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Dennis Svatunek
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Development of a 18F‐Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging
C Denk, D Svatunek, T Filip, T Wanek, D Lumpi, J Fröhlich, C Kuntner, ...
Angewandte Chemie International Edition 53 (36), 9655-9659, 2014
1012014
Design, Synthesis, and Evaluation of a Low-Molecular-Weight 11C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry
C Denk, D Svatunek, S Mairinger, J Stanek, T Filip, D Matscheko, ...
Bioconjugate Chemistry 27 (7), 1707-1712, 2016
612016
Conformationally Strained trans-Cyclooctene (sTCO) Enables the Rapid Construction of 18 F-PET Probes via Tetrazine Ligation
M Wang, D Svatunek, K Rohlfing, Y Liu, H Wang, B Giglio, H Yuan, Z Wu, ...
552016
Practical and efficient large-scale preparation of dimethyldioxirane
H Mikula, D Svatunek, D Lumpi, F Glöcklhofer, C Hametner, J Fröhlich
Organic Process Research & Development 17 (2), 313-316, 2013
542013
Stable, reactive, and orthogonal tetrazines: Dispersion forces promote the cycloaddition with isonitriles
J Tu, D Svatunek, S Parvez, AC Liu, BJ Levandowski, HJ Eckvahl, ...
Angewandte Chemie International Edition 58 (27), 9043-9048, 2019
482019
Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions
D Svatunek, N Houszka, TA Hamlin, FM Bickelhaupt, H Mikula
Chemistry–A European Journal 25 (3), 754-758, 2019
332019
Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups
J Tu, D Svatunek, S Parvez, HJ Eckvahl, M Xu, RT Peterson, KN Houk, ...
Chemical science 11 (1), 169-179, 2020
302020
Trans-cyclooctene-functionalized PeptoBrushes with improved reaction kinetics of the tetrazine ligation for pretargeted nuclear imaging
EJL Stéen, JT Jørgensen, K Johann, K Norregaard, B Sohr, D Svatunek, ...
ACS nano, 2020
302020
Efficient low-cost preparation of trans-cyclooctenes using a simplified flow setup for photoisomerization
D Svatunek, C Denk, V Rosecker, B Sohr, C Hametner, G Allmaier, ...
Monatshefte für Chemie-Chemical Monthly 147 (3), 579-585, 2016
252016
Factors Controlling the Diels–Alder Reactivity of Hetero‐1, 3‐Butadienes
S Yu, HM de Bruijn, D Svatunek, TA Hamlin, FM Bickelhaupt
ChemistryOpen 7 (12), 995-1004, 2018
212018
Elucidating the Trends in Reactivity of Aza‐1, 3‐Dipolar Cycloadditions
TA Hamlin, D Svatunek, S Yu, L Ridder, I Infante, L Visscher, ...
European Journal of Organic Chemistry 2019 (2-3), 378-386, 2019
182019
Synthesis of zearalenone-16-β, D-glucoside and zearalenone-16-sulfate: A tale of protecting resorcylic acid lactones for regiocontrolled conjugation
H Mikula, J Weber, D Svatunek, P Skrinjar, G Adam, R Krska, C Hametner, ...
Beilstein journal of organic chemistry 10 (1), 1129-1134, 2014
172014
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry
EJL Stéen, JT Jørgensen, C Denk, UM Battisti, K Nørregaard, PE Edem, ...
ACS Pharmacology & Translational Science 4 (2), 824-833, 2021
162021
Tetrazine-and trans-cyclooctene-functionalised polypept (o) ides for fast bioorthogonal tetrazine ligation
K Johann, D Svatunek, C Seidl, S Rizzelli, TA Bauer, L Braun, K Koynov, ...
Polymer Chemistry 11 (27), 4396-4407, 2020
142020
autoDIAS: a python tool for an automated distortion/interaction activation strain analysis
D Svatunek, KN Houk
Journal of Computational Chemistry 40 (28), 2509-2515, 2019
132019
Secondary orbital interactions enhance the reactivity of alkynes in Diels–Alder cycloadditions
BJ Levandowski, D Svatunek, B Sohr, H Mikula, KN Houk
Journal of the American Chemical Society 141 (6), 2224-2227, 2019
122019
[18 F] Fluoroalkyl azides for rapid radiolabeling and (Re) investigation of their potential towards in vivo click chemistry
C Denk, M Wilkovitsch, P Skrinjar, D Svatunek, S Mairinger, C Kuntner, ...
Organic & Biomolecular Chemistry 15 (28), 5976-5982, 2017
122017
HPMA-based nanoparticles for fast, bioorthogonal IEDDA ligation
S Kramer, D Svatunek, I Alberg, B Gräfen, S Schmitt, L Braun, ...
Biomacromolecules 20 (10), 3786-3797, 2019
112019
Entwicklung eines 18F‐markierten Tetrazins mit vorteilhaften pharmakokinetischen Eigenschaften für die bioorthogonale Positronenemissionstomographie
C Denk, D Svatunek, T Filip, T Wanek, D Lumpi, J Fröhlich, C Kuntner, ...
Angewandte Chemie 126 (36), 9810-9814, 2014
112014
Acylation-Mediated ‘Kinetic Turn-On’of 3-Amino-1, 2, 4, 5-tetrazines
S Kronister, D Svatunek, C Denk, H Mikula
Synlett 29 (10), 1297-1302, 2018
102018
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