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John Alan Brazier
John Alan Brazier
Associate Professor in Pharmaceutical Chemistry, University of Reading
Bestätigte E-Mail-Adresse bei reading.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity
SE Lee, A Sidorov, T Gourlain, N Mignet, SJ Thorpe, JA Brazier, ...
Nucleic Acids Research 29 (7), 1565-1573, 2001
1722001
I-motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes
JA Brazier, A Shah, GD Brown
Chemical communications 48 (87), 10739-10741, 2012
1332012
Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase
S Takahashi, JA Brazier, N Sugimoto
Proceedings of the National Academy of Sciences 114 (36), 9605-9610, 2017
1212017
The importance of loop length on the stability of i-motif structures
SP Gurung, C Schwarz, JP Hall, CJ Cardin, JA Brazier
Chemical communications 51 (26), 5630-5632, 2015
1152015
X-ray Crystal Structure of rac-[Ru(phen)2dppz]2+ with d(ATGCAT)2 Shows Enantiomer Orientations and Water Ordering
JP Hall, D Cook, SR Morte, P McIntyre, K Buchner, H Beer, DJ Cardin, ...
Journal of the American Chemical Society 135 (34), 12652-12659, 2013
942013
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy
JP Hall, FE Poynton, PM Keane, SP Gurung, JA Brazier, DJ Cardin, ...
Nature Chemistry 7 (12), 961-967, 2015
692015
Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation
JA Brazier, T Shibata, J Townsley, BF Taylor, E Frary, NH Williams, ...
Nucleic acids research 33 (4), 1362-1371, 2005
672005
Structural Studies Reveal Enantiospecific Recognition of a DNA G‐Quadruplex by a Ruthenium Polypyridyl Complex
K McQuaid, H Abell, SP Gurung, DR Allan, G Winter, T Sorensen, ...
Angewandte Chemie International Edition 58 (29), 9881-9885, 2019
432019
Delta chirality ruthenium ‘light-switch’complexes can bind in the minor groove of DNA with five different binding modes
JP Hall, PM Keane, H Beer, K Buchner, G Winter, TL Sorensen, DJ Cardin, ...
Nucleic Acids Research 44 (19), 9472-9482, 2016
422016
Stabilization of the DNA I‐Motif Structure by Incorporation of 3′‐S‐Phosphorothiolate Linkages
JA Brazier, J Fisher, R Cosstick
Angewandte Chemie 118 (1), 120-123, 2006
382006
Controlled dehydration of a ruthenium complex–DNA crystal induces reversible DNA kinking
JP Hall, J Sanchez-Weatherby, C Alberti, CH Quimper, K O’Sullivan, ...
Journal of the American Chemical Society 136 (50), 17505-17512, 2014
272014
Mechanism of the Escherichia coli DNA T: G-mismatch endonuclease (Vsr protein) probed with thiophosphate-containing oligodeoxynucleotides
SL Elliott, J Brazier, R Cosstick, BA Connolly
Journal of molecular biology 353 (3), 692-703, 2005
232005
Guanine can direct binding specificity of Ru–dipyridophenazine (Dppz) complexes to DNA through steric effects
JP Hall, SP Gurung, J Henle, P Poidl, J Andersson, P Lincoln, G Winter, ...
Chemistry–A European Journal 23 (21), 4981-4985, 2017
212017
Long‐Lived Excited‐State Dynamics of i‐Motif Structures Probed by Time‐Resolved Infrared Spectroscopy
PM Keane, FR Baptista, SP Gurung, SJ Devereux, IV Sazanovich, ...
ChemPhysChem 17 (9), 1281-1287, 2016
202016
Duplex stability of DNA· DNA and DNA· RNA duplexes containing 3′-S-phosphorothiolate linkages
J Bentley, JA Brazier, J Fisher, R Cosstick
Organic & Biomolecular Chemistry 5 (22), 3698-3702, 2007
202007
X‐ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru‐dppz Complexes
K McQuaid, JP Hall, JA Brazier, DJ Cardin, CJ Cardin
Chemistry–A European Journal 24 (59), 15859-15867, 2018
172018
Stabilization of the i-motif structure by the intra-strand cross-link formation
K Kikuta, H Piao, J Brazier, Y Taniguchi, K Onizuka, F Nagatsugi, ...
Bioorganic & Medicinal Chemistry Letters 25 (16), 3307-3310, 2015
152015
Stabilization of long-looped i-motif DNA by polypyridyl ruthenium complexes
BJ Pages, SP Gurung, K McQuaid, JP Hall, CJ Cardin, JA Brazier
Frontiers in Chemistry 7, 744, 2019
142019
Synthesis of 3′-S-phosphorothiolate oligonucleotides for their potential use in RNA interference
JW Gaynor, J Brazier, R Cosstick
Nucleosides, Nucleotides, and Nucleic Acids 26 (6-7), 709-712, 2007
132007
Incorporation of a S-glycosidic linkage into a glyconucleoside changes the conformational preference of both furanose sugars
J Buckingham, JA Brazier, J Fisher, R Cosstick
Carbohydrate research 342 (1), 16-22, 2007
132007
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