A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ... Nature Neuroscience 22 (12), 2087-2097, 2019 | 766 | 2019 |
Systematic assessment of tissue dissociation and storage biases in single cell and single-nucleus RNA-seq workflows E Denisenko, BB Guo, M Jones, R Hou, L de Kock, T Lassmann, D Poppe, ... Genome Biology 21 (130), 1-25, 2020 | 483 | 2020 |
Small molecules enable highly efficient neuronal conversion of human fibroblasts J Ladewig, J Mertens, J Kesavan, J Doerr, D Poppe, F Glaue, S Herms, ... Nature Methods 9 (6), 575-578, 2012 | 388 | 2012 |
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease P Koch, P Breuer, M Peitz, J Jungverdorben, J Kesavan, D Poppe, J Doerr, ... Nature 480 (7378), 543-546, 2011 | 373 | 2011 |
Modelling human blastocysts by reprogramming fibroblasts into iBlastoids X Liu, JP Tan, J Schröder, A Aberkane, JF Ouyang, M Mohenska, SM Lim, ... Nature 591 (7851), 1-6, 2021 | 308 | 2021 |
Reprogramming roadmap reveals route to human induced trophoblast stem cells X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ... Nature 586 (7827), 101-107, 2020 | 173 | 2020 |
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution CA Herring, RK Simmons, S Freytag, D Poppe, JJD Moffet, J Pflueger, ... Cell 185 (23), 2022 | 104 | 2022 |
The emergence of the brain non-CpG methylation system in vertebrates A de Mendoza, D Poppe, S Buckberry, J Pflueger, CB Albertin, T Daish, ... Nature Ecology & Evolution 5 (2), 1-9, 2021 | 97 | 2021 |
Comprehensive evaluation of deconvolution methods for human brain gene expression GJ Sutton, D Poppe, RK Simmons, K Walsh, U Nawaz, R Lister, ... Nature Communications 13 (1), 1358, 2022 | 85 | 2022 |
Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability A de Mendoza, TV Nguyen, E Ford, D Poppe, S Buckberry, J Pflueger, ... Genome Biology 23, 163, 2022 | 70 | 2022 |
Embryonic Stem Cell–Based Modeling of Tau Pathology in Human Neurons J Mertens, K Stüber, D Poppe, J Doerr, J Ladewig, O Brüstle, P Koch The American Journal of Pathology 182 (5), 1769-1779, 2013 | 46 | 2013 |
Transient naive reprogramming corrects hiPS cells functionally and epigenetically S Buckberry, X Liu, D Poppe, JP Tang, G Sun, J Chen, TV Nguyen, ... Nature 620 (7975), 863-872, 2023 | 35 | 2023 |
Genome editing in neuroepithelial stem cells to generate human neurons with high adenosine‐releasing capacity D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, ... Stem Cells Translational Medicine 7 (6), 477-486, 2018 | 17 | 2018 |
Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential R Carlessi, E Denisenko, E Boslem, J Köhn-Gaone, N Main, ... Cell Genomics 3 (5), 2023.100301, 2023 | 12 | 2023 |
A modular dCas9-based recruitment platform for combinatorial epigenome editing T Swain, C Pflueger, S Freytag, D Poppe, J Pflueger, TV Nguyen, JK Li, ... Nucleic Acid Research 51 (21), 2023 | 11 | 2023 |
An environmentally-responsive transcriptional state modulates cell identities during root development M Oliva, T Stuart, D Tang, J Pflueger, D Poppe, JS Jabbari, S Gigante, ... bioRxiv, 2022 | 9 | 2022 |
Embryonic Stem Cell-Derived Neurons as a Model System for Epigenome Maturation during Development S Martin, D Poppe, N Olova, C O’Leary, E Ivanova, J Pflueger, J Dechka, ... Genes 14 (5), 957, 2023 | 3* | 2023 |
Transient Naive Reprogramming Corrects Human iPS Cells Functionally and Epigenetically D Poppe ISSCR Annual Meeting 2024, 429-430, 2024 | | 2024 |
Transient Naive Treatment (TNT) iPS cells do not feature Sendai virus expression: Response to Sendai virus persistence questions the transient naive reprogramming method for … S Buckberry, X Liu, D Poppe, JP Tan, GJ Faulkner, JM Polo, R Lister bioRxiv, https://doi.org/10.1101/2024.07.10.60280, 2024 | | 2024 |
Improving epigenome maturation in human neurons in vitro D Poppe 1st Epigenetics Society International Meeting, 2023 | | 2023 |