|Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits|
O Peñagarikano, BS Abrahams, EI Herman, KD Winden, A Gdalyahu, ...
Cell 147 (1), 235-246, 2011
|Human-specific transcriptional regulation of CNS development genes by FOXP2|
G Konopka, JM Bomar, K Winden, G Coppola, ZO Jonsson, F Gao, ...
Nature 462 (7270), 213-217, 2009
|Human-specific transcriptional networks in the brain|
G Konopka, T Friedrich, J Davis-Turak, K Winden, MC Oldham, F Gao, ...
Neuron 75 (4), 601-617, 2012
|Abnormal mTOR activation in autism|
KD Winden, D Ebrahimi-Fakhari, M Sahin
Annual review of neuroscience 41, 1-23, 2018
|Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling|
EY Rosen, EM Wexler, R Versano, G Coppola, F Gao, KD Winden, ...
Neuron 71 (6), 1030-1042, 2011
|The organization of the transcriptional network in specific neuronal classes|
KD Winden, MC Oldham, K Mirnics, PJ Ebert, CH Swan, P Levitt, ...
Molecular systems biology 5 (1), 291, 2009
|Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin|
M Sundberg, I Tochitsky, DE Buchholz, K Winden, V Kujala, K Kapur, ...
Molecular psychiatry 23 (11), 2167-2183, 2018
|A systems level, functional genomics analysis of chronic epilepsy|
KD Winden, SL Karsten, A Bragin, LC Kudo, L Gehman, J Ruidera, ...
PloS one 6 (6), e20763, 2011
|Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex|
E Ercan, JM Han, A Di Nardo, K Winden, MJ Han, L Hoyo, A Saffari, ...
Journal of Experimental Medicine 214 (3), 681-697, 2017
|CCDC22: a novel candidate gene for syndromic X-linked intellectual disability|
I Voineagu, L Huang, K Winden, M Lazaro, E Haan, J Nelson, ...
Molecular psychiatry 17 (1), 4-7, 2012
|Biallelic mutations in TSC2 lead to abnormalities associated with cortical tubers in human iPSC-derived neurons|
KD Winden, M Sundberg, C Yang, SMA Wafa, S Dwyer, PF Chen, ...
Journal of Neuroscience 39 (47), 9294-9305, 2019
|Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy|
MH Wertz, K Winden, P Neveu, SY Ng, E Ercan, M Sahin
Human molecular genetics 25 (11), 2168-2181, 2016
|Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein|
SA Sagi, CB Lessard, KD Winden, H Maruyama, JC Koo, S Weggen, ...
Journal of Biological Chemistry 286 (46), 39794-39803, 2011
|Megalencephaly and macrocephaly|
KD Winden, CJ Yuskaitis, A Poduri
Seminars in neurology 35 (03), 277-287, 2015
|Arthritis flares mediated by tissue-resident memory T cells in the joint|
MH Chang, A Levescot, N Nelson-Maney, RB Blaustein, KD Winden, ...
Cell reports 37 (4), 109902, 2021
|16p11. 2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro|
M Sundberg, H Pinson, RS Smith, KD Winden, P Venugopal, DJC Tai, ...
Nature communications 12 (1), 2897, 2021
|Phenotypic screen with TSC-deficient neurons reveals heat-shock machinery as a druggable pathway for mTORC1 and reduced cilia|
A Di Nardo, I Lenoël, KD Winden, A Rühmkorf, ME Modi, L Barrett, ...
Cell reports 31 (12), 107780, 2020
|Stroke in primary hyperoxaluria type I|
NM Rao, A Yallapragada, KD Winden, J Saver, DS Liebeskind
Journal of Neuroimaging 24 (4), 411-413, 2014
|Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile|
K Giannikou, Z Zhu, J Kim, KD Winden, ME Tyburczy, D Marron, JS Parker, ...
Modern Pathology 34 (2), 264-279, 2021
|Molecular alterations in areas generating fast ripples in an animal model of temporal lobe epilepsy|
KD Winden, A Bragin, J Engel, DH Geschwind
Neurobiology of disease 78, 35-44, 2015