Daniel Poppe
Daniel Poppe
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Small molecules enable highly efficient neuronal conversion of human fibroblasts
J Ladewig, J Mertens, J Kesavan, J Doerr, D Poppe, F Glaue, S Herms, ...
Nature Methods 9 (6), 575-578, 2012
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
P Koch, P Breuer, M Peitz, J Jungverdorben, J Kesavan, D Poppe, J Doerr, ...
Nature 480 (7378), 543-546, 2011
A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ...
Nature Neuroscience 22 (12), 2087-2097, 2019
Systematic assessment of tissue dissociation and storage biases in single cell and single-nucleus RNA-seq workflows
E Denisenko, BB Guo, M Jones, R Hou, L de Kock, T Lassmann, D Poppe, ...
Genome Biology 21 (130), 1-25, 2020
Modelling human blastocysts by reprogramming fibroblasts into iBlastoids
X Liu, JP Tan, J Schröder, A Aberkane, JF Ouyang, M Mohenska, SM Lim, ...
Nature 591 (7851), 1-6, 2021
Reprogramming roadmap reveals route to human induced trophoblast stem cells
X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ...
Nature 586 (7827), 101-107, 2020
Embryonic Stem Cell–Based Modeling of Tau Pathology in Human Neurons
J Mertens, K Stüber, D Poppe, J Doerr, J Ladewig, O Brüstle, P Koch
The American Journal of Pathology 182 (5), 1769-1779, 2013
The emergence of the brain non-CpG methylation system in vertebrates
A de Mendoza, D Poppe, S Buckberry, J Pflueger, CB Albertin, T Daish, ...
Nature Ecology & Evolution 5 (2), 1-9, 2021
Genome editing in neuroepithelial stem cells to generate human neurons with high adenosine‐releasing capacity
D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, ...
Stem Cells Translational Medicine 7 (6), 477-486, 2018
Conserved and divergent features of DNA methylation in embryonic stem cell-derived neurons
S Martin, D Poppe, N Olova, C O’Leary, E Ivanova, J Pflueger, J Dechka, ...
bioRxiv, 2020
Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential
bioRxiv,, 2022
Comprehensive evaluation of deconvolution methods for human brain gene expression
GJ Sutton, D Poppe, RK Simmons, K Walsh, U Nawaz, R Lister, ...
Nature Communications 13 (1), 1-18, 2022
An environmentally-responsive transcriptional state modulates cell identities during root development
RL Marina Oliva, Tim Stuart, Dave Tang, Jahnvi Pflueger, Daniel Poppe, Jafar ...
bioRxiv, 2022
Single-nucleus RNA sequencing reveals novel molecular signatures of healthy and chronically injured liver
R Carlessi, J Kohn-Gaone, ND Abu Bakar, E Denisenko, M Jones, ...
Journal of Gastroenterology and Hepatology 35 (Suppl. 1), 25-26, 2020
Cell culture-generated neurons show non-physiological DNA methylation signatures
D Poppe, S Martin, J Pflueger, E Wolvetang, R Lister
ISSCR Annual Meeting 2018, 2018
Gene targeting in human pluripotent cell-derived neural stem cells for the study and treatment of neurological disorders
D Poppe
University of Bonn, 2015
Generation of adenosine-kinase-deficient human neuroepthelial stem cells for cell-based delivery of adenosine into the central nervous system.
D Poppe, J Doerr, JA Steinbeck, A Reik, DE Paschon, PD Gregory, ...
Cell Symposia: Using Stem Cells to Model and Treat Human Disease, 2013
Gene correction of an expanded CAG repeat in induced pluripotent stem cell-derived neural stem cells using adeno-associated virus-mediated targeting
D Poppe, P Breuer, J Doerr, J Jungverdorben, M Peitz, O Brüstle, P Koch
Cell Symposia: Using Stem Cells to Model and Treat Human Disease, 2013
Gene-correction in induced pluripotent stem cell derived neural stem cells using AAV-mediated targeting
D Poppe, P Breuer, J Doerr, J Jungverdorben, M Peitz, O Brüstle, P Koch
SfN Neuroscience 2011, 2011
Gene targeting in human embryonic stem cell derived neural precursor cells with adeno-associated viral vectors
D Poppe
University of Bonn, 2008
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