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Sven Marcel Stefan
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107432021
Marilines A–C: Novel Phthalimidines from the Sponge‐Derived Fungus Stachylidium sp.
C Almeida, Y Hemberger, SM Schmitt, S Bouhired, L Natesan, S Kehraus, ...
Chemistry–A European Journal 18 (28), 8827-8834, 2012
752012
Small‐molecule inhibitors of multidrug resistance‐associated protein 1 and related processes: A historic approach and recent advances
SM Stefan, M Wiese
Medicinal Research Reviews 39 (1), 176-264, 2019
672019
9-Deazapurines as broad-spectrum inhibitors of the ABC transport proteins P-glycoprotein, multidrug resistance-associated protein 1, and breast cancer resistance protein
K Stefan, SM Schmitt, M Wiese
Journal of medicinal chemistry 60 (21), 8758-8780, 2017
622017
Multi-target ABC transporter modulators: what next and where to go?
SM Stefan
Future Medicinal Chemistry 11 (18), 2353-2358, 2019
542019
Pyrrolopyrimidine derivatives as novel inhibitors of multidrug resistance-associated protein 1 (MRP1, ABCC1)
SM Schmitt, K Stefan, M Wiese
Journal of medicinal chemistry 59 (7), 3018-3033, 2016
482016
Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2
K Silbermann, CP Shah, NU Sahu, K Juvale, SM Stefan, PS Kharkar, ...
European Journal of Medicinal Chemistry 164, 193-213, 2019
432019
Guidelines for the use and interpretation of assays for monitoring autophagy 1
D Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
Autophagy 17 (1), 1-382, 2021
312021
Identification of thienopyrimidine scaffold as an inhibitor of the ABC transport protein ABCC1 (MRP1) and related transporters using a combined virtual screening approach
K Silbermann, SM Stefan, R Elshawadfy, V Namasivayam, M Wiese
Journal of Medicinal Chemistry 62 (9), 4383-4400, 2019
312019
The A‐B‐C of small‐molecule ABC transport protein modulators: From inhibition to activation—a case study of multidrug resistance‐associated protein 1 (ABCC1)
M Wiese, SM Stefan
Medicinal Research Reviews 39 (6), 2031-2081, 2019
292019
Pyrrolopyrimidine derivatives and purine analogs as novel activators of Multidrug Resistance-associated Protein 1 (MRP1, ABCC1)
SM Schmitt, K Stefan, M Wiese
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (1), 69-79, 2017
262017
Superior pyrimidine derivatives as selective ABCG2 inhibitors and broad-spectrum ABCB1, ABCC1, and ABCG2 antagonists
K Silbermann, J Li, V Namasivayam, F Baltes, G Bendas, SM Stefan, ...
Journal of Medicinal Chemistry 63 (18), 10412-10432, 2020
252020
C@ PA: computer-aided pattern analysis to predict multitarget ABC transporter inhibitors
V Namasivayam, K Silbermann, M Wiese, J Pahnke, SM Stefan
Journal of Medicinal Chemistry 64 (6), 3350-3366, 2021
202021
The growing evidence for targeting P-glycoprotein in lysosomes to overcome resistance
SM Stefan, PJ Jansson, DS Kalinowski, R Anjum, M Dharmasivam, ...
Future Medicinal Chemistry 12 (6), 473-477, 2020
202020
Rational drug design of 6-substituted 4-anilino-2-phenylpyrimidines for exploration of novel ABCG2 binding site
K Silbermann, J Li, V Namasivayam, SM Stefan, M Wiese
European Journal of Medicinal Chemistry 212, 113045, 2021
192021
Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: anchor point for innovative Alzheimer's disease therapeutics
V Namasivayam, K Stefan, L Gorecki, J Korabecny, O Soukup, ...
International Journal of Biological Macromolecules 217, 775-791, 2022
172022
Strategies to gain novel Alzheimer’s disease diagnostics and therapeutics using modulators of ABCA transporters
J Pahnke, P Bascuñana, M Brackhan, K Stefan, V Namasivayam, ...
Free neuropathology 2, 2021
172021
Structural feature-driven pattern analysis for multitarget modulator landscapes
V Namasivayam, K Stefan, K Silbermann, J Pahnke, M Wiese, SM Stefan
Bioinformatics 38 (5), 1385-1392, 2022
152022
Indole derivatives as new structural class of potent and antiproliferative inhibitors of monocarboxylate transporter 1 (MCT1; SLC16A1)
S Puri, K Stefan, SL Khan, J Pahnke, SM Stefan, K Juvale
Journal of Medicinal Chemistry 66 (1), 657-676, 2022
132022
Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics
V Namasivayam, K Stefan, J Pahnke, SM Stefan
Computational and Structural Biotechnology Journal 19, 6490-6504, 2021
132021
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