| Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ... Science 324 (5933), 1457-1461, 2009 | 3574 | 2009 |
| Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ... Cancer cell 25 (6), 735-747, 2014 | 2081 | 2014 |
| Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome KP Olive, DA Tuveson, ZC Ruhe, B Yin, NA Willis, RT Bronson, D Crowley, ... Cell 119 (6), 847-860, 2004 | 1506 | 2004 |
| Stromal biology and therapy in pancreatic cancer A Neesse, P Michl, KK Frese, C Feig, N Cook, MA Jacobetz, MP Lolkema, ... Gut 60 (6), 861-868, 2011 | 914 | 2011 |
| Cysteine depletion induces pancreatic tumor ferroptosis in mice MA Badgley, DM Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ... Science 368 (6486), 85-89, 2020 | 900 | 2020 |
| The differential effects of mutant p53 alleles on advanced murine lung cancer EL Jackson, KP Olive, DA Tuveson, R Bronson, D Crowley, M Brown, ... Cancer research 65 (22), 10280-10288, 2005 | 621 | 2005 |
| Pancreatic cancer: why is it so hard to treat? PE Oberstein, KP Olive Therapeutic advances in gastroenterology 6 (4), 321-337, 2013 | 432 | 2013 |
| β2 adrenergic-neurotrophin feedforward loop promotes pancreatic cancer BW Renz, R Takahashi, T Tanaka, M Macchini, Y Hayakawa, Z Dantes, ... Cancer cell 33 (1), 75-90. e7, 2018 | 399 | 2018 |
| Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging S Harmsen, R Huang, MA Wall, H Karabeber, JM Samii, M Spaliviero, ... Science translational medicine 7 (271), 271ra7-271ra7, 2015 | 304 | 2015 |
| The use of targeted mouse models for preclinical testing of novel cancer therapeutics KP Olive, DA Tuveson Clinical Cancer Research 12 (18), 5277-5287, 2006 | 302 | 2006 |
| Multivalent small-molecule pan-RAS inhibitors ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ... Cell 168 (5), 878-889. e29, 2017 | 273 | 2017 |
| Dclk1 defines quiescent pancreatic progenitors that promote injury-induced regeneration and tumorigenesis CB Westphalen, Y Takemoto, T Tanaka, M Macchini, Z Jiang, BW Renz, ... Cell stem cell 18 (4), 441-455, 2016 | 230 | 2016 |
| Cholinergic signaling via muscarinic receptors directly and indirectly suppresses pancreatic tumorigenesis and cancer stemness BW Renz, T Tanaka, M Sunagawa, R Takahashi, Z Jiang, M Macchini, ... Cancer discovery 8 (11), 1458-1473, 2018 | 212 | 2018 |
| Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts S Bhattacharjee, F Hamberger, A Ravichandra, M Miller, A Nair, S Affo, ... The Journal of clinical investigation 131 (11), 2024 | 203 | 2024 |
| Experimental microdissection enables functional harmonisation of pancreatic cancer subtypes C Maurer, SR Holmstrom, J He, P Laise, T Su, A Ahmed, H Hibshoosh, ... Gut 68 (6), 1034-1043, 2019 | 191 | 2019 |
| Germline Brca2 heterozygosity promotes KrasG12D-driven carcinogenesis in a murine model of familial pancreatic cancer F Skoulidis, LD Cassidy, V Pisupati, JG Jonasson, H Bjarnason, ... Cancer cell 18 (5), 499-509, 2010 | 184 | 2010 |
| The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer KA Michaelis, MA Norgard, X Zhu, PR Levasseur, S Sivagnanam, ... Nature communications 10 (1), 4682, 2019 | 178 | 2019 |
| GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature communications 12 (1), 4860, 2021 | 170 | 2021 |
| Genetically engineered mouse models of pancreatic cancer CB Westphalen, KP Olive The Cancer Journal 18 (6), 502-510, 2012 | 155 | 2012 |
| Current and emerging therapies in metastatic pancreatic cancer GA Manji, KP Olive, YM Saenger, P Oberstein Clinical Cancer Research 23 (7), 1670-1678, 2017 | 144 | 2017 |
