thorne, IJ Lau, E Repapi, D Dimou, AL Smith, ... Nature communications 10 (1), 2803, 2019 | 121 | 2019 |
DeepC: predicting 3D genome folding using megabase-scale transfer learning R Schwessinger, M Gosden, D Downes, RC Brown, AM Oudelaar, ... Nature methods 17 (11), 1118-1124, 2020 | 118 | 2020 |
Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia S Mettananda, CA Fisher, D Hay, M Badat, L Quek, K Clark, P Hublitz, ... Nature communications 8 (1), 424, 2017 | 104 | 2017 |
Reconstruction of the global neural crest gene regulatory network in vivo RM Williams, I Candido-Ferreira, E Repapi, D Gavriouchkina, ... Developmental cell 51 (2), 255-276. e7, 2019 | 102 | 2019 |
Molecular organization of the tear fluid lipid layer P Kulovesi, J Telenius, A Koivuniemi, G Brezesinski, A Rantamäki, ... Biophysical journal 99 (8), 2559-2567, 2010 | 88 | 2010 |
Dynamics of the 4D genome during in vivo lineage specification and differentiation AM Oudelaar, RA Beagrie, M Gosden, S de Ornellas, E Georgiades, ... Nature Communications 11 (1), 2722, 2020 | 86 | 2020 |
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions JM Brown, NA Roberts, B Graham, D Waithe, C Lagerholm, JM Telenius, ... Nature communications 9 (1), 3849, 2018 | 73 | 2018 |
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus AM Oudelaar, CL Harrold, LLP Hanssen, JM Telenius, DR Higgs, ... Nature communications 10 (1), 5412, 2019 | 69 | 2019 |
Lessons from the biophysics of interfaces: lung surfactant and tear fluid AH Rantamäki, J Telenius, A Koivuniemi, I Vattulainen, JM Holopainen Progress in retinal and eye research 30 (3), 204-215, 2011 | 57 | 2011 |
The impact of lipid composition on the stability of the tear fluid lipid layer P Kulovesi, J Telenius, A Koivuniemi, G Brezesinski, I Vattulainen, ... Soft Matter 8 (21), 5826-5834, 2012 | 52 | 2012 |
Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell-and tissue-specific DNase footprints R Schwessinger, MC Suciu, SJ McGowan, J Telenius, S Taylor, DR Higgs, ... Genome research 27 (10), 1730-1742, 2017 | 50 | 2017 |
Structural basis of mechanochemical coupling in a hexameric molecular motor DE Kainov, EJ Mancini, J Telenius, J Lisal, JM Grimes, DH Bamford, ... Journal of biological chemistry 283 (6), 3607-3617, 2008 | 45 | 2008 |
Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo CS Simon, DJ Downes, ME Gosden, J Telenius, DR Higgs, JR Hughes, ... Development 144 (7), 1249-1260, 2017 | 43 | 2017 |
Enhancers predominantly regulate gene expression during differentiation via transcription initiation MSC Larke, R Schwessinger, T Nojima, J Telenius, RA Beagrie, ... Molecular cell 81 (5), 983-997. e7, 2021 | 37 | 2021 |
A dynamic folded hairpin conformation is associated with α-globin activation in erythroid cells AM Chiariello, S Bianco, AM Oudelaar, A Esposito, C Annunziatella, ... Cell Reports 30 (7), 2125-2135. e5, 2020 | 36 | 2020 |