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Dennis Svatunek
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Development of a 18F‐Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging
C Denk, D Svatunek, T Filip, T Wanek, D Lumpi, J Fröhlich, C Kuntner, ...
Angewandte Chemie International Edition 53 (36), 9655-9659, 2014
1232014
Design, Synthesis, and Evaluation of a Low-Molecular-Weight 11C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry
C Denk, D Svatunek, S Mairinger, J Stanek, T Filip, D Matscheko, ...
Bioconjugate Chemistry 27 (7), 1707-1712, 2016
872016
Stable, reactive, and orthogonal tetrazines: dispersion forces promote the cycloaddition with isonitriles
J Tu, D Svatunek, S Parvez, AC Liu, BJ Levandowski, HJ Eckvahl, ...
Angewandte Chemie International Edition 58 (27), 9043-9048, 2019
782019
Conformationally Strained trans-Cyclooctene (sTCO) Enables the Rapid Construction of 18 F-PET Probes via Tetrazine Ligation
M Wang, D Svatunek, K Rohlfing, Y Liu, H Wang, B Giglio, H Yuan, Z Wu, ...
752016
Practical and efficient large-scale preparation of dimethyldioxirane
H Mikula, D Svatunek, D Lumpi, F Glöcklhofer, C Hametner, J Fröhlich
Organic Process Research & Development 17 (2), 313-316, 2013
682013
Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging
EJL Stéen, JT Jørgensen, K Johann, K Norregaard, B Sohr, D Svatunek, ...
ACS nano, 2020
622020
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry
EJL Stéen, JT Jørgensen, C Denk, UM Battisti, K Nørregaard, PE Edem, ...
ACS pharmacology & translational science 4 (2), 824-833, 2021
582021
Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions
D Svatunek, N Houszka, TA Hamlin, FM Bickelhaupt, H Mikula
Chemistry–A European Journal 25 (3), 754-758, 2019
532019
Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups
J Tu, D Svatunek, S Parvez, HJ Eckvahl, M Xu, RT Peterson, KN Houk, ...
Chemical science 11 (1), 169-179, 2020
452020
Uncovering the key role of distortion in bioorthogonal tetrazine tools that defy the reactivity/stability trade-off
D Svatunek, M Wilkovitsch, L Hartmann, KN Houk, H Mikula
Journal of the American Chemical Society 144 (18), 8171-8177, 2022
432022
Direct Cu-mediated aromatic 18 F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging
R García-Vázquez, UM Battisti, JT Jørgensen, V Shalgunov, L Hvass, ...
Chemical science 12 (35), 11668-11675, 2021
412021
Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization
D Svatunek, C Denk, V Rosecker, B Sohr, C Hametner, G Allmaier, ...
Monatshefte für Chemie-Chemical Monthly 147, 579-585, 2016
332016
Tetrazine-and trans-cyclooctene-functionalised polypept (o) ides for fast bioorthogonal tetrazine ligation
K Johann, D Svatunek, C Seidl, S Rizzelli, TA Bauer, L Braun, K Koynov, ...
Polymer Chemistry 11 (27), 4396-4407, 2020
322020
autoDIAS: a python tool for an automated distortion/interaction activation strain analysis
D Svatunek, KN Houk
Journal of Computational Chemistry 40 (28), 2509-2515, 2019
312019
Cycloaddition reactivities analyzed by energy decomposition analyses and the frontier molecular orbital model
A Sengupta, B Li, D Svatunek, F Liu, KN Houk
Accounts of Chemical Research 55 (17), 2467-2479, 2022
282022
Factors Controlling the Diels–Alder Reactivity of Hetero‐1, 3‐Butadienes
S Yu, HM de Bruijn, D Svatunek, TA Hamlin, FM Bickelhaupt
ChemistryOpen 7 (12), 995-1004, 2018
282018
Origins of Endo Selectivity in Diels–Alder Reactions of Cyclic Allene Dienophiles
M Ramirez, D Svatunek, F Liu, NK Garg, KN Houk
Angewandte Chemie 133 (27), 15116-15124, 2021
272021
Elucidating the Trends in Reactivity of Aza‐1, 3‐Dipolar Cycloadditions
TA Hamlin, D Svatunek, S Yu, L Ridder, I Infante, L Visscher, ...
European Journal of Organic Chemistry 2019 (2-3), 378-386, 2019
252019
Secondary orbital interactions enhance the reactivity of alkynes in Diels–Alder cycloadditions
BJ Levandowski, D Svatunek, B Sohr, H Mikula, KN Houk
Journal of the American Chemical Society 141 (6), 2224-2227, 2019
242019
How the Lewis Base F Catalyzes the 1,3-Dipolar Cycloaddition between Carbon Dioxide and Nitrilimines
D Svatunek, T Hansen, KN Houk, TA Hamlin
The Journal of organic chemistry 86 (5), 4320-4325, 2021
192021
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