Vivek Modi
Vivek Modi
Investigator, GSK, Stevenage, UK
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Defining a new nomenclature for the structures of active and inactive kinases
V Modi, RL Dunbrack Jr
Proceedings of the National Academy of Sciences 116 (14), 6818-6827, 2019
Conformational analysis of the DFG-out kinase motif and biochemical profiling of structurally validated type II inhibitors
RSK Vijayan, P He, V Modi, KC Duong-Ly, H Ma, JR Peterson, ...
Journal of medicinal chemistry 58 (1), 466-479, 2015
A structurally-validated multiple sequence alignment of 497 human protein kinase domains
V Modi, RL Dunbrack Jr
Scientific reports 9 (1), 19790, 2019
Kincore: a web resource for structural classification of protein kinases and their inhibitors
V Modi, RL Dunbrack Jr
Nucleic Acids Research 50 (D1), D654-D664, 2022
Assessment of refinement of template‐based models in CASP11
V Modi, RL Dunbrack Jr
Proteins: Structure, Function, and Bioinformatics 84, 260-281, 2016
Assessment of template‐based modeling of protein structure in CASP11
V Modi, Q Xu, S Adhikari, RL Dunbrack Jr
Proteins: Structure, Function, and Bioinformatics 84, 200-220, 2016
PDBe-KB: collaboratively defining the biological context of structural data
Nucleic acids research 50 (D1), D534-D542, 2022
Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent
V Modi, D Lama, R Sankararamakrishnan
Journal of Biomolecular Structure and Dynamics 31 (1), 65-77, 2013
Behavior of Solvent-Exposed Hydrophobic Groove in the Anti-Apoptotic Bcl-XL Protein: Clues for Its Ability to Bind Diverse BH3 Ligands from MD Simulations
D Lama, V Modi, R Sankararamakrishnan
Plos one 8 (2), e54397, 2013
Biological function derived from predicted structures in CASP11
PJ Huwe, Q Xu, MV Shapovalov, V Modi, MD Andrake, RL Dunbrack Jr
Proteins: Structure, Function, and Bioinformatics 84, 370-391, 2016
Binding affinity of pro-apoptotic BH3 peptides for the anti-apoptotic Mcl-1 and A1 proteins: Molecular dynamics simulations of Mcl-1 and A1 in complex with six different BH3 …
V Modi, R Sankararamakrishnan
Journal of Molecular Graphics and Modelling 73, 115-128, 2017
Antiapoptotic Bcl‐2 homolog CED‐9 in Caenorhabditis elegans: Dynamics of BH3 and CED‐4 binding regions and comparison with mammalian antiapoptotic Bcl …
V Modi, R Sankararamakrishnan
Proteins: Structure, Function, and Bioinformatics 82 (6), 1035-1047, 2014
Clustering of the structures of protein kinase activation loops: A new nomenclature for active and inactive kinase structures
V Modi, RL Dunbrack Jr
bioRxiv, 395723, 2018
Plasticity of BH3 domain-binding hydrophobic grooves in the anti-apoptotic Mcl-1 and A1 proteins
Biomolecular Forms and Functions: A Celebration of 50 Years of the …, 2013
A Structurally Validated Sequence Alignment of All 497 Typical Human Protein Kinase Domains
V Modi, RL Dunbrack Jr
bioRxiv, 776740, 2019
Acute coronary events in patients with myeloproliferative neoplasms-a nationwide analysis of patient characteristics and in-hospital outcomes
K Bhatia, S Handa, S Das, V Modi, A Joshi
European Heart Journal 41 (Supplement_2), ehaa946. 1630, 2020
Binding Affinity of Pro-apoptotic BH3 peptides for the
V Modi, R Sankararamakrishnan
prospects 111 (7), 3322-30, 2013
Differential Binding Affinities of Anti-Apoptotic MCL-1 and A1 Proteins for the Pro-Apoptotic BH3 Peptides: Understanding the Molecular Basis using MD Simulations
V Modi, D Lama, R Sankararamakrishnan
Biophysical Journal 100 (3), 396a, 2011
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