Folgen
Kathleen B Yates
Kathleen B Yates
Broad Institute of MIT and Harvard
Bestätigte E-Mail-Adresse bei broadinstitute.org
Titel
Zitiert von
Zitiert von
Jahr
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ...
Nature immunology 20 (3), 326-336, 2019
16552019
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ...
Nature 547 (7664), 413-418, 2017
10912017
The epigenetic landscape of T cell exhaustion
DR Sen, J Kaminski, RA Barnitz, M Kurachi, U Gerdemann, KB Yates, ...
Science 354 (6316), 1165-1169, 2016
9142016
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
6472018
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ...
Nature medicine 16 (10), 1147-1151, 2010
6142010
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
5592019
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
PK Gupta, J Godec, D Wolski, E Adland, K Yates, KE Pauken, C Cosgrove, ...
PLoS pathogens 11 (10), e1005177, 2015
4252015
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
M Kurachi, RA Barnitz, N Yosef, PM Odorizzi, MA DiIorio, ME Lemieux, ...
Nature immunology 15 (4), 373-383, 2014
3692014
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ...
Nature 595 (7866), 309-314, 2021
2552021
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
MW LaFleur, TH Nguyen, MA Coxe, BC Miller, KB Yates, JE Gillis, ...
Nature immunology 20 (10), 1335-1347, 2019
1842019
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans
KB Yates, P Tonnerre, GE Martin, U Gerdemann, R Al Abosy, ...
Nature immunology 22 (8), 1020-1029, 2021
1772021
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
J Dubrot, PP Du, SK Lane-Reticker, EA Kessler, AJ Muscato, A Mehta, ...
Nature Immunology 23 (10), 1495-1506, 2022
1142022
A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system
MW LaFleur, TH Nguyen, MA Coxe, KB Yates, JD Trombley, SA Weiss, ...
Nature Communications 10 (1), 1668, 2019
1122019
The PD-1 pathway regulates development and function of memory CD8+ T cells following respiratory viral infection
KE Pauken, J Godec, PM Odorizzi, KE Brown, KB Yates, SF Ngiow, ...
Cell reports 31 (13), 2020
1012020
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection
P Penaloza-MacMaster, DL Barber, EJ Wherry, NM Provine, JE Teigler, ...
Science 347 (6219), 278-282, 2015
862015
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state
S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ...
Nucleic acids research 45 (16), e148-e148, 2017
802017
Targeting TBK1 to overcome resistance to cancer immunotherapy
Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ...
Nature 615 (7950), 158-167, 2023
792023
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation. Cancer Discov. 2018; 8: 216–233. doi: 10.1158/2159-8290
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
CD-17-0915.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
79
TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response
Z Zeng, CJ Wong, L Yang, N Ouardaoui, D Li, W Zhang, S Gu, Y Zhang, ...
Nucleic acids research 50 (D1), D1391-D1397, 2022
762022
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma
J Dubrot, SK Lane-Reticker, EA Kessler, A Ayer, G Mishra, CH Wolfe, ...
Immunity 54 (3), 571-585. e6, 2021
732021
Das System kann den Vorgang jetzt nicht ausführen. Versuchen Sie es später erneut.
Artikel 1–20