R.L.H. Spätjens
R.L.H. Spätjens
Maastricht University, Cardiovascular Research Institute Maastricht, Dept. of Cardiology
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Cited by
Cited by
Downregulation of delayed rectifier K+ currents in dogs with chronic complete atrioventricular block and acquired torsades de pointes
PGA Volders, KR Sipido, MA Vos, RL Spätjens, JDM Leunissen, ...
Circulation 100 (24), 2455-2461, 1999
Probing the contribution of IKs to canine ventricular repolarization: key role for β-adrenergic receptor stimulation
PGA Volders, M Stengl, JM van Opstal, U Gerlach, RL Spätjens, ...
Circulation 107 (21), 2753-2760, 2003
Repolarizing K+ currents ITO1 and IKs are larger in right than left canine ventricular midmyocardium
PGA Volders, KR Sipido, E Carmeliet, RL Spätjens, HJJ Wellens, MA Vos
Circulation 99 (2), 206-210, 1999
Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes
M Stengl, PGA Volders, MB Thomsen, RL Spätjens, KR Sipido, MA Vos
The Journal of Physiology 551 (3), 777-786, 2003
Electrophysiological safety of sertindole in dogs with normal and remodeled hearts
MB Thomsen, PGA Volders, M Stengl, RL Spätjens, JDM Beekman, ...
Journal of Pharmacology and Experimental Therapeutics 307 (2), 776-784, 2003
Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1
J Heijman, RL Spätjens, SRM Seyen, V Lentink, HJH Kuijpers, IR Boulet, ...
Circulation Research 110 (2), 211-219, 2012
Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1
J Heijman, RL Spätjens, SR Seyen, V Lentink, HJ Kuijpers, IR Boulet, ...
Circulation 124 (Suppl 21), A10189-A10189, 2011
Temporal patterns of electrical remodeling in canine ventricular hypertrophy: Focus on IKs downregulation and blunted β-adrenergic activation
M Stengl, C Ramakers, DW Donker, A Nabar, AV Rybin, RL Spätjens, ...
Cardiovascular research 72 (1), 90-100, 2006
Interventricular Differences in β‐Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases
CE Molina, DM Johnson, H Mehel, RL Spätjens, D Mika, V Algalarrondo, ...
Journal of the American Heart Association 3 (3), e000858, 2014
End–diastolic myofiber stress and ejection strain increase with ventricular volume overload: Serial in–vivo analyses in dogs with complete atrioventricular block
DW Donker, PGA Volders, T Arts, BCAM Bekkers, L Hofstra, R Spätjens, ...
Basic research in cardiology 100, 372-382, 2005
Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium
DW Donker, JG Maessen, F Verheyen, FC Ramaekers, RL Spätjens, ...
American Journal of Physiology-Heart and Circulatory Physiology 292 (5 …, 2007
Molecular and electrical characterization of the canine cardiac ventricular septum
C Ramakers, M Stengl, RL Spätjens, AFM Moorman, MA Vos
Journal of molecular and cellular cardiology 38 (1), 153-161, 2005
Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region
P Schwartz, C Moreno, MC Kotta, M Pedrazzini, L Crotti, F Dagradi, ...
European Heart Journal, 2021
Long-QT mutation p. K557E-Kv7. 1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation
RL Spätjens, M Bébarová, SRM Seyen, V Lentink, RJ Jongbloed, ...
Cardiovascular research 104 (1), 216-225, 2014
Repolarization instability and arrhythmia by IKr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers
C Altrocchi, T de Korte, J Bernardi, RL Spätjens, SR Braam, J Heijman, ...
EP Europace 22 (9), 1431-1441, 2020
Measurement of Action Potential Generation in Isolated Canine Left Ventricular Midmyocardial Myocytes
DM Johnson, L Hussein, RL Spätjens, JP Valentin, PGA Volders, ...
Current Protocols in Pharmacology, 2011
Electrophysiological and proarrhythmic parameters in transmural canine left-ventricular needle biopsies
SC Verduyn, JGM Jungschleger, M Stengl, RL Spätjens, JDM Beekman, ...
Pflügers Archiv 449, 115-122, 2004
Serial left-ventricular biopsy sampling using a minimally invasive trans-thoracic approach in adult dogs
DW Donker, JG Maessen, RL Spätjens, T van der Nagel, M de Jong, ...
Pflügers Archiv-European Journal of Physiology 454 (6), 1043-1051, 2007
Accumulation of slow delayed rectifier K+ current (I-Ks) in canine ventricular myocytes
M Stengl, MA Vos, R Spatjens, KR Sipido, PGA Volders
BIOPHYSICAL JOURNAL 82 (1), 606A-606A, 2002
Cardiomyocyte cell cycle activity and function is under the control of miR-125a
R Verjans, L Braga, M Rech, S Beijnsberger, P Carai, R Spatjens, ...
Cardiovascular Research 114 (suppl_1), S18-S18, 2018
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