|Bacterial transcription as a target for antibacterial drug development|
C Ma, X Yang, PJ Lewis
Microbiology and Molecular Biology Reviews 80 (1), 139-160, 2016
|Catalytic Asymmetric C N Bond Formation: Phosphine‐Catalyzed Intra‐and Intermolecular γ‐Addition of Nitrogen Nucleophiles to Allenoates and Alkynoates|
RJ Lundgren, A Wilsily, N Marion, C Ma, YK Chung, GC Fu
Angewandte Chemie International Edition 52 (9), 2525-2528, 2013
|Discovery of novel quinoline–chalcone derivatives as potent antitumor agents with microtubule polymerization inhibitory activity|
W Li, F Xu, W Shuai, H Sun, H Yao, C Ma, S Xu, H Yao, Z Zhu, DH Yang, ...
Journal of medicinal chemistry 62 (2), 993-1013, 2018
|Inhibitors of bacterial transcription initiation complex formation|
C Ma, X Yang, H Kandemir, M Mielczarek, EB Johnston, R Griffith, ...
ACS Chemical Biology 8 (9), 1972-1980, 2013
|Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site|
W Li, W Shuai, H Sun, F Xu, Y Bi, J Xu, C Ma, H Yao, Z Zhu, S Xu
European Journal of Medicinal Chemistry 163, 428-442, 2019
|Synthesis and biological evaluation of novel ocotillol-type triterpenoid derivatives as antibacterial agents|
Z Zhou, C Ma, H Zhang, Y Bi, X Chen, H Tian, X Xie, Q Meng, PJ Lewis, ...
European journal of medicinal chemistry 68, 444-453, 2013
|Ring‐Closing Metathesis in the Synthesis of BC Ring‐Systems of Taxol|
C Ma, S Schiltz, XF Le Goff, J Prunet
Chemistry–A European Journal 14 (24), 7314-7323, 2008
|Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents|
F Xu, W Li, W Shuai, L Yang, Y Bi, C Ma, H Yao, S Xu, Z Zhu, J Xu
European Journal of Medicinal Chemistry 173, 1-14, 2019
|Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives|
Y Bi, X Yang, T Zhang, Z Liu, X Zhang, J Lu, K Cheng, J Xu, H Wang, G Lv, ...
European Journal of Medicinal Chemistry 101, 71-80, 2015
|Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation|
M Mielczarek, RV Devakaram, C Ma, X Yang, H Kandemir, B Purwono, ...
Organic & biomolecular chemistry 12 (18), 2882-2894, 2014
|RNA polymerase-induced remodelling of NusA produces a pause enhancement complex|
C Ma, M Mobli, X Yang, AN Keller, GF King, PJ Lewis
Nucleic acids research 43 (5), 2829-2840, 2015
|Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine†…|
W Li, H Sun, F Xu, W Shuai, J Liu, S Xu, H Yao, C Ma, Z Zhu, J Xu
Bioorganic Chemistry 85, 49-59, 2019
|Bacterial sliding clamp inhibitors that mimic the sequential binding mechanism of endogenous linear motifs|
Z Yin, LR Whittell, Y Wang, S Jergic, C Ma, PJ Lewis, NE Dixon, JL Beck, ...
Journal of medicinal chemistry 58 (11), 4693-4702, 2015
|Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation|
M Mielczarek, RV Thomas, C Ma, H Kandemir, X Yang, M Bhadbhade, ...
Bioorganic & Medicinal Chemistry 23 (8), 1763-1775, 2015
|Bacterial transcription inhibitor of RNA polymerase holoenzyme formation by structure-based drug design: from in silico screening to validation|
C Ma, X Yang, PJ Lewis
ACS infectious diseases 2 (1), 39-46, 2016
|Synthesis and antibacterial evaluation of novel 3-substituted ocotillol-type derivatives as leads|
Y Bi, XX Liu, HY Zhang, X Yang, ZY Liu, J Lu, PJ Lewis, CZ Wang, JY Xu, ...
Molecules 22 (4), 590, 2017
|Synthesis and Antibacterial Evaluation of Novel Hydrophilic Ocotillol-Type Triterpenoid Derivatives from 20(S)- Protopanaxadiol|
Y Bi, C Ma, Z Zhou, T Zhang, H Zhang, X Zhang, J Lu, Q Meng, PJ Lewis, J Xu
Records of Natural Products 9 (3), 356-368, 2015
|Highly efficient synthesis of the tricyclic core of taxol by cascade metathesis|
A Letort, R Aouzal, C Ma, DL Long, J Prunet
Organic letters 16 (12), 3300-3303, 2014
|EPHB2 activates β-catenin to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma|
HW Leung, CON Leung, EY Lau, KPS Chung, EH Mok, MML Lei, ...
Cancer Research 81 (12), 3229-3240, 2021
|Cascade metathesis reactions for the synthesis of taxane and isotaxane derivatives|
C Ma, A Letort, R Aouzal, A Wilkes, G Maiti, LJ Farrugia, L Ricard, ...
Chemistry–A European Journal 22 (20), 6891-6898, 2016