| Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein P Desplats, HJ Lee, EJ Bae, C Patrick, E Rockenstein, L Crews, ... Proceedings of the National Academy of Sciences 106 (31), 13010-13015, 2009 | 1734 | 2009 |
| In vivo demonstration that α-synuclein oligomers are toxic B Winner, R Jappelli, SK Maji, PA Desplats, L Boyer, S Aigner, C Hetzer, ... Proceedings of the National Academy of Sciences 108 (10), 4194-4199, 2011 | 1666 | 2011 |
| Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of α-synucleinopathy L Crews, B Spencer, P Desplats, C Patrick, A Paulino, E Rockenstein, ... PloS one 5 (2), e9313, 2010 | 422 | 2010 |
| Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission EJ Bae, HJ Lee, E Rockenstein, DH Ho, EB Park, NY Yang, P Desplats, ... Journal of Neuroscience 32 (39), 13454-13469, 2012 | 382 | 2012 |
| Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes E Masliah, W Dumaop, D Galasko, P Desplats Epigenetics 8 (10), 1030-1038, 2013 | 361 | 2013 |
| α-Synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases P Desplats, B Spencer, E Coffee, P Patel, S Michael, C Patrick, A Adame, ... Journal of Biological Chemistry 286 (11), 9031-9037, 2011 | 338 | 2011 |
| The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice EA Thomas, G Coppola, PA Desplats, B Tang, E Soragni, R Burnett, ... Proceedings of the National Academy of Sciences 105 (40), 15564-15569, 2008 | 338 | 2008 |
| Cell-to-cell transmission of non-prion protein aggregates SJ Lee, P Desplats, C Sigurdson, I Tsigelny, E Masliah Nature Reviews Neurology 6 (12), 702-706, 2010 | 330 | 2010 |
| Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases IF Tsigelny, L Crews, P Desplats, GM Shaked, Y Sharikov, H Mizuno, ... PloS one 3 (9), e3135, 2008 | 329 | 2008 |
| Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation IF Tsigelny, Y Sharikov, W Wrasidlo, T Gonzalez, PA Desplats, L Crews, ... The FEBS journal 279 (6), 1000-1013, 2012 | 208 | 2012 |
| Molecular and pathologic insights from latent HIV-1 infection in the human brain P Desplats, W Dumaop, D Smith, A Adame, I Everall, S Letendre, R Ellis, ... Neurology 80 (15), 1415-1423, 2013 | 193 | 2013 |
| Perfect timing: circadian rhythms, sleep, and immunity—an NIH workshop summary JA Haspel, R Anafi, MK Brown, N Cermakian, C Depner, P Desplats, ... JCI insight 5 (1), 2020 | 184 | 2020 |
| Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model B Winner, P Desplats, C Hagl, J Klucken, R Aigner, S Ploetz, J Laemke, ... Experimental neurology 219 (2), 543-552, 2009 | 181 | 2009 |
| TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson’s disease A Bender, P Desplats, B Spencer, E Rockenstein, A Adame, M Elstner, ... PloS one 8 (4), e62277, 2013 | 179 | 2013 |
| Selective deficits in the expression of striatal‐enriched mRNAs in Huntington's disease PA Desplats, KE Kass, T Gilmartin, GD Stanwood, EL Woodward, ... Journal of neurochemistry 96 (3), 743-757, 2006 | 169 | 2006 |
| α-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice L Crews, H Mizuno, P Desplats, E Rockenstein, A Adame, C Patrick, ... Journal of Neuroscience 28 (16), 4250-4260, 2008 | 154 | 2008 |
| Glycolipid and ganglioside metabolism imbalances in Huntington's disease PA Desplats, CA Denny, KE Kass, T Gilmartin, SR Head, JG Sutcliffe, ... Neurobiology of disease 27 (3), 265-277, 2007 | 154 | 2007 |
| Chemotaxis of Silicibacter sp. Strain TM1040 toward Dinoflagellate Products TR Miller, K Hnilicka, A Dziedzic, P Desplats, R Belas Applied and environmental microbiology 70 (8), 4692-4701, 2004 | 152 | 2004 |
| A de novo compound targeting α-synuclein improves deficits in models of Parkinson’s disease W Wrasidlo, IF Tsigelny, DL Price, G Dutta, E Rockenstein, TC Schwarz, ... Brain 139 (12), 3217-3236, 2016 | 147 | 2016 |
| Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1 P Cronin, MJ McCarthy, ASP Lim, DP Salmon, D Galasko, E Masliah, ... Alzheimer's & Dementia 13 (6), 689-700, 2017 | 106 | 2017 |
