| Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions PY Wen, M Weller, EQ Lee, BM Alexander, JS Barnholtz-Sloan, ... Neuro-oncology 22 (8), 1073-1113, 2020 | 699 | 2020 |
| Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity KM Turner, V Deshpande, D Beyter, T Koga, J Rusert, C Lee, B Li, ... Nature 543 (7643), 122-125, 2017 | 614 | 2017 |
| Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA DA Nathanson, B Gini, J Mottahedeh, K Visnyei, T Koga, G Gomez, ... Science 343 (6166), 72-76, 2014 | 573 | 2014 |
| An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR–dependent pathway D Guo, F Reinitz, M Youssef, C Hong, D Nathanson, D Akhavan, D Kuga, ... Cancer discovery 1 (5), 442-456, 2011 | 445 | 2011 |
| Oncogenic EGFR signaling activates an mTORC2–NF-κB pathway that promotes chemotherapy resistance K Tanaka, I Babic, D Nathanson, D Akhavan, D Guo, B Gini, J Dang, ... Cancer discovery 1 (6), 524-538, 2011 | 332 | 2011 |
| 2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling X Fu, RM Chin, L Vergnes, H Hwang, G Deng, Y Xing, MY Pai, S Li, L Ta, ... Cell metabolism 22 (3), 508-515, 2015 | 240 | 2015 |
| EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer I Babic, ES Anderson, K Tanaka, D Guo, K Masui, B Li, S Zhu, Y Gu, ... Cell metabolism 17 (6), 1000-1008, 2013 | 168 | 2013 |
| De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients D Akhavan, AL Pourzia, AA Nourian, KJ Williams, D Nathanson, I Babic, ... Cancer discovery 3 (5), 534-547, 2013 | 147 | 2013 |
| An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis G Tarcic, SK Boguslavsky, J Wakim, T Kiuchi, A Liu, F Reinitz, ... Current Biology 19 (21), 1788-1798, 2009 | 143 | 2009 |
| Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples K Yoshimoto, J Dang, S Zhu, D Nathanson, T Huang, R Dumont, ... Clinical Cancer Research 14 (2), 488-493, 2008 | 126 | 2008 |
| Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240 TR Fenton, D Nathanson, C Ponte de Albuquerque, D Kuga, A Iwanami, ... Proceedings of the National Academy of Sciences 109 (35), 14164-14169, 2012 | 123 | 2012 |
| Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress WR Austin, AL Armijo, DO Campbell, AS Singh, T Hsieh, D Nathanson, ... Journal of Experimental Medicine 209 (12), 2215-2228, 2012 | 117 | 2012 |
| A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens J Sun, MD Masterman-Smith, NA Graham, J Jiao, J Mottahedeh, DR Laks, ... Cancer research 70 (15), 6128-6138, 2010 | 116 | 2010 |
| PET/CT in oncology: current status and perspectives J Czernin, M Allen-Auerbach, D Nathanson, K Herrmann Current radiology reports 1, 177-190, 2013 | 109 | 2013 |
| Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma AH Lee, L Sun, AY Mochizuki, JG Reynoso, J Orpilla, F Chow, JC Kienzler, ... Nature communications 12 (1), 6938, 2021 | 106 | 2021 |
| Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells M Xue, W Wei, Y Su, J Kim, YS Shin, WX Mai, DA Nathanson, JR Heath Journal of the American Chemical Society 137 (12), 4066-4069, 2015 | 105 | 2015 |
| Brain-mimetic 3D culture platforms allow investigation of cooperative effects of extracellular matrix features on therapeutic resistance in glioblastoma W Xiao, R Zhang, A Sohrabi, A Ehsanipour, S Sun, J Liang, CM Walthers, ... Cancer research 78 (5), 1358-1370, 2018 | 93 | 2018 |
| Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma WX Mai, L Gosa, VW Daniels, L Ta, JE Tsang, B Higgins, WB Gilmore, ... Nature medicine 23 (11), 1342-1351, 2017 | 88 | 2017 |
| Microfluidic imaging cytometry H Tseng, K Kamei, J Sun, PS Mischel, MD Masterman-Smith, ... US Patent App. 12/863,526, 2010 | 67 | 2010 |
| Expression of PD-1 by T cells in malignant glioma patients reflects exhaustion and activation TB Davidson, A Lee, M Hsu, S Sedighim, J Orpilla, J Treger, M Mastall, ... Clinical Cancer Research 25 (6), 1913-1922, 2019 | 64 | 2019 |
