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Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics
R Pascal, A Pross, JD Sutherland
Open biology 3 (11), 130156, 2013
Pathways for the formation and evolution of peptides in prebiotic environments
G Danger, R Plasson, R Pascal
Chemical Society Reviews 41 (16), 5416-5429, 2012
From the prebiotic synthesis of α-amino acids towards a primitive translation apparatus for the synthesis of peptides
R Pascal, L Boiteau, A Commeyras
Prebiotic chemistry, 69-122, 2005
The origin of life: what we know, what we can know and what we will never know
A Pross, R Pascal
Open biology 3 (3), 120190, 2013
Preservation of the protective group under alkaline conditions by using CaCl2. Applications in peptide synthesis
R Pascal, R Sola
Tetrahedron letters 39 (28), 5031-5034, 1998
The Peptide Formation Mediated by Cyanate Revisited. N-Carboxyanhydrides as Accessible Intermediates in the Decomposition of N-Carbamoylamino Acids
G Danger, L Boiteau, H Cottet, R Pascal
Journal of the American Chemical Society 128 (23), 7412-7413, 2006
An Expeditious Multigram‐Scale Synthesis of Lysine Dendrigraft (DGL) Polymers by Aqueous N‐Carboxyanhydride Polycondensation
H Collet, E Souaid, H Cottet, A Deratani, L Boiteau, G Dessalces, ...
Chemistry–A European Journal 16 (7), 2309-2316, 2010
Expeditious, potentially primordial, aminoacylation of nucleotides
JP Biron, AL Parkes, R Pascal, JD Sutherland
Angewandte Chemie 117 (41), 6889-6892, 2005
A strategy for origins of life research
C Scharf, N Virgo, HJ Cleaves, M Aono, N Aubert-Kato, A Aydinoglu, ...
Astrobiology 15 (12), 1031-1042, 2015
Stability and its manifestation in the chemical and biological worlds
R Pascal, A Pross
Chemical Communications 51 (90), 16160-16165, 2015
Mapping a systematic ribozyme fitness landscape reveals a frustrated evolutionary network for self-aminoacylating RNA
AD Pressman, Z Liu, E Janzen, C Blanco, UF Müller, GF Joyce, ...
Journal of the American Chemical Society 141 (15), 6213-6223, 2019
A computational analysis of intramolecularity in proton transfer reactions
R Karaman, R Pascal
Organic & biomolecular chemistry 8 (22), 5174-5178, 2010
Amino acid N-carboxyanhydrides: activated peptide monomers behaving as phosphate-activating agents in aqueous solution
JP Biron, R Pascal
Journal of the American Chemical Society 126 (30), 9198-9199, 2004
Astrobiology and the possibility of life on earth and elsewhere…
H Cottin, JM Kotler, K Bartik, HJ Cleaves, CS Cockell, JPP De Vera, ...
Space Science Reviews 209, 1-42, 2017
5(4H)‐Oxazolones as Intermediates in the Carbodiimide‐ and Cyanamide‐Promoted Peptide Activations in Aqueous Solution
G Danger, A Michaut, M Bucchi, L Boiteau, J Canal, R Plasson, R Pascal
Angewandte Chemie International Edition 52 (2), 611-614, 2013
Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide
S Murillo-Sánchez, D Beaufils, JMG Mañas, R Pascal, K Ruiz-Mirazo
Chemical Science 7 (5), 3406-3413, 2016
Catalysis through induced intramolecularity: what can be learned by mimicking enzymes with carbonyl compounds that covalently bind substrates?
R Pascal
European Journal of Organic Chemistry 2003 (10), 1813-1824, 2003
Systemes de Strecker et apparentes—X: decomposition et hydratation en milieu aqueux basique des α-aminonitriles secondaires. Processus d'hydratation autocatalytique et …
R Pascal, J Taillades, A Commeyras
Tetrahedron 34 (15), 2275-2281, 1978
A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein
S Granier, S Terrillon, R Pascal, H Déméné, M Bouvier, G Guillon, ...
Journal of Biological Chemistry 279 (49), 50904-50914, 2004
Dynamic co-evolution of peptides and chemical energetics, a gateway to the emergence of homochirality and the catalytic activity of peptides
A Commeyras, J Taillades, H Collet, L Boiteau, ...
Origins of Life and Evolution of the Biosphere 34, 35-55, 2004
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