Frederick Hughson
Frederick Hughson
Professor of Molecular Biology, Princeton University
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Cited by
Cited by
Structure of influenza haemagglutinin at the pH of membrane fusion
PA Bullough, FM Hughson, JJ Skehel, DC Wiley
Nature 371 (6492), 37-43, 1994
Structural identification of a bacterial quorum-sensing signal containing boron
X Chen, S Schauder, N Potier, A Van Dorsselaer, I Pelczer, BL Bassler, ...
Nature 415 (6871), 545-549, 2002
Structural characterization of a partly folded apomyoglobin intermediate
FM Hughson, PE Wright, RL Baldwin
Science 249 (4976), 1544-1548, 1990
Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2
ST Miller, KB Xavier, SR Campagna, ME Taga, MF Semmelhack, ...
Molecular cell 15 (5), 677-687, 2004
SNARE protein structure and function
D Ungar, FM Hughson
Annual review of cell and developmental biology 19 (1), 493-517, 2003
Sec1p binds to SNARE complexes and concentrates at sites of secretion
CM Carr, E Grote, M Munson, FM Hughson, PJ Novick
The Journal of cell biology 146 (2), 333-344, 1999
Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing
MB Neiditch, MJ Federle, AJ Pompeani, RC Kelly, DL Swem, PD Jeffrey, ...
Cell 126 (6), 1095-1108, 2006
Tethering factors as organizers of intracellular vesicular traffic
IM Yu, FM Hughson
Annual review of cell and developmental biology 26, 137-156, 2010
Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p
KL Nicholson, M Munson, RB Miller, TJ Filip, R Fairman, FM Hughson
Nature structural biology 5 (9), 793-802, 1998
Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2
MB Neiditch, MJ Federle, ST Miller, BL Bassler, FM Hughson
Molecular cell 18 (5), 507-518, 2005
Probing the stability of a partly folded apomyoglobin intermediate by site-directed mutagenesis
FM Hughson, D Barrick, RL Baldwin
Biochemistry 30 (17), 4113-4118, 1991
A strategy for antagonizing quorum sensing
G Chen, LR Swem, DL Swem, DL Stauff, CT O'Loughlin, PD Jeffrey, ...
Molecular cell 42 (2), 199-209, 2011
The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy
WL Yen, T Shintani, U Nair, Y Cao, BC Richardson, Z Li, FM Hughson, ...
Journal of Cell Biology 188 (1), 101-114, 2010
A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation
J Chen, SA Wharton, W WEIssENHORN, LJ Calder, FM Hughson, ...
Proceedings of the National Academy of Sciences 92 (26), 12205-12209, 1995
A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly
RW Baker, PD Jeffrey, M Zick, BP Phillips, WT Wickner, FM Hughson
Science 349 (6252), 1111-1114, 2015
Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly
M Munson, X Chen, AE Cocina, SM Schultz, FM Hughson
Nature structural biology 7 (10), 894-902, 2000
Enveloped viruses: a common mode of membrane fusion?
FM Hughson
Current Biology 7 (9), R565-R569, 1997
Molecular mechanisms of acid denaturation: The role of histidine residues in the partial unfolding of apomyoglobin
D Barrick, FM Hughson, RL Baldwin
Journal of molecular biology 237 (5), 588-601, 1994
A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1
Y Ren, CK Yip, A Tripathi, D Huie, PD Jeffrey, T Walz, FM Hughson
Cell 139 (6), 1119-1129, 2009
Use of site-directed mutagenesis to destabilize native apomyoglobin relative to folding intermediates
FM Hughson, RL Baldwin
Biochemistry 28 (10), 4415-4422, 1989
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