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| Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants AT Dinkova-Kostova, WD Holtzclaw, RN Cole, K Itoh, N Wakabayashi, ... Proceedings of the National Academy of Sciences 99 (18), 11908-11913, 2002 | 2089 | 2002 |
| The Nrf2 regulatory network provides an interface between redox and intermediary metabolism JD Hayes, AT Dinkova-Kostova Trends in biochemical sciences 39 (4), 199-218, 2014 | 1473 | 2014 |
| Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers N Wakabayashi, AT Dinkova-Kostova, WD Holtzclaw, MI Kang, ... Proceedings of the National Academy of Sciences 101 (7), 2040-2045, 2004 | 1072 | 2004 |
| The cytoprotective role of the Keap1–Nrf2 pathway L Baird, AT Dinkova-Kostova Archives of toxicology 85 (4), 241-272, 2011 | 971 | 2011 |
| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 799 | 2018 |
| Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups AT Dinkova-Kostova, MA Massiah, RE Bozak, RJ Hicks, P Talalay Proceedings of the National Academy of Sciences 98 (6), 3404-3409, 2001 | 667 | 2001 |
| NAD (P) H: quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector AT Dinkova-Kostova, P Talalay Archives of biochemistry and biophysics 501 (1), 116-123, 2010 | 651 | 2010 |
| The emerging role of Nrf2 in mitochondrial function AT Dinkova-Kostova, AY Abramov Free Radical Biology and Medicine 88, 179-188, 2015 | 630 | 2015 |
| Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease LE Tebay, H Robertson, ST Durant, SR Vitale, TM Penning, ... Free Radical Biology and Medicine 88, 108-146, 2015 | 616 | 2015 |
| Direct and indirect antioxidant properties of inducers of cytoprotective proteins AT Dinkova‐Kostova, P Talalay Molecular nutrition & food research 52 (S1), S128-S138, 2008 | 616 | 2008 |
| Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress AT Dinkova-Kostova, KT Liby, KK Stephenson, WD Holtzclaw, X Gao, ... Proceedings of the National Academy of Sciences 102 (12), 4584-4589, 2005 | 615 | 2005 |
| Glucosinolates and isothiocyanates in health and disease AT Dinkova-Kostova, RV Kostov Trends in molecular medicine 18 (6), 337-347, 2012 | 579 | 2012 |
| Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases A Cuadrado, AI Rojo, G Wells, JD Hayes, SP Cousin, WL Rumsey, ... Nature reviews Drug discovery 18 (4), 295-317, 2019 | 571 | 2019 |
| Cancer chemoprevention mechanisms mediated through the Keap1–Nrf2 pathway JD Hayes, M McMahon, S Chowdhry, AT Dinkova-Kostova Antioxidants & redox signaling 13 (11), 1713-1748, 2010 | 547 | 2010 |
| Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders V Calabrese, C Cornelius, AT Dinkova-Kostova, EJ Calabrese, ... Antioxidants & redox signaling 13 (11), 1763-1811, 2010 | 525 | 2010 |
| Oxidative stress in cancer JD Hayes, AT Dinkova-Kostova, KD Tew Cancer cell 38 (2), 167-197, 2020 | 506 | 2020 |
| Nrf2 regulates ROS production by mitochondria and NADPH oxidase S Kovac, PR Angelova, KM Holmström, Y Zhang, AT Dinkova-Kostova, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 794-801, 2015 | 444 | 2015 |
| Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans L Ye, AT Dinkova-Kostova, KL Wade, Y Zhang, TA Shapiro, P Talalay Clinica chimica acta 316 (1-2), 43-53, 2002 | 415 | 2002 |
| The role of Keap1 in cellular protective responses AT Dinkova-Kostova, WD Holtzclaw, TW Kensler Chemical research in toxicology 18 (12), 1779-1791, 2005 | 401 | 2005 |
