OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation C Marchetti, B Swartzwelter, F Gamboni, CP Neff, K Richter, T Azam, ... Proceedings of the National Academy of Sciences 115 (7), E1530-E1539, 2018 | 382 | 2018 |
NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis C Marchetti, B Swartzwelter, MI Koenders, T Azam, IW Tengesdal, ... Arthritis research & therapy 20, 1-11, 2018 | 134 | 2018 |
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease JF Højen, MLV Kristensen, AS McKee, MT Wade, T Azam, LP Lunding, ... Nature immunology 20 (9), 1138-1149, 2019 | 66 | 2019 |
Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue DB Ballak, S Li, G Cavalli, JL Stahl, IW Tengesdal, JA van Diepen, ... Journal of Biological Chemistry 293 (37), 14224-14236, 2018 | 48 | 2018 |
Joosten, LAB; Dinarello, CA OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation C Marchetti, B Swartzwelter, F Gamboni, CP Neff, K Richter, T Azam, ... Proc. Natl. Acad. Sci. USA 115 (7), E1530-E1539, 2018 | 46 | 2018 |
Addressing nanomaterial immunosafety by evaluating innate immunity across living species D Boraschi, A Alijagic, M Auguste, F Barbero, E Ferrari, S Hernadi, ... Small 16 (21), 2000598, 2020 | 42 | 2020 |
Towards bio-compatible magnetic nanoparticles: Immune-related effects, in-vitro internalization, and in-vivo bio-distribution of zwitterionic ferrite nanoparticles with … AM Ferretti, S Usseglio, S Mondini, C Drago, R La Mattina, B Chini, ... Journal of Colloid and Interface Science 582, 678-700, 2021 | 29 | 2021 |
PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis NE Powers, B Swartzwelter, C Marchetti, DM de Graaf, A Lerchner, ... Journal of Biological Chemistry 295 (3), 868-882, 2020 | 27 | 2020 |
Gold nanoparticles modulate BCG-induced innate immune memory in human monocytes by shifting the memory response towards tolerance BJ Swartzwelter, F Barbero, A Verde, M Mangini, M Pirozzi, AC De Luca, ... Cells 9 (2), 284, 2020 | 26 | 2020 |
The impact of nanoparticles on innate immune activation by live bacteria BJ Swartzwelter, AC Fux, L Johnson, E Swart, S Hofer, N Hofstätter, ... International Journal of Molecular Sciences 21 (24), 9695, 2020 | 21 | 2020 |
Cross-species comparisons of nanoparticle interactions with innate immune systems: A methodological review BJ Swartzwelter, C Mayall, A Alijagic, F Barbero, E Ferrari, S Hernadi, ... Nanomaterials 11 (6), 1528, 2021 | 18 | 2021 |
interaction between macrophages and nanoparticles: in vitro 3D cultures for the realistic assessment of inflammatory activation and modulation of innate memory BJ Swartzwelter, A Verde, L Rehak, M Madej, VF Puntes, AC De Luca, ... Nanomaterials 11 (1), 207, 2021 | 17 | 2021 |
Heterogeneity of lipopolysaccharide as source of variability in bioassays and LPS-binding proteins as remedy AC Fux, C Casonato Melo, S Michelini, BJ Swartzwelter, A Neusch, ... International Journal of Molecular Sciences 24 (9), 8395, 2023 | 16 | 2023 |
Personalised profiling of innate immune memory induced by nano-imaging particles in human monocytes G Della Camera, M Madej, AM Ferretti, R La Spina, Y Li, A Corteggio, ... Frontiers in Immunology 12, 692165, 2021 | 15 | 2021 |
Interaction of engineered nanomaterials with the immune system: health-related safety and possible benefits D Boraschi, BJ Swartzwelter, P Italiani Current Opinion in Toxicology 10, 74-83, 2018 | 12 | 2018 |
Surface exposure of PEG and amines on biodegradable nanoparticles as a strategy to tune their interaction with protein-rich biological media C Conte, G Dal Poggetto, B J. Swartzwelter, D Esposito, F Ungaro, ... Nanomaterials 9 (10), 1354, 2019 | 11 | 2019 |
OP0090 The human safe NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of experimental arthritis C Marchetti, B Swartzwelter, MI Koenders, CA Dinarello, LA Joosten Annals of the Rheumatic Diseases 76 (Suppl 2), 89-89, 2017 | 7 | 2017 |
Innate memory reprogramming by gold nanoparticles depends on the microbial agents that induce memory BJ Swartzwelter, S Michelini, T Frauenlob, F Barbero, A Verde, ... Frontiers in immunology 12, 751683, 2021 | 3 | 2021 |
frontiers Frontiers in Immunology ORIGINAL RESEARCH published: 01 July 2022 D Boraschi, P Migliorini, B Swartzwelter, J Yan, Y Li, X Lan, L Guo, S Zhu, ... Women in Cytokines and Soluble Mediators in Immunity, 11, 2024 | | 2024 |
Evolution of innate immunity, lessons learned for assessing safety and efficacy of nanomaterials and nanodrugs D Boraschi, B Swartzwelter, D Melillo, R Marino, G Della Camera, ... ISJ-INVERTEBRATE SURVIVAL JOURNAL 15, 116-117, 2018 | | 2018 |