| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1278 | 2018 |
| Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 JO Early, D Menon, CA Wyse, MP Cervantes-Silva, Z Zaslona, RG Carroll, ... Proceedings of the National Academy of Sciences 115 (36), E8460-E8468, 2018 | 277 | 2018 |
| Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma Z Zasłona, S Przybranowski, C Wilke, N van Rooijen, ... The Journal of Immunology 193 (8), 4245-4253, 2014 | 225 | 2014 |
| Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling E Bourdonnay, Z Zasłona, LRK Penke, JM Speth, DJ Schneider, ... Journal of Experimental Medicine 212 (5), 729-742, 2015 | 220 | 2015 |
| An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation RG Carroll, Z Zasłona, S Galván-Peña, EL Koppe, DC Sévin, S Angiari, ... Journal of Biological Chemistry 293 (15), 5509-5521, 2018 | 162 | 2018 |
| Pyruvate kinase M2 is required for the expression of the immune checkpoint PD-L1 in immune cells and tumors EM Palsson-McDermott, L Dyck, Z Zasłona, D Menon, AF McGettrick, ... Frontiers in immunology 8, 1300, 2017 | 148 | 2017 |
| Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts SK Huang, AM Scruggs, J Donaghy, JC Horowitz, Z Zaslona, ... Cell death & disease 4 (5), e621-e621, 2013 | 145 | 2013 |
| Cytokine-like roles for metabolites in immunity Z Zasłona, LAJ O’Neill Molecular cell 78 (5), 814-823, 2020 | 139 | 2020 |
| Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease CE Sutton, CM Finlay, M Raverdeau, JO Early, J DeCourcey, Z Zaslona, ... Nature communications 8 (1), 1923, 2017 | 113 | 2017 |
| The induction of pro–IL-1β by lipopolysaccharide requires endogenous prostaglandin E2 production Z Zasłona, EM Pålsson-McDermott, D Menon, M Haneklaus, E Flis, ... The Journal of Immunology 198 (9), 3558-3564, 2017 | 97 | 2017 |
| Specific inhibition of the NLRP3 inflammasome as an antiinflammatory strategy in cystic fibrosis OJ McElvaney, Z Zaslona, K Becker-Flegler, EM Palsson-McDermott, ... American journal of respiratory and critical care medicine 200 (11), 1381-1391, 2019 | 92 | 2019 |
| Serotonin activates murine alveolar macrophages through 5-HT2C receptors Z Mikulski, Z Zasłona, L Cakarova, P Hartmann, J Wilhelm, LH Tecott, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 299 (2 …, 2010 | 86 | 2010 |
| Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells Z Zasłona, K Okunishi, E Bourdonnay, R Domingo-Gonzalez, BB Moore, ... Journal of allergy and clinical immunology 133 (2), 379-387. e1, 2014 | 85 | 2014 |
| Distinct protein kinase A anchoring proteins direct prostaglandin E2 modulation of Toll-like receptor signaling in alveolar macrophages SH Kim, CH Serezani, K Okunishi, Z Zaslona, DM Aronoff, ... Journal of Biological Chemistry 286 (11), 8875-8883, 2011 | 80 | 2011 |
| Dysregulation of the IL-13 receptor system. a novel pathomechanism in pulmonary arterial hypertension M Hecker, Z Zasłona, G Kwapiszewska, G Niess, A Zakrzewicz, ... American journal of respiratory and critical care medicine 182 (6), 805-818, 2010 | 79 | 2010 |
| Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling Z Zasłona, CH Serezani, K Okunishi, DM Aronoff, M Peters-Golden Blood, The Journal of the American Society of Hematology 119 (10), 2358-2367, 2012 | 74 | 2012 |
| Glutathione transferase omega-1 regulates NLRP3 inflammasome activation through NEK7 deglutathionylation MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, ... Cell reports 29 (1), 151-161. e5, 2019 | 66 | 2019 |
| Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration Z Mikulski, P Hartmann, G Jositsch, Z Zasłona, KS Lips, U Pfeil, H Kurzen, ... Respiratory research 11, 1-16, 2010 | 65 | 2010 |
| Caspase-11 promotes allergic airway inflammation Z Zasłona, E Flis, MM Wilk, RG Carroll, EM Palsson-McDermott, ... Nature Communications 11 (1), 1055, 2020 | 62 | 2020 |
| Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease RA Colas, PR Souza, ME Walker, M Burton, Z Zasłona, AM Curtis, ... Circulation research 122 (6), 855-863, 2018 | 60 | 2018 |
