Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancer M Isikbay, K Otto, S Kregel, J Kach, Y Cai, DJ Vander Griend, SD Conzen, ... Hormones and Cancer 5, 72-89, 2014 | 325 | 2014 |
The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression YS Niknafs, S Han, T Ma, C Speers, C Zhang, K Wilder-Romans, MK Iyer, ... Nature communications 7 (1), 12791, 2016 | 207 | 2016 |
Biologically informed deep neural network for prostate cancer discovery HA Elmarakeby, J Hwang, R Arafeh, J Crowdis, S Gang, D Liu, ... Nature 598 (7880), 348-352, 2021 | 200 | 2021 |
Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer S Kregel, KJ Kiriluk, AM Rosen, Y Cai, EE Reyes, KB Otto, W Tom, ... PloS one 8 (1), e53701, 2013 | 190 | 2013 |
Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2 Y Qiao, XM Wang, R Mannan, S Pitchiaya, Y Zhang, JW Wotring, L Xiao, ... Proceedings of the National Academy of Sciences 118 (1), e2021450118, 2021 | 173 | 2021 |
Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-β N Sandbo, S Kregel, S Taurin, S Bhorade, NO Dulin American journal of respiratory cell and molecular biology 41 (3), 332-338, 2009 | 127 | 2009 |
Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer A Urbanucci, SJ Barfeld, V Kytölä, HM Itkonen, IM Coleman, D Vodák, ... Cell reports 19 (10), 2045-2059, 2017 | 123 | 2017 |
Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment S Kregel, C Wang, X Han, L Xiao, E Fernandez-Salas, P Bawa, ... Neoplasia 22 (2), 111-119, 2020 | 122 | 2020 |
Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer L Xiao, A Parolia, Y Qiao, P Bawa, S Eyunni, R Mannan, SE Carson, ... Nature 601 (7893), 434-439, 2022 | 118 | 2022 |
Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer S Kregel, JL Chen, W Tom, V Krishnan, J Kach, H Brechka, TB Fessenden, ... Oncotarget 7 (18), 26259, 2016 | 105 | 2016 |
Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2 N Sandbo, C Ngam, E Torr, S Kregel, J Kach, N Dulin Journal of Biological Chemistry 288 (22), 15466-15473, 2013 | 67 | 2013 |
The pluripotency factor Nanog is directly upregulated by the androgen receptor in prostate cancer cells S Kregel, RZ Szmulewitz, DJV Griend The Prostate 74 (15), 1530-1543, 2014 | 36 | 2014 |
Downregulation of smooth muscle α-actin expression by bacterial lipopolysaccharide N Sandbo, S Taurin, DM Yau, S Kregel, R Mitchell, NO Dulin Cardiovascular research 74 (2), 262-269, 2007 | 32 | 2007 |
Functional and mechanistic interrogation of BET bromodomain degraders for the treatment of metastatic castration-resistant prostate cancer S Kregel, R Malik, IA Asangani, K Wilder-Romans, T Rajendiran, L Xiao, ... Clinical Cancer Research 25 (13), 4038-4048, 2019 | 29 | 2019 |
The 2014 international society of urological pathology (ISUP) consensus conference on gleason grading of prostatic carcinoma definition of grading patterns and proposal for a … Grading Committee American Journal of Surgical Pathology 40 (2), 244-252, 2016 | 28 | 2016 |
SOX2 mediates metabolic reprogramming of prostate cancer cells L de Wet, A Williams, M Gillard, S Kregel, S Lamperis, LC Gutgesell, ... Oncogene 41 (8), 1190-1202, 2022 | 26 | 2022 |
PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer EP Darga, EM Dolce, F Fang, KM Kidwell, CL Gersch, S Kregel, ... PLoS One 16 (11), e0260124, 2021 | 26 | 2021 |
Regulation of Smad-mediated gene transcription by RGS3 DM Yau, N Sethakorn, S Taurin, S Kregel, N Sandbo, ... Molecular pharmacology 73 (5), 1356-1361, 2008 | 25 | 2008 |
Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element S Kregel, P Bagamasbad, S He, E LaPensee, Y Raji, M Brogley, ... Nucleic acids research 48 (9), 4741-4755, 2020 | 24 | 2020 |
Molecular analysis of CD133-positive circulating tumor cells from patients with metastatic castration-resistant prostate cancer EE Reyes, M Gillard, R Duggan, K Wroblewski, S Kregel, M Isikbay, ... Journal of translational science 1 (1), 2015 | 22 | 2015 |