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Douglas Kojetin
Douglas Kojetin
Vanderbilt University, Department of Biochemistry, Center for Structural Biology
Bestätigte E-Mail-Adresse bei vanderbilt.edu - Startseite
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Zitiert von
Zitiert von
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Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
LA Solt, Y Wang, S Banerjee, T Hughes, DJ Kojetin, T Lundasen, Y Shin, ...
Nature 485 (7396), 62-68, 2012
7772012
REV-ERB and ROR nuclear receptors as drug targets
DJ Kojetin, TP Burris
Nature reviews Drug discovery 13 (3), 197-216, 2014
5342014
Nuclear receptors and their selective pharmacologic modulators
TP Burris, LA Solt, Y Wang, C Crumbley, S Banerjee, K Griffett, ...
Pharmacological reviews 65 (2), 710-778, 2013
2852013
DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex
J Zhang, MJ Chalmers, KR Stayrook, LL Burris, Y Wang, SA Busby, ...
Nature structural & molecular biology 18 (5), 556-563, 2011
2262011
An alternate binding site for PPARγ ligands
TS Hughes, PK Giri, IMS De Vera, DP Marciano, DS Kuruvilla, Y Shin, ...
Nature communications 5 (1), 3571, 2014
1822014
The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis
LA Solt, DJ Kojetin, TP Burris
Future medicinal chemistry 3 (5), 623-638, 2011
1792011
Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REV-ERB
D Kojetin, Y Wang, TM Kamenecka, TP Burris
ACS chemical biology 6 (2), 131-134, 2011
1742011
Characterization of the core mammalian clock component, NPAS2, as a REV-ERBα/RORα target gene
C Crumbley, Y Wang, DJ Kojetin, TP Burris
Journal of Biological Chemistry 285 (46), 35386-35392, 2010
1712010
Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism
TS Hughes, MJ Chalmers, S Novick, DS Kuruvilla, MR Chang, ...
Structure 20 (1), 139-150, 2012
1692012
Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network
JC Nwachukwu, S Srinivasan, NE Bruno, AA Parent, TS Hughes, ...
elife 3, e02057, 2014
1422014
Structural mechanism for signal transduction in RXR nuclear receptor heterodimers
DJ Kojetin, E Matta-Camacho, TS Hughes, S Srinivasan, JC Nwachukwu, ...
Nature communications 6 (1), 8013, 2015
1322015
Small molecule modulation of nuclear receptor conformational dynamics: implications for function and drug discovery
DJ Kojetin, TP Burris
Molecular pharmacology 83 (1), 1-8, 2013
1312013
Conserved sequence-specific lincRNA–steroid receptor interactions drive transcriptional repression and direct cell fate
WH Hudson, MR Pickard, IMS De Vera, EG Kuiper, ...
Nature communications 5 (1), 5395, 2014
1232014
Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist
N Kumar, DJ Kojetin, LA Solt, KG Kumar, P Nuhant, DR Duckett, ...
ACS chemical biology 6 (3), 218-222, 2011
1232011
Pharmacological repression of PPARγ promotes osteogenesis
DP Marciano, DS Kuruvilla, SV Boregowda, A Asteian, TS Hughes, ...
Nature communications 6 (1), 7443, 2015
1182015
Ebselen, a small-molecule capsid inhibitor of HIV-1 replication
S Thenin-Houssier, IMS De Vera, L Pedro-Rosa, A Brady, A Richard, ...
Antimicrobial agents and chemotherapy 60 (4), 2195-2208, 2016
1112016
Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D28K
DJ Kojetin, RA Venters, DR Kordys, RJ Thompson, R Kumar, J Cavanagh
Nature structural & molecular biology 13 (7), 641-647, 2006
1102006
Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements
WH Hudson, IMS Vera, JC Nwachukwu, ER Weikum, AG Herbst, Q Yang, ...
Nature communications 9 (1), 1337, 2018
1072018
PGRMC2 is an intracellular haem chaperone critical for adipocyte function
A Galmozzi, BP Kok, AS Kim, JR Montenegro-Burke, JY Lee, R Spreafico, ...
Nature 576 (7785), 138-142, 2019
952019
REV-ERBα regulates TH17 cell development and autoimmunity
M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, ...
Cell reports 25 (13), 3733-3749. e8, 2018
892018
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