| Phosphatidylinositol-3-OH kinase direct target of Ras P Rodriguez-Viciana, PH Warne, R Dhand, B Vanhaesebroeck, I Gout, ... Nature 370 (6490), 527-532, 1994 | 2672 | 1994 |
| Suppression of c-Myc-induced apoptosis by Ras signalling through PI (3) K and PKB A Kauffmann-Zeh, P Rodriguez-Viciana, E Ulrich, C Gilbert, P Coffer, ... Nature 385 (6616), 544-548, 1997 | 1500 | 1997 |
| Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras P Rodriguez-Viciana, PH Warne, A Khwaja, BM Marte, D Pappin, P Das, ... Cell 89 (3), 457-467, 1997 | 1357 | 1997 |
| Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway A Khwaja, P Rodriguez‐Viciana, S Wennström, PH Warne, J Downward The EMBO journal, 1997 | 1303 | 1997 |
| Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro PH Warne, PR Vician, J Downward Nature 364 (6435), 352-355, 1993 | 959 | 1993 |
| Activation of phosphoinositide 3‐kinase by interaction with Ras and by point mutation. P Rodriguez‐Viciana, PH Warne, B Vanhaesebroeck, MD Waterfield, ... The EMBO journal 15 (10), 2442-2451, 1996 | 786 | 1996 |
| Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome P Rodriguez-Viciana, O Tetsu, WE Tidyman, AL Estep, BA Conger, ... Science 311 (5765), 1287-1290, 2006 | 622 | 2006 |
| The activation of phosphatidylinositol 3-kinase by Ras T Kodaki, R Woscholski, B Hallberg, PRVJ Downward, PJ Parker Current biology 4 (9), 798-806, 1994 | 485 | 1994 |
| Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate P Rodriguez-Viciana, C Sabatier, F McCormick Molecular and cellular biology 24 (11), 4943-4954, 2004 | 383 | 2004 |
| Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase C Jimenez, DR Jones, P Rodríguez‐Viciana, A Gonzalez‐García, ... The EMBO journal, 1998 | 333 | 1998 |
| A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells. L Buday, SE Egan, PR Viciana, DA Cantrell, J Downward Journal of Biological Chemistry 269 (12), 9019-9023, 1994 | 329 | 1994 |
| R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways BM Marte, P Rodriguez-Viciana, S Wennström, PH Warne, J Downward Current Biology 7 (1), 63-71, 1997 | 306 | 1997 |
| A conditional feedback loop regulates Ras activity through EphA2 M Macrae, RM Neve, P Rodriguez-Viciana, C Haqq, J Yeh, C Chen, ... Cancer cell 8 (2), 111-118, 2005 | 302 | 2005 |
| A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity P Rodriguez-Viciana, J Oses-Prieto, A Burlingame, M Fried, F McCormick Molecular cell 22 (2), 217-230, 2006 | 221 | 2006 |
| PIK3CA cooperates with other phosphatidylinositol 3′-kinase pathway mutations to effect oncogenic transformation K Oda, J Okada, L Timmerman, P Rodriguez-Viciana, D Stokoe, K Shoji, ... Cancer research 68 (19), 8127-8136, 2008 | 206 | 2008 |
| Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf–MEK–extracellular signal-regulated kinase pathway SH Hansen, MMP Zegers, M Woodrow, P Rodriguez-Viciana, P Chardin, ... Molecular and cellular biology 20 (24), 9364-9375, 2000 | 137 | 2000 |
| Cancer targets in the Ras pathway P Rodriguez-Viciana, O Tetsu, K Oda, J Okada, K Rauen, F McCormick Cold Spring Harbor symposia on quantitative biology 70, 461-467, 2005 | 131 | 2005 |
| Interaction of Ras with phosphoinositide 3-kinase γ I Rubio, P RODRIGUEZ-VICIANA, J DOWNWARD, R WETZKER Biochemical Journal 326 (3), 891-895, 1997 | 131 | 1997 |
| Phosphatidylinositol 3’kinase: one of the effectors of Ras P Rodriguez-Viciana, BM Marte, PH Warne, J Downward, CJ Marshall Philosophical Transactions of the Royal Society of London. Series B …, 1996 | 123 | 1996 |
| H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of β-catenin in epidermal keratinocytes J Espada, M Pérez-Moreno, VMM Braga, P Rodriguez-Viciana, A Cano The Journal of cell biology 146 (5), 967-980, 1999 | 115 | 1999 |
