Albena T. Dinkova-Kostova
Albena T. Dinkova-Kostova
Professor of Chemical Biology, University of Dundee
Verified email at dundee.ac.uk
Title
Cited by
Cited by
Year
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
AT Dinkova-Kostova, WD Holtzclaw, RN Cole, K Itoh, N Wakabayashi, ...
Proceedings of the National Academy of Sciences 99 (18), 11908-11913, 2002
18842002
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
JD Hayes, AT Dinkova-Kostova
Trends in biochemical sciences 39 (4), 199-218, 2014
10852014
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers
N Wakabayashi, AT Dinkova-Kostova, WD Holtzclaw, MI Kang, ...
Proceedings of the National Academy of Sciences 101 (7), 2040-2045, 2004
9892004
The cytoprotective role of the Keap1–Nrf2 pathway
L Baird, AT Dinkova-Kostova
Archives of toxicology 85 (4), 241-272, 2011
8172011
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups
AT Dinkova-Kostova, MA Massiah, RE Bozak, RJ Hicks, P Talalay
Proceedings of the National Academy of Sciences 98 (6), 3404-3409, 2001
6242001
Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress
AT Dinkova-Kostova, KT Liby, KK Stephenson, WD Holtzclaw, X Gao, ...
Proceedings of the National Academy of Sciences 102 (12), 4584-4589, 2005
5622005
NAD (P) H: quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
AT Dinkova-Kostova, P Talalay
Archives of biochemistry and biophysics 501 (1), 116-123, 2010
5512010
Direct and indirect antioxidant properties of inducers of cytoprotective proteins
AT Dinkova‐Kostova, P Talalay
Molecular nutrition & food research 52 (S1), S128-S138, 2008
5472008
Cancer chemoprevention mechanisms mediated through the Keap1–Nrf2 pathway
JD Hayes, M McMahon, S Chowdhry, AT Dinkova-Kostova
Antioxidants & redox signaling 13 (11), 1713-1748, 2010
4812010
Glucosinolates and isothiocyanates in health and disease
AT Dinkova-Kostova, RV Kostov
Trends in molecular medicine 18 (6), 337-347, 2012
4442012
The emerging role of Nrf2 in mitochondrial function
AT Dinkova-Kostova, AY Abramov
Free Radical Biology and Medicine 88, 179-188, 2015
4412015
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
LE Tebay, H Robertson, ST Durant, SR Vitale, TM Penning, ...
Free Radical Biology and Medicine 88, 108-146, 2015
4342015
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
4122018
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders
V Calabrese, C Cornelius, AT Dinkova-Kostova, EJ Calabrese, ...
Antioxidants & redox signaling 13 (11), 1763-1811, 2010
3852010
The role of Keap1 in cellular protective responses
AT Dinkova-Kostova, WD Holtzclaw, TW Kensler
Chemical research in toxicology 18 (12), 1779-1791, 2005
3762005
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans
L Ye, AT Dinkova-Kostova, KL Wade, Y Zhang, TA Shapiro, P Talalay
Clinica chimica acta 316 (1-2), 43-53, 2002
3752002
Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity
V Calabrese, C Cornelius, AT Dinkova-Kostova, I Iavicoli, R Di Paola, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (5), 753-783, 2012
3332012
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast
BS Cornblatt, L Ye, AT Dinkova-Kostova, M Erb, JW Fahey, NK Singh, ...
Carcinogenesis 28 (7), 1485-1490, 2007
3282007
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study
TA Shapiro, JW Fahey, AT Dinkova-Kostova, WD Holtzclaw, ...
Nutrition and cancer 55 (1), 53-62, 2006
3242006
Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis
P Talalay, AT Dinkova-Kostova, WD Holtzclaw
Advances in enzyme regulation 43, 121-134, 2003
3242003
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